The twist-and-squeeze activation of CARF-fused adenosine deaminase by cyclic oligoadenylates.

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Title: The twist-and-squeeze activation of CARF-fused adenosine deaminase by cyclic oligoadenylates.
Authors: Whyms C; Department of Chemistry and Biochemistry, Florida State University, Tallahassee, FL, 32306, USA.; Chemistry Department, United States Naval Academy, Annapolis, MD, 21402, USA., Zhao Y; Department of Structural Biology, Van Andel Institute, Grand Rapids, MI, 49503, USA., Addo-Yobo D; Department of Chemistry and Biochemistry, Florida State University, Tallahassee, FL, 32306, USA., He H; Institute of Molecular Biophysics, Florida State University, Tallahassee, FL, 32306, USA., Whittington AC; Department of Biological Sciences, Florida State University, Tallahassee, FL, 32306, USA., Trasanidou D; Laboratory of Microbiology, Wageningen University and Research, Stippeneng 4, 6708WE, Wageningen, The Netherlands.; Sanquin, Postbus 9892, 1006 AN, Amsterdam, The Netherlands., Salazar CRP; Laboratory of Microbiology, Wageningen University and Research, Stippeneng 4, 6708WE, Wageningen, The Netherlands., Staals RHJ; Laboratory of Microbiology, Wageningen University and Research, Stippeneng 4, 6708WE, Wageningen, The Netherlands., Li H; Department of Structural Biology, Van Andel Institute, Grand Rapids, MI, 49503, USA. hong.li@vai.org.
Source: The EMBO journal [EMBO J] 2025 Dec; Vol. 44 (23), pp. 6919-6943. Date of Electronic Publication: 2025 Oct 17.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1460-2075
DOI:10.1038/s44318-025-00578-y