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Combining CAR T-Cell Therapy and Nivolumab to Overcome Immune Resistance in THRLBCL: A Case Report.

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Title: Combining CAR T-Cell Therapy and Nivolumab to Overcome Immune Resistance in THRLBCL: A Case Report.
Authors: Munarriz D; Department of Hematology, Hospital Clínic, 08036 Barcelona, Spain., López-Godino O; Department of Hematology, Centro Regional de Hemodonación, IMIB-Pascual Parrilla, Hospital Universitario Morales-Meseguer, 30008 Murcia, Spain., Martinez-Cibrian N; Department of Hematology, Hospital Clínic, 08036 Barcelona, Spain.; Faculty of Medicine, University of Barcelona, 08007 Barcelona, Spain., Albiol N; Department of Hematology, Hospital Clínic, 08036 Barcelona, Spain.; Faculty of Medicine, University of Barcelona, 08007 Barcelona, Spain., Brillembourg H; Department of Hematology, Hospital Clínic, 08036 Barcelona, Spain., Navarro-Velázquez S; Faculty of Medicine, University of Barcelona, 08007 Barcelona, Spain.; Department of Immunology, Hospital Clínic, 08036 Barcelona, Spain.; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain., Español-Rego M; Department of Immunology, Hospital Clínic, 08036 Barcelona, Spain.; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain., Casanueva S; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain., García-Tomás L; Department of Hematology, Centro Regional de Hemodonación, IMIB-Pascual Parrilla, Hospital Universitario Morales-Meseguer, 30008 Murcia, Spain., Muñoz-Sanchez G; Department of Immunology, Hospital Clínic, 08036 Barcelona, Spain.; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain., Alserawan L; Department of Immunology, Hospital Clínic, 08036 Barcelona, Spain.; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain., Benitez-Ribas D; Department of Immunology, Hospital Clínic, 08036 Barcelona, Spain.; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain., Magnano L; Department of Hematology, Hospital Clínic, 08036 Barcelona, Spain.; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain., Correa JG; Department of Hematology, Hospital Clínic, 08036 Barcelona, Spain., Rivero A; Department of Hematology, Hospital Clínic, 08036 Barcelona, Spain.; Faculty of Medicine, University of Barcelona, 08007 Barcelona, Spain., Mozas P; Department of Hematology, Hospital Clínic, 08036 Barcelona, Spain.; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain., Gine E; Department of Hematology, Hospital Clínic, 08036 Barcelona, Spain.; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain., Rodríguez-Lobato LG; Department of Hematology, Hospital Clínic, 08036 Barcelona, Spain.; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain., Martínez-Roca A; Department of Hematology, Hospital Clínic, 08036 Barcelona, Spain.; Faculty of Medicine, University of Barcelona, 08007 Barcelona, Spain., Montoro-Lorite M; Department of Hematology, Hospital Clínic, 08036 Barcelona, Spain., Ayora P; Department of Hematology, Hospital Clínic, 08036 Barcelona, Spain., Esteve J; Department of Hematology, Hospital Clínic, 08036 Barcelona, Spain.; Faculty of Medicine, University of Barcelona, 08007 Barcelona, Spain.; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain., Frutos L; Department of Nuclear Medicine, Hospital C.U. Virgen de la Arrixaca, 30120 Murcia, Spain., Balagué-Ponz O; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain.; Department of Pathology, Hospital Clínic de Barcelona, 08036 Barcelona, Spain., Urbano-Ispizua A; Department of Hematology, Hospital Clínic, 08036 Barcelona, Spain.; Faculty of Medicine, University of Barcelona, 08007 Barcelona, Spain.; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain.; Josep Carreras Research Institute, 08916 Barcelona, Spain., González-Navarro EA; Department of Immunology, Hospital Clínic, 08036 Barcelona, Spain.; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain., Juan M; Faculty of Medicine, University of Barcelona, 08007 Barcelona, Spain.; Department of Immunology, Hospital Clínic, 08036 Barcelona, Spain.; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain.; Clínic-Sant Joan de Déu Immunotherapy Platform, 08036 Barcelona, Spain., Delgado J; Department of Hematology, Hospital Clínic, 08036 Barcelona, Spain.; Faculty of Medicine, University of Barcelona, 08007 Barcelona, Spain.; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain., Ortiz-Maldonado V; Department of Hematology, Hospital Clínic, 08036 Barcelona, Spain.; Faculty of Medicine, University of Barcelona, 08007 Barcelona, Spain.; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain.; Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA.
Source: International journal of molecular sciences [Int J Mol Sci] 2025 Sep 23; Vol. 26 (19). Date of Electronic Publication: 2025 Sep 23.
Publication Type: Case Reports; Journal Article
Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
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Description
ISSN:1422-0067
DOI:10.3390/ijms26199265