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TLR1/2-driven macrophage polarization shapes memory CD4+T-cell responses across the leprosy spectrum.

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Title: TLR1/2-driven macrophage polarization shapes memory CD4+T-cell responses across the leprosy spectrum.
Authors: Chebli-de-Abreu N; Postgraduate Program in Health Sciences: Infectious Diseases and Tropical Medicine, School of Medicine, Federal University of Minas Gerais (UFMG), Belo Horizonte, Minas Gerais, Brazil; Division of Dermatology, Federal University of Juiz de Fora (UFJF), Juiz de Fora, Minas Gerais, Brazil., Carvalho AMRS; Department of Clinical Pathology, COLTEC, Federal University of Minas Gerais (UFMG), Belo Horizonte, Minas Gerais, Brazil., Menezes YR; Postgraduate Program in Health Sciences: Infectious Diseases and Tropical Medicine, School of Medicine, Federal University of Minas Gerais (UFMG), Belo Horizonte, Minas Gerais, Brazil; Division of Dermatology, Eduardo de Menezes Hospital, Belo Horizonte, Minas Gerais, Brazil., Macedo JM; Postgraduate Program in Health Sciences: Infectious Diseases and Tropical Medicine, School of Medicine, Federal University of Minas Gerais (UFMG), Belo Horizonte, Minas Gerais, Brazil; Division of Dermatology, Eduardo de Menezes Hospital, Belo Horizonte, Minas Gerais, Brazil., França SDT; Division of Dermatology, Eduardo de Menezes Hospital, Belo Horizonte, Minas Gerais, Brazil., Assis BPN; Postgraduate Program in Health Sciences: Infectious Diseases and Tropical Medicine, School of Medicine, Federal University of Minas Gerais (UFMG), Belo Horizonte, Minas Gerais, Brazil; Division of Dermatology, Eduardo de Menezes Hospital, Belo Horizonte, Minas Gerais, Brazil., Minozzo JC; Production and Research Centre of Immunobiological Products, Department of Health of the State of Paraná, Piraquara, Paraná, Brazil., Thomaz-Soccol V; Postgraduate Program in Bioprocess Engineering and Biotechnology, Federal University of Paraná (UFPR), Curitiba, Paraná, Brazil., Lages ATC; Postgraduate Program in Health Sciences: Infectious Diseases and Tropical Medicine, School of Medicine, Federal University of Minas Gerais (UFMG), Belo Horizonte, Minas Gerais, Brazil., Menezes-Souza D; Postgraduate Program in Health Sciences: Infectious Diseases and Tropical Medicine, School of Medicine, Federal University of Minas Gerais (UFMG), Belo Horizonte, Minas Gerais, Brazil; Department of Clinical Pathology, COLTEC, Federal University of Minas Gerais (UFMG), Belo Horizonte, Minas Gerais, Brazil; Postgraduate Program in Parasitology, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil; Vaccine Technology Center (CTVacinas), Belo Horizonte Technology Park (BH-TEC), Belo Horizonte, Minas Gerais, Brazil., Rocha MODC; Postgraduate Program in Health Sciences: Infectious Diseases and Tropical Medicine, School of Medicine, Federal University of Minas Gerais (UFMG), Belo Horizonte, Minas Gerais, Brazil. Electronic address: rochamoc@terra.com.br.
Source: Acta tropica [Acta Trop] 2025 Nov; Vol. 271, pp. 107870. Date of Electronic Publication: 2025 Oct 12.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0370374 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-6254 (Electronic) Linking ISSN: 0001706X NLM ISO Abbreviation: Acta Trop Subsets: MEDLINE
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  Data: TLR1/2-driven macrophage polarization shapes memory CD4<superscript>+</superscript>T-cell responses across the leprosy spectrum.
