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CRYSTALLBrain: crystalloid fluid choice and neurological outcome in patients with non-traumatic subarachnoid haemorrhage-a study protocol for a multi-centre randomised double-blind clinical trial.

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Title: CRYSTALLBrain: crystalloid fluid choice and neurological outcome in patients with non-traumatic subarachnoid haemorrhage-a study protocol for a multi-centre randomised double-blind clinical trial.
Authors: Messmer AS; Department of Intensive Care Medicine, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland. anna.messmer@insel.ch., Pitteloud M; Department of Intensive Care Medicine, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland., Quintard H; Department of Intensive Care, Neuro-Intensive Care Unit, University Hospital of Geneva, Geneva, Switzerland., Pietsch U; Department of Perioperative Intensive Care Medicine, Cantonal Hospital St. Gallen, St. Gallen, Switzerland.; Department of Emergency Medicine, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland., Müller M; Department of Emergency Medicine, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland., Filipovic M; Department of Perioperative Intensive Care Medicine, Cantonal Hospital St. Gallen, St. Gallen, Switzerland., Jakob SM; University of Bern, Bern, Switzerland., Z'Graggen WJ; Department of Neurosurgery, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland., Schefold JC; Department of Intensive Care Medicine, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland., Pfortmueller CA; Department of Intensive Care Medicine, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland.
Source: Trials [Trials] 2025 Oct 17; Vol. 26 (1), pp. 422. Date of Electronic Publication: 2025 Oct 17.
Publication Type: Journal Article; Clinical Trial Protocol
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101263253 Publication Model: Electronic Cited Medium: Internet ISSN: 1745-6215 (Electronic) Linking ISSN: 17456215 NLM ISO Abbreviation: Trials Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: CRYSTALLBrain: crystalloid fluid choice and neurological outcome in patients with non-traumatic subarachnoid haemorrhage-a study protocol for a multi-centre randomised double-blind clinical trial.
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  Data: <searchLink fieldCode="AU" term="%22Messmer+AS%22">Messmer AS</searchLink>; Department of Intensive Care Medicine, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland. anna.messmer@insel.ch.<br /><searchLink fieldCode="AU" term="%22Pitteloud+M%22">Pitteloud M</searchLink>; Department of Intensive Care Medicine, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland.<br /><searchLink fieldCode="AU" term="%22Quintard+H%22">Quintard H</searchLink>; Department of Intensive Care, Neuro-Intensive Care Unit, University Hospital of Geneva, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Pietsch+U%22">Pietsch U</searchLink>; Department of Perioperative Intensive Care Medicine, Cantonal Hospital St. Gallen, St. Gallen, Switzerland.; Department of Emergency Medicine, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland.<br /><searchLink fieldCode="AU" term="%22Müller+M%22">Müller M</searchLink>; Department of Emergency Medicine, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland.<br /><searchLink fieldCode="AU" term="%22Filipovic+M%22">Filipovic M</searchLink>; Department of Perioperative Intensive Care Medicine, Cantonal Hospital St. Gallen, St. Gallen, Switzerland.<br /><searchLink fieldCode="AU" term="%22Jakob+SM%22">Jakob SM</searchLink>; University of Bern, Bern, Switzerland.<br /><searchLink fieldCode="AU" term="%22Z'Graggen+WJ%22">Z'Graggen WJ</searchLink>; Department of Neurosurgery, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland.<br /><searchLink fieldCode="AU" term="%22Schefold+JC%22">Schefold JC</searchLink>; Department of Intensive Care Medicine, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland.<br /><searchLink fieldCode="AU" term="%22Pfortmueller+CA%22">Pfortmueller CA</searchLink>; Department of Intensive Care Medicine, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland.
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  Data: <searchLink fieldCode="JN" term="%22101263253%22">Trials</searchLink> [Trials] 2025 Oct 17; Vol. 26 (1), pp. 422. <i>Date of Electronic Publication: </i>2025 Oct 17.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101263253 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1745-6215 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217456215%22">17456215 </searchLink><i>NLM ISO Abbreviation: </i>Trials <i>Subsets: </i>MEDLINE
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              Text: 2025 Oct 17
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