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The formation of the 'footprint of death' as a mechanism for generating large substrate-bound extracellular vesicles that mark the site of cell death.

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Title: The formation of the 'footprint of death' as a mechanism for generating large substrate-bound extracellular vesicles that mark the site of cell death.
Authors: Rutter SF; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC, Australia.; Research Centre for Extracellular Vesicles, La Trobe University, Melbourne, VIC, Australia., Kang T; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC, Australia.; Research Centre for Extracellular Vesicles, La Trobe University, Melbourne, VIC, Australia., Ryan GF; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC, Australia.; Research Centre for Extracellular Vesicles, La Trobe University, Melbourne, VIC, Australia., Shi B; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC, Australia.; Research Centre for Extracellular Vesicles, La Trobe University, Melbourne, VIC, Australia., Vella CL; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC, Australia.; Research Centre for Extracellular Vesicles, La Trobe University, Melbourne, VIC, Australia.; Centre for Cardiovascular Biology and Disease Research, La Trobe Institute for Molecular Science, La Trobe University, Bundoora, VIC, Australia., Rajasekhar P; The Walter and Eliza Hall Institute of Medial Research, Parkville, VIC, Australia.; University of Melbourne, Melbourne, VIC, Australia., Cutter SW; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC, Australia., Hodge AL; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC, Australia., Ozkocak DC; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC, Australia.; Research Centre for Extracellular Vesicles, La Trobe University, Melbourne, VIC, Australia., Ang CS; The Bio21 Institute of Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, VIC, Australia., Ratcliffe J; Bioimaging Platform, La Trobe University, Melbourne, VIC, Australia., Binger KJ; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC, Australia., Foneska P; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC, Australia.; Research Centre for Extracellular Vesicles, La Trobe University, Melbourne, VIC, Australia., Mathivanan S; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC, Australia.; Research Centre for Extracellular Vesicles, La Trobe University, Melbourne, VIC, Australia., Geoghegan ND; The Walter and Eliza Hall Institute of Medial Research, Parkville, VIC, Australia.; University of Melbourne, Melbourne, VIC, Australia., Rogers KL; The Walter and Eliza Hall Institute of Medial Research, Parkville, VIC, Australia.; University of Melbourne, Melbourne, VIC, Australia., Olson MF; Department of Chemistry and Biology, Toronto Metropolitan University, Toronto, ON, Canada., Atkin-Smith GK; The Walter and Eliza Hall Institute of Medial Research, Parkville, VIC, Australia. atkinsmith.g@wehi.edu.au.; University of Melbourne, Melbourne, VIC, Australia. atkinsmith.g@wehi.edu.au., Poon IKH; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC, Australia. i.poon@latrobe.edu.au.; Research Centre for Extracellular Vesicles, La Trobe University, Melbourne, VIC, Australia. i.poon@latrobe.edu.au.
Source: Nature communications [Nat Commun] 2025 Oct 15; Vol. 16 (1), pp. 9160. Date of Electronic Publication: 2025 Oct 15.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Rutter+SF%22">Rutter SF</searchLink>; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC, Australia.; Research Centre for Extracellular Vesicles, La Trobe University, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Kang+T%22">Kang T</searchLink>; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC, Australia.; Research Centre for Extracellular Vesicles, La Trobe University, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Ryan+GF%22">Ryan GF</searchLink>; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC, Australia.; Research Centre for Extracellular Vesicles, La Trobe University, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Shi+B%22">Shi B</searchLink>; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC, Australia.; Research Centre for Extracellular Vesicles, La Trobe University, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Vella+CL%22">Vella CL</searchLink>; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC, Australia.; Research Centre for Extracellular Vesicles, La Trobe University, Melbourne, VIC, Australia.; Centre for Cardiovascular Biology and Disease Research, La Trobe Institute for Molecular Science, La Trobe University, Bundoora, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Rajasekhar+P%22">Rajasekhar P</searchLink>; The Walter and Eliza Hall Institute of Medial Research, Parkville, VIC, Australia.; University of Melbourne, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Cutter+SW%22">Cutter SW</searchLink>; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Hodge+AL%22">Hodge AL</searchLink>; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Ozkocak+DC%22">Ozkocak DC</searchLink>; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC, Australia.; Research Centre for Extracellular Vesicles, La Trobe University, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Ang+CS%22">Ang CS</searchLink>; The Bio21 Institute of Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Ratcliffe+J%22">Ratcliffe J</searchLink>; Bioimaging Platform, La Trobe University, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Binger+KJ%22">Binger KJ</searchLink>; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Foneska+P%22">Foneska P</searchLink>; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC, Australia.; Research Centre for Extracellular Vesicles, La Trobe University, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Mathivanan+S%22">Mathivanan S</searchLink>; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC, Australia.; Research Centre for Extracellular Vesicles, La Trobe University, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Geoghegan+ND%22">Geoghegan ND</searchLink>; The Walter and Eliza Hall Institute of Medial Research, Parkville, VIC, Australia.; University of Melbourne, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Rogers+KL%22">Rogers KL</searchLink>; The Walter and Eliza Hall Institute of Medial Research, Parkville, VIC, Australia.; University of Melbourne, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Olson+MF%22">Olson MF</searchLink>; Department of Chemistry and Biology, Toronto Metropolitan University, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Atkin-Smith+GK%22">Atkin-Smith GK</searchLink>; The Walter and Eliza Hall Institute of Medial Research, Parkville, VIC, Australia. atkinsmith.g@wehi.edu.au.; University of Melbourne, Melbourne, VIC, Australia. atkinsmith.g@wehi.edu.au.<br /><searchLink fieldCode="AU" term="%22Poon+IKH%22">Poon IKH</searchLink>; Department of Biochemistry and Chemistry, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, VIC, Australia. i.poon@latrobe.edu.au.; Research Centre for Extracellular Vesicles, La Trobe University, Melbourne, VIC, Australia. i.poon@latrobe.edu.au.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2025 Oct 15; Vol. 16 (1), pp. 9160. <i>Date of Electronic Publication: </i>2025 Oct 15.
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