Partial removal of visceral epididymal white adipose tissue in obese Ldlr-/-.Leiden mice impacts adipokine secretion, plasma free fatty acids, and improves cerebrovascular health.

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Title: Partial removal of visceral epididymal white adipose tissue in obese Ldlr-/-.Leiden mice impacts adipokine secretion, plasma free fatty acids, and improves cerebrovascular health.
Authors: Seidel F; Department Medical Imaging, Anatomy, Preclinical Imaging Center, Radboud Alzheimer Center, Donders Institute for Brain, Cognition, and Behavior, Radboud university medical center, Nijmegen, The Netherlands.; Department of Metabolic Health Research, Netherlands Organisation for Applied Scientific Research (TNO), Leiden, The Netherlands., Morrison MC; Department of Metabolic Health Research, Netherlands Organisation for Applied Scientific Research (TNO), Leiden, The Netherlands., Arnoldussen I; Department Medical Imaging, Anatomy, Preclinical Imaging Center, Radboud Alzheimer Center, Donders Institute for Brain, Cognition, and Behavior, Radboud university medical center, Nijmegen, The Netherlands., Verweij V; Department Medical Imaging, Anatomy, Preclinical Imaging Center, Radboud Alzheimer Center, Donders Institute for Brain, Cognition, and Behavior, Radboud university medical center, Nijmegen, The Netherlands., Ebert S; Division of Vascular Biology, Institute for Stroke and Dementia Research (ISD), LMU Klinikum, Ludwig Maximilian University (LMU) Munich, Munich, Germany., Attema J; Department of Metabolic Health Research, Netherlands Organisation for Applied Scientific Research (TNO), Leiden, The Netherlands., de Ruiter C; Department of Metabolic Health Research, Netherlands Organisation for Applied Scientific Research (TNO), Leiden, The Netherlands., van Duyvenvoorde W; Department of Metabolic Health Research, Netherlands Organisation for Applied Scientific Research (TNO), Leiden, The Netherlands., Snabel J; Department of Metabolic Health Research, Netherlands Organisation for Applied Scientific Research (TNO), Leiden, The Netherlands., Geenen B; Department Medical Imaging, Anatomy, Preclinical Imaging Center, Radboud Alzheimer Center, Donders Institute for Brain, Cognition, and Behavior, Radboud university medical center, Nijmegen, The Netherlands., Franco A; Department Medical Imaging, Anatomy, Preclinical Imaging Center, Radboud Alzheimer Center, Donders Institute for Brain, Cognition, and Behavior, Radboud university medical center, Nijmegen, The Netherlands., Gart E; Department of Metabolic Health Research, Netherlands Organisation for Applied Scientific Research (TNO), Leiden, The Netherlands., Bernhagen J; Division of Vascular Biology, Institute for Stroke and Dementia Research (ISD), LMU Klinikum, Ludwig Maximilian University (LMU) Munich, Munich, Germany.; German Center for Cardiovascular Research (DZHK), partner site Munich Heart Alliance, Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany., Wiesmann M; Department Medical Imaging, Anatomy, Preclinical Imaging Center, Radboud Alzheimer Center, Donders Institute for Brain, Cognition, and Behavior, Radboud university medical center, Nijmegen, The Netherlands., Kleemann R; Department of Metabolic Health Research, Netherlands Organisation for Applied Scientific Research (TNO), Leiden, The Netherlands., Kiliaan AJ; Department Medical Imaging, Anatomy, Preclinical Imaging Center, Radboud Alzheimer Center, Donders Institute for Brain, Cognition, and Behavior, Radboud university medical center, Nijmegen, The Netherlands.
Source: PloS one [PLoS One] 2025 Oct 17; Vol. 20 (10), pp. e0333024. Date of Electronic Publication: 2025 Oct 17 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Partial removal of visceral epididymal white adipose tissue in obese Ldlr-/-.Leiden mice impacts adipokine secretion, plasma free fatty acids, and improves cerebrovascular health.
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  Data: <searchLink fieldCode="AU" term="%22Seidel+F%22">Seidel F</searchLink>; Department Medical Imaging, Anatomy, Preclinical Imaging Center, Radboud Alzheimer Center, Donders Institute for Brain, Cognition, and Behavior, Radboud university medical center, Nijmegen, The Netherlands.; Department of Metabolic Health Research, Netherlands Organisation for Applied Scientific Research (TNO), Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Morrison+MC%22">Morrison MC</searchLink>; Department of Metabolic Health Research, Netherlands Organisation for Applied Scientific Research (TNO), Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Arnoldussen+I%22">Arnoldussen I</searchLink>; Department Medical Imaging, Anatomy, Preclinical Imaging Center, Radboud Alzheimer Center, Donders Institute for Brain, Cognition, and Behavior, Radboud university medical center, Nijmegen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Verweij+V%22">Verweij V</searchLink>; Department Medical Imaging, Anatomy, Preclinical Imaging Center, Radboud Alzheimer Center, Donders Institute for Brain, Cognition, and Behavior, Radboud university medical center, Nijmegen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Ebert+S%22">Ebert S</searchLink>; Division of Vascular Biology, Institute for Stroke and Dementia Research (ISD), LMU Klinikum, Ludwig Maximilian University (LMU) Munich, Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Attema+J%22">Attema J</searchLink>; Department of Metabolic Health Research, Netherlands Organisation for Applied Scientific Research (TNO), Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22de+Ruiter+C%22">de Ruiter C</searchLink>; Department of Metabolic Health Research, Netherlands Organisation for Applied Scientific Research (TNO), Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22van+Duyvenvoorde+W%22">van Duyvenvoorde W</searchLink>; Department of Metabolic Health Research, Netherlands Organisation for Applied Scientific Research (TNO), Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Snabel+J%22">Snabel J</searchLink>; Department of Metabolic Health Research, Netherlands Organisation for Applied Scientific Research (TNO), Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Geenen+B%22">Geenen B</searchLink>; Department Medical Imaging, Anatomy, Preclinical Imaging Center, Radboud Alzheimer Center, Donders Institute for Brain, Cognition, and Behavior, Radboud university medical center, Nijmegen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Franco+A%22">Franco A</searchLink>; Department Medical Imaging, Anatomy, Preclinical Imaging Center, Radboud Alzheimer Center, Donders Institute for Brain, Cognition, and Behavior, Radboud university medical center, Nijmegen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Gart+E%22">Gart E</searchLink>; Department of Metabolic Health Research, Netherlands Organisation for Applied Scientific Research (TNO), Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Bernhagen+J%22">Bernhagen J</searchLink>; Division of Vascular Biology, Institute for Stroke and Dementia Research (ISD), LMU Klinikum, Ludwig Maximilian University (LMU) Munich, Munich, Germany.; German Center for Cardiovascular Research (DZHK), partner site Munich Heart Alliance, Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.<br /><searchLink fieldCode="AU" term="%22Wiesmann+M%22">Wiesmann M</searchLink>; Department Medical Imaging, Anatomy, Preclinical Imaging Center, Radboud Alzheimer Center, Donders Institute for Brain, Cognition, and Behavior, Radboud university medical center, Nijmegen, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Kleemann+R%22">Kleemann R</searchLink>; Department of Metabolic Health Research, Netherlands Organisation for Applied Scientific Research (TNO), Leiden, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Kiliaan+AJ%22">Kiliaan AJ</searchLink>; Department Medical Imaging, Anatomy, Preclinical Imaging Center, Radboud Alzheimer Center, Donders Institute for Brain, Cognition, and Behavior, Radboud university medical center, Nijmegen, The Netherlands.
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