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Cooperative role of distinctive TP53 and PTEN combined loss in the peripheral T cell lymphoma-GATA3 molecular subgroup.

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Title: Cooperative role of distinctive TP53 and PTEN combined loss in the peripheral T cell lymphoma-GATA3 molecular subgroup.
Authors: Lone WG; Department of Pathology, Microbiology, and Immunology, University of Nebraska Medical Center, Omaha, NE, USA., Yu J; Department of Pathology, Microbiology, and Immunology, University of Nebraska Medical Center, Omaha, NE, USA., Liu X; Department of Pathology, Microbiology, and Immunology, University of Nebraska Medical Center, Omaha, NE, USA.; Department of Pathology, City of Hope National Medical Center, Duarte, CA, USA., Jochum DT; Department of Pathology, Microbiology, and Immunology, University of Nebraska Medical Center, Omaha, NE, USA., Bouska A; Department of Pathology, Microbiology, and Immunology, University of Nebraska Medical Center, Omaha, NE, USA., Shetty K; Department of Pathology, City of Hope National Medical Center, Duarte, CA, USA., Herek T; Department of Pathology, Microbiology, and Immunology, University of Nebraska Medical Center, Omaha, NE, USA., Sharma S; Department of Pathology, Microbiology, and Immunology, University of Nebraska Medical Center, Omaha, NE, USA., Bi C; Department of Pathology, Microbiology, and Immunology, University of Nebraska Medical Center, Omaha, NE, USA., Shah R; Department of Pathology, Microbiology, and Immunology, University of Nebraska Medical Center, Omaha, NE, USA.; Division of Hematology and Oncology, University of Nebraska Medical Center, Omaha, NE, USA., Nasser ZW; Department of Pathology, Microbiology, and Immunology, University of Nebraska Medical Center, Omaha, NE, USA., Amador C; Department of Pathology, Microbiology, and Immunology, University of Nebraska Medical Center, Omaha, NE, USA.; Department of Pathology, University of Miami, Miami, FL, USA., Arif A; Department of Pathology, Microbiology, and Immunology, University of Nebraska Medical Center, Omaha, NE, USA., Mir AR; Department of Pathology, Microbiology, and Immunology, University of Nebraska Medical Center, Omaha, NE, USA., Li Y; Department of Pathology, City of Hope National Medical Center, Duarte, CA, USA., Heavican-Foral TB; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Robinson J; Department of Biology, University of Nebraska at Omaha, Omaha, NE, USA., Hyde RK; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA., Sakata-Yanagimoto M; Division of Advanced Hemato-Oncology, Transborder Medical Research Center, University of Tsukuba, Tsukuba, Japan., Rachagani S; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA., McKeithan TW; Department of Pathology, City of Hope National Medical Center, Duarte, CA, USA., Scott DW; British Columbia Cancer, Vancouver, BC V5Z 4E6, Canada., Staudt LM; Lymphoid Malignancies Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Inghirami G; Department of Pathology and Laboratory Medicine, Weil Cornell Medical College, New York, NY, USA., Feldman A; Department of Laboratory Medicine and Pathology, Mayo Clinic College of Medicine, Rochester, MN, USA., Greiner T; Department of Pathology, Microbiology, and Immunology, University of Nebraska Medical Center, Omaha, NE, USA., Vose JM; Division of Hematology and Oncology, University of Nebraska Medical Center, Omaha, NE, USA., Rimsza L; Department of Laboratory Medicine and Pathology, Mayo Clinic College of Medicine, Scottsdale, AZ, USA., Khoury J; Department of Pathology, Microbiology, and Immunology, University of Nebraska Medical Center, Omaha, NE, USA., Chan WC; Department of Pathology, City of Hope National Medical Center, Duarte, CA, USA., Iqbal J; Department of Pathology, Microbiology, and Immunology, University of Nebraska Medical Center, Omaha, NE, USA.
Corporate Authors: Lymphoma/Leukemia Molecular Profiling Project (LLMPP)
Source: Science advances [Sci Adv] 2025 Oct 17; Vol. 11 (42), pp. eadx6877. Date of Electronic Publication: 2025 Oct 17.
Publication Type: Journal Article
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2375-2548 (Electronic) Linking ISSN: 23752548 NLM ISO Abbreviation: Sci Adv Subsets: MEDLINE
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Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA.<br /><searchLink fieldCode="AU" term="%22Sakata-Yanagimoto+M%22">Sakata-Yanagimoto M</searchLink>; Division of Advanced Hemato-Oncology, Transborder Medical Research Center, University of Tsukuba, Tsukuba, Japan.<br /><searchLink fieldCode="AU" term="%22Rachagani+S%22">Rachagani S</searchLink>; Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Omaha, NE, USA.<br /><searchLink fieldCode="AU" term="%22McKeithan+TW%22">McKeithan TW</searchLink>; Department of Pathology, City of Hope National Medical Center, Duarte, CA, USA.<br /><searchLink fieldCode="AU" term="%22Scott+DW%22">Scott DW</searchLink>; British Columbia Cancer, Vancouver, BC V5Z 4E6, Canada.<br /><searchLink fieldCode="AU" term="%22Staudt+LM%22">Staudt LM</searchLink>; Lymphoid Malignancies Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.<br /><searchLink fieldCode="AU" term="%22Inghirami+G%22">Inghirami G</searchLink>; 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Department of Pathology, City of Hope National Medical Center, Duarte, CA, USA.<br /><searchLink fieldCode="AU" term="%22Iqbal+J%22">Iqbal J</searchLink>; Department of Pathology, Microbiology, and Immunology, University of Nebraska Medical Center, Omaha, NE, USA.
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