How do particle size, dosage, and exposure duration influence oxidative stress parameters and the in vivo toxicological profile of polydopamine nanoparticles?

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Title: How do particle size, dosage, and exposure duration influence oxidative stress parameters and the in vivo toxicological profile of polydopamine nanoparticles?
Authors: Szukalska M; Laboratory of Environmental Research, Department of Toxicology, Poznan University of Medical Sciences, 3 Rokietnicka Street, Poznań, 60-806, Poland. Electronic address: martan@ump.edu.pl., Mrówczyński R; Faculty of Chemistry, Adam Mickiewicz University, Uniwersytetu Poznańskiego 8, Poznań, 61-614, Poland., Sujka-Kordowska P; Department of Histology and Embryology, Poznan University of Medical Sciences, 6 Święcickiego Street, Poznań, 60-781, Poland., Miechowicz I; Department of Computer Science and Statistics, Poznan University of Medical Sciences, 7 Rokietnicka Street, Poznań, 60-806, Poland., Zalewski T; NanoBioMedical Centre, Adam Mickiewicz University, Wszechnicy Piastowskiej 3, Poznań, 61-614, Poland., Grześkowiak BF; NanoBioMedical Centre, Adam Mickiewicz University, Wszechnicy Piastowskiej 3, Poznań, 61-614, Poland., Bigaj-Józefowska MJ; NanoBioMedical Centre, Adam Mickiewicz University, Wszechnicy Piastowskiej 3, Poznań, 61-614, Poland., Nowicki M; Department of Histology and Embryology, Poznan University of Medical Sciences, 6 Święcickiego Street, Poznań, 60-781, Poland., Florek E; Laboratory of Environmental Research, Department of Toxicology, Poznan University of Medical Sciences, 3 Rokietnicka Street, Poznań, 60-806, Poland.
Source: Free radical biology & medicine [Free Radic Biol Med] 2026 Jan; Vol. 242, pp. 614-635. Date of Electronic Publication: 2025 Oct 15.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Country of Publication: United States NLM ID: 8709159 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4596 (Electronic) Linking ISSN: 08915849 NLM ISO Abbreviation: Free Radic Biol Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1873-4596
DOI:10.1016/j.freeradbiomed.2025.10.265