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A vaccine central in A(H5) influenza antigenic space confers broad immunity.

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Title: A vaccine central in A(H5) influenza antigenic space confers broad immunity.
Authors: Kok A; Department of Viroscience, Erasmus University Medical Center, Rotterdam, The Netherlands.; Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research, Department of Chemistry, Faculty of Science, Utrecht University, Utrecht, The Netherlands., Wilks SH; Center for Pathogen Evolution, University of Cambridge, Cambridge, UK.; Institute for Electrical and Electronic Engineering, Faculty of Engineering and Information Technology, University of Melbourne, Melbourne, Victoria, Australia., Tureli S; Center for Pathogen Evolution, University of Cambridge, Cambridge, UK., James SL; Center for Pathogen Evolution, University of Cambridge, Cambridge, UK., Bestebroer TM; Department of Viroscience, Erasmus University Medical Center, Rotterdam, The Netherlands., Burke DF; Center for Pathogen Evolution, University of Cambridge, Cambridge, UK.; Centre for Host-Microbiome Interactions, King's College, London Tower Wing, Guy's Hospital, London, UK., Funk M; Department of Viroscience, Erasmus University Medical Center, Rotterdam, The Netherlands., van der Vliet S; Department of Viroscience, Erasmus University Medical Center, Rotterdam, The Netherlands., Spronken MI; Department of Viroscience, Erasmus University Medical Center, Rotterdam, The Netherlands., Rijnink WF; Department of Viroscience, Erasmus University Medical Center, Rotterdam, The Netherlands., Pattinson DJ; Center for Pathogen Evolution, University of Cambridge, Cambridge, UK.; Influenza Research Institute, Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI, USA., de Meulder D; Department of Viroscience, Erasmus University Medical Center, Rotterdam, The Netherlands., Rosu ME; Department of Viroscience, Erasmus University Medical Center, Rotterdam, The Netherlands., Lexmond P; Department of Viroscience, Erasmus University Medical Center, Rotterdam, The Netherlands., van den Brand JMA; Division of Pathology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands., Herfst S; Department of Viroscience, Erasmus University Medical Center, Rotterdam, The Netherlands., Smith DJ; Center for Pathogen Evolution, University of Cambridge, Cambridge, UK., Fouchier RAM; Department of Viroscience, Erasmus University Medical Center, Rotterdam, The Netherlands., Richard M; Department of Viroscience, Erasmus University Medical Center, Rotterdam, The Netherlands. m.richard@erasmusmc.nl.
Source: Nature [Nature] 2025 Nov; Vol. 647 (8091), pp. 1005-1013. Date of Electronic Publication: 2025 Oct 15.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE
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  Data: A vaccine central in A(H5) influenza antigenic space confers broad immunity.
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  Data: <searchLink fieldCode="AU" term="%22Kok+A%22">Kok A</searchLink>; Department of Viroscience, Erasmus University Medical Center, Rotterdam, The Netherlands.; Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research, Department of Chemistry, Faculty of Science, Utrecht University, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Wilks+SH%22">Wilks SH</searchLink>; Center for Pathogen Evolution, University of Cambridge, Cambridge, UK.; Institute for Electrical and Electronic Engineering, Faculty of Engineering and Information Technology, University of Melbourne, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Tureli+S%22">Tureli S</searchLink>; Center for Pathogen Evolution, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22James+SL%22">James SL</searchLink>; Center for Pathogen Evolution, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Bestebroer+TM%22">Bestebroer TM</searchLink>; Department of Viroscience, Erasmus University Medical Center, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Burke+DF%22">Burke DF</searchLink>; Center for Pathogen Evolution, University of Cambridge, Cambridge, UK.; Centre for Host-Microbiome Interactions, King's College, London Tower Wing, Guy's Hospital, London, UK.<br /><searchLink fieldCode="AU" term="%22Funk+M%22">Funk M</searchLink>; Department of Viroscience, Erasmus University Medical Center, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+der+Vliet+S%22">van der Vliet S</searchLink>; Department of Viroscience, Erasmus University Medical Center, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Spronken+MI%22">Spronken MI</searchLink>; Department of Viroscience, Erasmus University Medical Center, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Rijnink+WF%22">Rijnink WF</searchLink>; Department of Viroscience, Erasmus University Medical Center, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Pattinson+DJ%22">Pattinson DJ</searchLink>; Center for Pathogen Evolution, University of Cambridge, Cambridge, UK.; Influenza Research Institute, Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, WI, USA.<br /><searchLink fieldCode="AU" term="%22de+Meulder+D%22">de Meulder D</searchLink>; Department of Viroscience, Erasmus University Medical Center, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Rosu+ME%22">Rosu ME</searchLink>; Department of Viroscience, Erasmus University Medical Center, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Lexmond+P%22">Lexmond P</searchLink>; Department of Viroscience, Erasmus University Medical Center, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+den+Brand+JMA%22">van den Brand JMA</searchLink>; Division of Pathology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Herfst+S%22">Herfst S</searchLink>; Department of Viroscience, Erasmus University Medical Center, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Smith+DJ%22">Smith DJ</searchLink>; Center for Pathogen Evolution, University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Fouchier+RAM%22">Fouchier RAM</searchLink>; Department of Viroscience, Erasmus University Medical Center, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Richard+M%22">Richard M</searchLink>; Department of Viroscience, Erasmus University Medical Center, Rotterdam, The Netherlands. m.richard@erasmusmc.nl.
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  Data: <searchLink fieldCode="JN" term="%220410462%22">Nature</searchLink> [Nature] 2025 Nov; Vol. 647 (8091), pp. 1005-1013. <i>Date of Electronic Publication: </i>2025 Oct 15.
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