Diagnostic sequencing identifies high-risk markers and mechanisms of resistance to guide immunotherapy selection.

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Title: Diagnostic sequencing identifies high-risk markers and mechanisms of resistance to guide immunotherapy selection.
Authors: Sudha P; Division of Hematolgy and Oncology, Melvin and Bren Simon Comprehensive Cancer Center, Indiana University School of Medicine, Indianapolis, IN., Pham P; Division of Hematolgy and Oncology, Melvin and Bren Simon Comprehensive Cancer Center, Indiana University School of Medicine, Indianapolis, IN., Niu W; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN., Liu E; Division of Hematolgy and Oncology, Melvin and Bren Simon Comprehensive Cancer Center, Indiana University School of Medicine, Indianapolis, IN., Wang L; Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN., Truong G; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN., Ligocki C; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN., Al-Azzawi R; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN., Surapenini M; Division of Hematolgy and Oncology, Melvin and Bren Simon Comprehensive Cancer Center, Indiana University School of Medicine, Indianapolis, IN., Bray SM; Fountain Life Co, Indianapolis, IN., Vetrini F; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN.; Undiagnosed Rare Disease Clinic, Indiana University School of Medicine, Indianapolis, IN., Czader M; Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN., Tayeh MK; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN., Lee K; Division of Hematolgy and Oncology, Melvin and Bren Simon Comprehensive Cancer Center, Indiana University School of Medicine, Indianapolis, IN., Abonour R; Division of Hematolgy and Oncology, Melvin and Bren Simon Comprehensive Cancer Center, Indiana University School of Medicine, Indianapolis, IN., Suvannasankha A; Division of Hematolgy and Oncology, Melvin and Bren Simon Comprehensive Cancer Center, Indiana University School of Medicine, Indianapolis, IN., Walker BA; Division of Hematolgy and Oncology, Melvin and Bren Simon Comprehensive Cancer Center, Indiana University School of Medicine, Indianapolis, IN.; Center for Computational Biology and Bioinformatics, Indiana University School of Medicine, Indianapolis, IN.; Myeloma Division, Sylvester Comprehensive Cancer Center, Miller School of Medicine, University of Miami, Miami, FL.
Source: Blood advances [Blood Adv] 2026 Jan 13; Vol. 10 (1), pp. 95-105.
Publication Type: Journal Article
Journal Info: Publisher: American Society of Hematology Country of Publication: United States NLM ID: 101698425 Publication Model: Print Cited Medium: Internet ISSN: 2473-9537 (Electronic) Linking ISSN: 24739529 NLM ISO Abbreviation: Blood Adv Subsets: MEDLINE
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  Data: Diagnostic sequencing identifies high-risk markers and mechanisms of resistance to guide immunotherapy selection.
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  Data: <searchLink fieldCode="AU" term="%22Sudha+P%22">Sudha P</searchLink>; Division of Hematolgy and Oncology, Melvin and Bren Simon Comprehensive Cancer Center, Indiana University School of Medicine, Indianapolis, IN.<br /><searchLink fieldCode="AU" term="%22Pham+P%22">Pham P</searchLink>; Division of Hematolgy and Oncology, Melvin and Bren Simon Comprehensive Cancer Center, Indiana University School of Medicine, Indianapolis, IN.<br /><searchLink fieldCode="AU" term="%22Niu+W%22">Niu W</searchLink>; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN.<br /><searchLink fieldCode="AU" term="%22Liu+E%22">Liu E</searchLink>; Division of Hematolgy and Oncology, Melvin and Bren Simon Comprehensive Cancer Center, Indiana University School of Medicine, Indianapolis, IN.<br /><searchLink fieldCode="AU" term="%22Wang+L%22">Wang L</searchLink>; Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN.<br /><searchLink fieldCode="AU" term="%22Truong+G%22">Truong G</searchLink>; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN.<br /><searchLink fieldCode="AU" term="%22Ligocki+C%22">Ligocki C</searchLink>; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN.<br /><searchLink fieldCode="AU" term="%22Al-Azzawi+R%22">Al-Azzawi R</searchLink>; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN.<br /><searchLink fieldCode="AU" term="%22Surapenini+M%22">Surapenini M</searchLink>; Division of Hematolgy and Oncology, Melvin and Bren Simon Comprehensive Cancer Center, Indiana University School of Medicine, Indianapolis, IN.<br /><searchLink fieldCode="AU" term="%22Bray+SM%22">Bray SM</searchLink>; Fountain Life Co, Indianapolis, IN.<br /><searchLink fieldCode="AU" term="%22Vetrini+F%22">Vetrini F</searchLink>; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN.; Undiagnosed Rare Disease Clinic, Indiana University School of Medicine, Indianapolis, IN.<br /><searchLink fieldCode="AU" term="%22Czader+M%22">Czader M</searchLink>; Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, IN.<br /><searchLink fieldCode="AU" term="%22Tayeh+MK%22">Tayeh MK</searchLink>; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN.<br /><searchLink fieldCode="AU" term="%22Lee+K%22">Lee K</searchLink>; Division of Hematolgy and Oncology, Melvin and Bren Simon Comprehensive Cancer Center, Indiana University School of Medicine, Indianapolis, IN.<br /><searchLink fieldCode="AU" term="%22Abonour+R%22">Abonour R</searchLink>; Division of Hematolgy and Oncology, Melvin and Bren Simon Comprehensive Cancer Center, Indiana University School of Medicine, Indianapolis, IN.<br /><searchLink fieldCode="AU" term="%22Suvannasankha+A%22">Suvannasankha A</searchLink>; Division of Hematolgy and Oncology, Melvin and Bren Simon Comprehensive Cancer Center, Indiana University School of Medicine, Indianapolis, IN.<br /><searchLink fieldCode="AU" term="%22Walker+BA%22">Walker BA</searchLink>; Division of Hematolgy and Oncology, Melvin and Bren Simon Comprehensive Cancer Center, Indiana University School of Medicine, Indianapolis, IN.; Center for Computational Biology and Bioinformatics, Indiana University School of Medicine, Indianapolis, IN.; Myeloma Division, Sylvester Comprehensive Cancer Center, Miller School of Medicine, University of Miami, Miami, FL.
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              Text: 2026 Jan 13
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