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Localization of the therapeutic targets for endothelin receptor antagonists and sodium-glucose co-transporter 2 inhibitors in the chronic liver disease, primary sclerosing cholangitis.

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Title: Localization of the therapeutic targets for endothelin receptor antagonists and sodium-glucose co-transporter 2 inhibitors in the chronic liver disease, primary sclerosing cholangitis.
Authors: Kuc RE; Experimental Medicine and Immunotherapeutics, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom., Paterson AL; Department of Pathology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom., Williams TL; Experimental Medicine and Immunotherapeutics, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom., Gelson WTH; Department of Medicine, University of Cambridge, Cambridge, United Kingdom.; Cambridge Liver Unit, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom., Greasley PJ; Early Clinical Development, Research and Early Development, Cardiovascular, Renal and Metabolism (CVRM), BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Ambery P; Late-Stage Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Maguire JJ; Experimental Medicine and Immunotherapeutics, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom., Davenport AP; Experimental Medicine and Immunotherapeutics, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom.
Source: Frontiers in pharmacology [Front Pharmacol] 2025 Sep 29; Vol. 16, pp. 1680875. Date of Electronic Publication: 2025 Sep 29 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Media] Country of Publication: Switzerland NLM ID: 101548923 Publication Model: eCollection Cited Medium: Print ISSN: 1663-9812 (Print) Linking ISSN: 16639812 NLM ISO Abbreviation: Front Pharmacol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Localization of the therapeutic targets for endothelin receptor antagonists and sodium-glucose co-transporter 2 inhibitors in the chronic liver disease, primary sclerosing cholangitis.
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  Data: <searchLink fieldCode="AU" term="%22Kuc+RE%22">Kuc RE</searchLink>; Experimental Medicine and Immunotherapeutics, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Paterson+AL%22">Paterson AL</searchLink>; Department of Pathology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Williams+TL%22">Williams TL</searchLink>; Experimental Medicine and Immunotherapeutics, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Gelson+WTH%22">Gelson WTH</searchLink>; Department of Medicine, University of Cambridge, Cambridge, United Kingdom.; Cambridge Liver Unit, Cambridge University Hospitals NHS Foundation Trust, Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Greasley+PJ%22">Greasley PJ</searchLink>; Early Clinical Development, Research and Early Development, Cardiovascular, Renal and Metabolism (CVRM), BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22Ambery+P%22">Ambery P</searchLink>; Late-Stage Development, Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.<br /><searchLink fieldCode="AU" term="%22Maguire+JJ%22">Maguire JJ</searchLink>; Experimental Medicine and Immunotherapeutics, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Davenport+AP%22">Davenport AP</searchLink>; Experimental Medicine and Immunotherapeutics, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom.
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