Comparing the Influence of Heterogeneity on Model Outcomes in Individual-Level and Cohort Simulations: An Exploratory Simulation Study.

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Title: Comparing the Influence of Heterogeneity on Model Outcomes in Individual-Level and Cohort Simulations: An Exploratory Simulation Study.
Authors: van Well EB; Department of Medical Imaging, Radboud University Medical Center, Route 767, PO Box 9101, 6500 HB, Nijmegen, The Netherlands. evelien.vanwell@radboudumc.nl., Govers TM; Medip Analytics, Nijmegen, The Netherlands., Koffijberg H; Health Technology and Services Research Department, Technical Medical Centre, University of Twente, Enschede, The Netherlands.
Source: PharmacoEconomics [Pharmacoeconomics] 2026 Apr; Vol. 44 (4), pp. 429-437. Date of Electronic Publication: 2025 Oct 15.
Publication Type: Journal Article; Comparative Study
Journal Info: Publisher: Adis, Springer International Country of Publication: New Zealand NLM ID: 9212404 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1179-2027 (Electronic) Linking ISSN: 11707690 NLM ISO Abbreviation: Pharmacoeconomics Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Comparing the Influence of Heterogeneity on Model Outcomes in Individual-Level and Cohort Simulations: An Exploratory Simulation Study.
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  Data: <searchLink fieldCode="AU" term="%22van+Well+EB%22">van Well EB</searchLink>; Department of Medical Imaging, Radboud University Medical Center, Route 767, PO Box 9101, 6500 HB, Nijmegen, The Netherlands. evelien.vanwell@radboudumc.nl.<br /><searchLink fieldCode="AU" term="%22Govers+TM%22">Govers TM</searchLink>; Medip Analytics, Nijmegen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Koffijberg+H%22">Koffijberg H</searchLink>; Health Technology and Services Research Department, Technical Medical Centre, University of Twente, Enschede, The Netherlands.
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  Data: <searchLink fieldCode="JN" term="%229212404%22">PharmacoEconomics</searchLink> [Pharmacoeconomics] 2026 Apr; Vol. 44 (4), pp. 429-437. <i>Date of Electronic Publication: </i>2025 Oct 15.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Adis%2C+Springer+International%22">Adis, Springer International </searchLink><i>Country of Publication: </i>New Zealand <i>NLM ID: </i>9212404 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1179-2027 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2211707690%22">11707690 </searchLink><i>NLM ISO Abbreviation: </i>Pharmacoeconomics <i>Subsets: </i>MEDLINE
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        Value: 10.1007/s40273-025-01547-3
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        Text: English
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        StartPage: 429
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      – TitleFull: Comparing the Influence of Heterogeneity on Model Outcomes in Individual-Level and Cohort Simulations: An Exploratory Simulation Study.
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            – D: 01
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              Text: 2026 Apr
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              Y: 2026
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