Polybromo‑1 Bromodomain Inhibitor Selectivity Is Mediated by a Unique Ligand-Binding Pocket.
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| Title: | Polybromo‑1 Bromodomain Inhibitor Selectivity Is Mediated by a Unique Ligand-Binding Pocket. |
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| Authors: | Nuñez R; Department of Biochemistry, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, United States., Bursch KL; Department of Biochemistry, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, United States., Makowski SJ; Department of Biochemistry, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, United States., Xue M; Synthetic Biology Program, J Craig Venter Institute, La Jolla, California 92037, United States., Cozzolino KA; Synthetic Biology Program, J Craig Venter Institute, La Jolla, California 92037, United States., Shishodia S; Department of Biochemistry, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, United States.; Program in Chemical Biology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, United States., Keyes RF; Department of Biochemistry, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, United States.; Program in Chemical Biology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, United States., Zhu N; Synthetic Biology Program, J Craig Venter Institute, La Jolla, California 92037, United States., Smith BC; Department of Biochemistry, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, United States.; Program in Chemical Biology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, United States. |
| Source: | ACS medicinal chemistry letters [ACS Med Chem Lett] 2025 Sep 16; Vol. 16 (10), pp. 1955-1962. Date of Electronic Publication: 2025 Sep 16 (Print Publication: 2025). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Chemical Society Country of Publication: United States NLM ID: 101521073 Publication Model: eCollection Cited Medium: Print ISSN: 1948-5875 (Print) Linking ISSN: 19485875 NLM ISO Abbreviation: ACS Med Chem Lett Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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