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  Data: <searchLink fieldCode="AU" term="%22Chebli-de-Abreu+N%22">Chebli-de-Abreu N</searchLink>; Postgraduate Program in Health Sciences: Infectious Diseases and Tropical Medicine, School of Medicine, Federal University of Minas Gerais (UFMG), Belo Horizonte, Minas Gerais, Brazil; Division of Dermatology, Federal University of Juiz de Fora (UFJF), Juiz de Fora, Minas Gerais, Brazil.<br /><searchLink fieldCode="AU" term="%22Carvalho+AMRS%22">Carvalho AMRS</searchLink>; Department of Clinical Pathology, COLTEC, Federal University of Minas Gerais (UFMG), Belo Horizonte, Minas Gerais, Brazil.<br /><searchLink fieldCode="AU" term="%22Menezes+YR%22">Menezes YR</searchLink>; Postgraduate Program in Health Sciences: Infectious Diseases and Tropical Medicine, School of Medicine, Federal University of Minas Gerais (UFMG), Belo Horizonte, Minas Gerais, Brazil; Division of Dermatology, Eduardo de Menezes Hospital, Belo Horizonte, Minas Gerais, Brazil.<br /><searchLink fieldCode="AU" term="%22Macedo+JM%22">Macedo JM</searchLink>; Postgraduate Program in Health Sciences: Infectious Diseases and Tropical Medicine, School of Medicine, Federal University of Minas Gerais (UFMG), Belo Horizonte, Minas Gerais, Brazil; Division of Dermatology, Eduardo de Menezes Hospital, Belo Horizonte, Minas Gerais, Brazil.<br /><searchLink fieldCode="AU" term="%22França+SDT%22">França SDT</searchLink>; Division of Dermatology, Eduardo de Menezes Hospital, Belo Horizonte, Minas Gerais, Brazil.<br /><searchLink fieldCode="AU" term="%22Assis+BPN%22">Assis BPN</searchLink>; Postgraduate Program in Health Sciences: Infectious Diseases and Tropical Medicine, School of Medicine, Federal University of Minas Gerais (UFMG), Belo Horizonte, Minas Gerais, Brazil; Division of Dermatology, Eduardo de Menezes Hospital, Belo Horizonte, Minas Gerais, Brazil.<br /><searchLink fieldCode="AU" term="%22Minozzo+JC%22">Minozzo JC</searchLink>; Production and Research Centre of Immunobiological Products, Department of Health of the State of Paraná, Piraquara, Paraná, Brazil.<br /><searchLink fieldCode="AU" term="%22Thomaz-Soccol+V%22">Thomaz-Soccol V</searchLink>; Postgraduate Program in Bioprocess Engineering and Biotechnology, Federal University of Paraná (UFPR), Curitiba, Paraná, Brazil.<br /><searchLink fieldCode="AU" term="%22Lages+ATC%22">Lages ATC</searchLink>; Postgraduate Program in Health Sciences: Infectious Diseases and Tropical Medicine, School of Medicine, Federal University of Minas Gerais (UFMG), Belo Horizonte, Minas Gerais, Brazil.<br /><searchLink fieldCode="AU" term="%22Menezes-Souza+D%22">Menezes-Souza D</searchLink>; Postgraduate Program in Health Sciences: Infectious Diseases and Tropical Medicine, School of Medicine, Federal University of Minas Gerais (UFMG), Belo Horizonte, Minas Gerais, Brazil; Department of Clinical Pathology, COLTEC, Federal University of Minas Gerais (UFMG), Belo Horizonte, Minas Gerais, Brazil; Postgraduate Program in Parasitology, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil; Vaccine Technology Center (CTVacinas), Belo Horizonte Technology Park (BH-TEC), Belo Horizonte, Minas Gerais, Brazil.<br /><searchLink fieldCode="AU" term="%22Rocha+MODC%22">Rocha MODC</searchLink>; Postgraduate Program in Health Sciences: Infectious Diseases and Tropical Medicine, School of Medicine, Federal University of Minas Gerais (UFMG), Belo Horizonte, Minas Gerais, Brazil. Electronic address: rochamoc@terra.com.br.
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  Data: <searchLink fieldCode="JN" term="%220370374%22">Acta tropica</searchLink> [Acta Trop] 2025 Nov; Vol. 271, pp. 107870. <i>Date of Electronic Publication: </i>2025 Oct 12.
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