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Genetic determinants and genomic consequences of non-leukemogenic somatic point mutations.

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Title: Genetic determinants and genomic consequences of non-leukemogenic somatic point mutations.
Authors: Weinstock JS; Department of Human Genetics, School of Medicine, Emory University, Atlanta, GA, USA. josh.weinstock@emory.edu., Chaudhry SA; Division of Cardiology, Department of Medicine, Johns Hopkins University, Baltimore, MD, USA.; Department of Surgery, Division of Vascular and Endovascular Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA., Ioannou M; Division of Hematological Malignancies, Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Viskadourou M; Division of Cardiology, Department of Medicine, Johns Hopkins University, Baltimore, MD, USA., Reventun P; Division of Cardiology, Department of Medicine, Johns Hopkins University, Baltimore, MD, USA., Jakubek YA; Department of Internal Medicine, University of Kentucky, Lexington, KY, USA., Liggett LA; Division of Hematology/Oncology, Boston Children's Hospital and Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Laurie C; Department of Biostatistics, University of Washington, Seattle, WA, USA., Broome JG; Division of Medical Genetics, Department of Medicine, University of Washington, Seattle, WA, USA., Khan A; Department of Biostatistics, University of Washington, Seattle, WA, USA., Taylor KD; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Guo X; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Peyser PA; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Boerwinkle E; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA., Chami N; The Charles Bronfman Institute of Personalized Medicine, New York, NY, USA.; The Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Kenny EE; Institute for Genomic Health, York, NY, USA., Loos RJ; The Charles Bronfman Institute of Personalized Medicine, New York, NY, USA.; The Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Psaty BM; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA.; Department of Epidemiology, University of Washington, Seattle, WA, USA.; Department of Health Systems and Population Health, University of Washington, Seattle, WA, USA., Tracy RP; Department of Pathology & Laboratory Medicine and Biochemistry, Larner College of Medicine at the University of Vermont, Colchester, VT, USA., Brody JA; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, WA, USA., Yun JH; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA., Cho MH; Channing Division of Network Medicine and Division of Pulmonary and Critical Care Medicine, Brigham and Women's Hospital, Boston, MA, USA., Vasan RS; National Heart Lung and Blood Institute's, Boston University's Framingham Heart Study, Framingham, MA, USA., Kardia SL; Department of Epidemiology, University of Michigan, Ann Arbor, MI, USA., Smith JA; Department of Epidemiology, University of Michigan, Ann Arbor, MI, USA.; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA., Raffield LM; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA., Bidulescu A; Department of Epidemiology and Biostatistics, Indiana University School of Public Health - Bloomington, Bloomington, IN, USA., O'Brien EC; Duke Clinical Research Institute, Durham, NC, USA., de Andrade M; Mayo Clinic, Department of Health Sciences Research, Rochester, MN, USA., Rotter JI; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Rich SS; Department of Public Health Sciences, Center for Public Health Genomics, University of Virginia, Charlottesville, VA, USA., Tracy RP; Department of Pathology & Laboratory Medicine and Biochemistry, Larner College of Medicine at the University of Vermont, Colchester, VT, USA., Chen YI; The Institute for Translational Genomics and Population Sciences, Department of Pediatrics, The Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center, Torrance, CA, USA., Gu CC; Center for Biostatistics and Data Sciences, Washington University, St. Louis, MO, USA., Hsiung CA; Department of Medicine, Taipei Veterans General Hospital, Taipei Taiwan, Taipei, Taiwan., Kooperberg C; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Haring B; Department of Medicine III, Saarland University Hospital, Homburg, Saarland, Germany; Department of Medicine I, University of Würzburg, Würzburg, Bavaria, Germany.; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, New York, USA., Nassir R; University of California Davis, Davis, CA, USA., Mathias R; Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Reiner A; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Sankaran VG; Division of Hematology/Oncology, Boston Children's Hospital and Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.; Howard Hughes Medical Institute, Boston, MA, USA., Lowenstein CJ; Department of Medicine, Cardiology Division, Johns Hopkins University, Baltimore, MD, USA., Blackwell TW; Center for Statistical Genetics, Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA., Abecasis GR; Center for Statistical Genetics, Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA.; Regeneron Pharmaceuticals, Tarrytown, NY, USA., Smith AV; Center for Statistical Genetics, Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA., Kang HM; Center for Statistical Genetics, Department of Biostatistics, University of Michigan School of Public Health, Ann Arbor, MI, USA., Natarajan P; Center for Genomic Medicine and Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA.; Program in Medical and Population Genetics, Broad Institute of Harvard & MIT, Cambridge, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Jaiswal S; Department of Pathology, Stanford University, Stanford, CA, USA., Bick A; Division of Genetic Medicine, Department of Medicine, Vanderbilt University, Nashville, TN, USA., Post WS; Department of Medicine, Cardiology Division, Johns Hopkins University, Baltimore, MD, USA., Scheet P; Department of Epidemiology, University of Texas M.D. Anderson Cancer Center, Houston, TX, USA., Auer P; Department of Biostatistics, Medical College of Wisconsin, Division of Biostatistics, Institute for Health and Equity, and Cancer Center, Medical College of Wisconsin, Milwaukee, WI, USA., Karantanos T; Division of Hematological Malignancies, Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Battle A; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA. ajbattle@jhu.edu.; Malone Center for Engineering in Healthcare, Johns Hopkins University, Baltimore, MD, USA. ajbattle@jhu.edu.; Department of Computer Science, Johns Hopkins University, Baltimore, MD, USA. ajbattle@jhu.edu., Arvanitis M; Division of Cardiology, Department of Medicine, Johns Hopkins University, Baltimore, MD, USA. marvani1@jhmi.edu.; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA. marvani1@jhmi.edu.
Source: Nature communications [Nat Commun] 2025 Oct 16; Vol. 16 (1), pp. 9194. Date of Electronic Publication: 2025 Oct 16.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Genetic determinants and genomic consequences of non-leukemogenic somatic point mutations.
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          Name:
            NameFull: Jaiswal S
      – PersonEntity:
          Name:
            NameFull: Bick A
      – PersonEntity:
          Name:
            NameFull: Post WS
      – PersonEntity:
          Name:
            NameFull: Scheet P
      – PersonEntity:
          Name:
            NameFull: Auer P
      – PersonEntity:
          Name:
            NameFull: Karantanos T
      – PersonEntity:
          Name:
            NameFull: Battle A
      – PersonEntity:
          Name:
            NameFull: Arvanitis M
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 16
              M: 10
              Text: 2025 Oct 16
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-electronic
              Value: 2041-1723
          Numbering:
            – Type: volume
              Value: 16
            – Type: issue
              Value: 1
          Titles:
            – TitleFull: Nature communications
              Type: main
ResultId 1