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Integrating multi-modal omics to identify therapeutic atherosclerosis pathways for coronary heart disease.

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Title: Integrating multi-modal omics to identify therapeutic atherosclerosis pathways for coronary heart disease.
Authors: de Ruiter SC; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands., van Vugt M; Department of Cardiology, Amsterdam Cardiovascular Sciences, Amsterdam University Medical Centres, University of Amsterdam, Amsterdam, the Netherlands; Faculty of Population Health, Institute of Cardiovascular Science, University College London, London, United Kingdom; Division of Heart and Lungs, Department of Cardiology, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands., Finan C; Faculty of Population Health, Institute of Cardiovascular Science, University College London, London, United Kingdom; Division of Heart and Lungs, Department of Cardiology, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands; UCL British Heart Foundation Research Accelerator, London, United Kingdom; Health Data Research UK and Institute of Health Informatics, University College London, London, United Kingdom., Grobbee DE; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands., de Kleijn DPV; Department of Vascular Surgery, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands., Pasterkamp G; Central Diagnostic Laboratory, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands., den Ruijter HM; Laboratory of Experimental Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands., Benavente ED; Laboratory of Experimental Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands., Peters SAE; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands; The George Institute for Global Health, School of Public Health, Imperial College London, London, UK., Schmidt AF; Department of Cardiology, Amsterdam Cardiovascular Sciences, Amsterdam University Medical Centres, University of Amsterdam, Amsterdam, the Netherlands; Faculty of Population Health, Institute of Cardiovascular Science, University College London, London, United Kingdom; Division of Heart and Lungs, Department of Cardiology, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands; UCL British Heart Foundation Research Accelerator, London, United Kingdom. Electronic address: amand.schmidt@ucl.ac.uk.
Source: EBioMedicine [EBioMedicine] 2025 Nov; Vol. 121, pp. 105966. Date of Electronic Publication: 2025 Oct 15.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101647039 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2352-3964 (Electronic) Linking ISSN: 23523964 NLM ISO Abbreviation: EBioMedicine Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22de+Ruiter+SC%22">de Ruiter SC</searchLink>; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Vugt+M%22">van Vugt M</searchLink>; Department of Cardiology, Amsterdam Cardiovascular Sciences, Amsterdam University Medical Centres, University of Amsterdam, Amsterdam, the Netherlands; Faculty of Population Health, Institute of Cardiovascular Science, University College London, London, United Kingdom; Division of Heart and Lungs, Department of Cardiology, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Finan+C%22">Finan C</searchLink>; Faculty of Population Health, Institute of Cardiovascular Science, University College London, London, United Kingdom; Division of Heart and Lungs, Department of Cardiology, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands; UCL British Heart Foundation Research Accelerator, London, United Kingdom; Health Data Research UK and Institute of Health Informatics, University College London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Grobbee+DE%22">Grobbee DE</searchLink>; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.<br /><searchLink fieldCode="AU" term="%22de+Kleijn+DPV%22">de Kleijn DPV</searchLink>; Department of Vascular Surgery, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Pasterkamp+G%22">Pasterkamp G</searchLink>; Central Diagnostic Laboratory, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.<br /><searchLink fieldCode="AU" term="%22den+Ruijter+HM%22">den Ruijter HM</searchLink>; Laboratory of Experimental Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Benavente+ED%22">Benavente ED</searchLink>; Laboratory of Experimental Cardiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Peters+SAE%22">Peters SAE</searchLink>; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands; The George Institute for Global Health, School of Public Health, Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Schmidt+AF%22">Schmidt AF</searchLink>; Department of Cardiology, Amsterdam Cardiovascular Sciences, Amsterdam University Medical Centres, University of Amsterdam, Amsterdam, the Netherlands; Faculty of Population Health, Institute of Cardiovascular Science, University College London, London, United Kingdom; Division of Heart and Lungs, Department of Cardiology, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands; UCL British Heart Foundation Research Accelerator, London, United Kingdom. Electronic address: amand.schmidt@ucl.ac.uk.
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              Text: 2025 Nov
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