A melanocortin 4- and glucagon-like peptide 1 receptor multiple agonist for the treatment of diabetes and obesity.

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Title: A melanocortin 4- and glucagon-like peptide 1 receptor multiple agonist for the treatment of diabetes and obesity.
Authors: Ashlaw EF; Syracuse University, Department of Chemistry, 111 College Place, Syracuse, NY, 13244, USA., Elfers CT; Seattle Children's Research Institute, Seattle, WA, 98195, USA; University of Washington School of Medicine, Department of Pediatrics, Seattle, WA, 98195, USA., Chichura KS; Syracuse University, Department of Chemistry, 111 College Place, Syracuse, NY, 13244, USA., Miranda IC; Syracuse University, Department of Chemistry, 111 College Place, Syracuse, NY, 13244, USA., McGivney A; Syracuse University, Department of Chemistry, 111 College Place, Syracuse, NY, 13244, USA., Chepurny OG; State University of New York, Upstate Medical University, Department of Medicine, Syracuse, NY, 13245, USA., Holz GG; State University of New York, Upstate Medical University, Department of Medicine, Syracuse, NY, 13245, USA; State University of New York, Upstate Medical University, Department of Pharmacology, Syracuse, NY, 13245, USA., Mullins G; Seattle Children's Research Institute, Seattle, WA, 98195, USA., den Hartigh LJ; University of Washington, Department of Medicine, Division of Metabolism, Endocrinology and Nutrition, UW Medicine Diabetes Institute, Seattle, WA, 98195, USA., Liu Y; University of Washington, Department of Laboratory Medicine and Pathology, Seattle, WA, 98195, USA., Roth CL; Seattle Children's Research Institute, Seattle, WA, 98195, USA; University of Washington School of Medicine, Department of Pediatrics, Seattle, WA, 98195, USA. Electronic address: Christian.roth@seattlechildrens.org., Doyle RP; Syracuse University, Department of Chemistry, 111 College Place, Syracuse, NY, 13244, USA; State University of New York, Upstate Medical University, Department of Medicine, Syracuse, NY, 13245, USA; State University of New York, Upstate Medical University, Department of Pharmacology, Syracuse, NY, 13245, USA. Electronic address: rpdoyle@syr.edu.
Source: Metabolism: clinical and experimental [Metabolism] 2026 Jan; Vol. 174, pp. 156414. Date of Electronic Publication: 2025 Oct 13.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Inc Country of Publication: United States NLM ID: 0375267 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-8600 (Electronic) Linking ISSN: 00260495 NLM ISO Abbreviation: Metabolism Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1532-8600
DOI:10.1016/j.metabol.2025.156414