G2B: an optimized lentiviral vector with enhanced titer and β-globin expression for improved β-thalassemia gene therapy.
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| Title: | G2B: an optimized lentiviral vector with enhanced titer and β-globin expression for improved β-thalassemia gene therapy. |
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| Authors: | Gao ZY; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China.; Tianjin Institutes of Health Science, Tianjin 301600, China., Yang ZX; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China.; Tianjin Institutes of Health Science, Tianjin 301600, China., Deng DH; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China.; Tianjin Institutes of Health Science, Tianjin 301600, China., Zhang F; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China.; Tianjin Institutes of Health Science, Tianjin 301600, China., Yu B; College of Computer Science and Technology, China University of Petroleum (East China), Qingdao 266000, China., Zhang YY; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China.; Tianjin Institutes of Health Science, Tianjin 301600, China., Lv X; State Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100005, P.R. China., Nakamura Y; Cell Engineering Division, RIKEN BioResource Center, Tsukuba, Ibaraki, Japan., Gong A; College of Computer Science and Technology, China University of Petroleum (East China), Qingdao 266000, China., Cheng T; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China.; Tianjin Institutes of Health Science, Tianjin 301600, China., Zhang JP; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China.; Tianjin Institutes of Health Science, Tianjin 301600, China., Zhang XB; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China.; Tianjin Institutes of Health Science, Tianjin 301600, China. |
| Source: | Blood science (Baltimore, Md.) [Blood Sci] 2025 Oct 15; Vol. 7 (4), pp. e00253. Date of Electronic Publication: 2025 Oct 15 (Print Publication: 2025). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Wolters Kluwer Health, Inc Country of Publication: United States NLM ID: 9918248414306676 Publication Model: eCollection Cited Medium: Internet ISSN: 2543-6368 (Electronic) Linking ISSN: 25436368 NLM ISO Abbreviation: Blood Sci Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41113105 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: G2B: an optimized lentiviral vector with enhanced titer and β-globin expression for improved β-thalassemia gene therapy. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Gao+ZY%22">Gao ZY</searchLink>; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China.; Tianjin Institutes of Health Science, Tianjin 301600, China.<br /><searchLink fieldCode="AU" term="%22Yang+ZX%22">Yang ZX</searchLink>; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China.; Tianjin Institutes of Health Science, Tianjin 301600, China.<br /><searchLink fieldCode="AU" term="%22Deng+DH%22">Deng DH</searchLink>; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China.; Tianjin Institutes of Health Science, Tianjin 301600, China.<br /><searchLink fieldCode="AU" term="%22Zhang+F%22">Zhang F</searchLink>; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China.; Tianjin Institutes of Health Science, Tianjin 301600, China.<br /><searchLink fieldCode="AU" term="%22Yu+B%22">Yu B</searchLink>; College of Computer Science and Technology, China University of Petroleum (East China), Qingdao 266000, China.<br /><searchLink fieldCode="AU" term="%22Zhang+YY%22">Zhang YY</searchLink>; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China.; Tianjin Institutes of Health Science, Tianjin 301600, China.<br /><searchLink fieldCode="AU" term="%22Lv+X%22">Lv X</searchLink>; State Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100005, P.R. China.<br /><searchLink fieldCode="AU" term="%22Nakamura+Y%22">Nakamura Y</searchLink>; Cell Engineering Division, RIKEN BioResource Center, Tsukuba, Ibaraki, Japan.<br /><searchLink fieldCode="AU" term="%22Gong+A%22">Gong A</searchLink>; College of Computer Science and Technology, China University of Petroleum (East China), Qingdao 266000, China.<br /><searchLink fieldCode="AU" term="%22Cheng+T%22">Cheng T</searchLink>; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China.; Tianjin Institutes of Health Science, Tianjin 301600, China.<br /><searchLink fieldCode="AU" term="%22Zhang+JP%22">Zhang JP</searchLink>; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China.; Tianjin Institutes of Health Science, Tianjin 301600, China.<br /><searchLink fieldCode="AU" term="%22Zhang+XB%22">Zhang XB</searchLink>; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China.; Tianjin Institutes of Health Science, Tianjin 301600, China. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%229918248414306676%22">Blood science (Baltimore, Md.)</searchLink> [Blood Sci] 2025 Oct 15; Vol. 7 (4), pp. e00253. <i>Date of Electronic Publication: </i>2025 Oct 15 (<i>Print Publication: </i>2025). – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wolters+Kluwer+Health%2C+Inc%22">Wolters Kluwer Health, Inc </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9918248414306676 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>2543-6368 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2225436368%22">25436368 </searchLink><i>NLM ISO Abbreviation: </i>Blood Sci <i>Subsets: </i>PubMed not MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41113105 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1097/BS9.0000000000000253 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: e00253 Titles: – TitleFull: G2B: an optimized lentiviral vector with enhanced titer and β-globin expression for improved β-thalassemia gene therapy. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Gao ZY – PersonEntity: Name: NameFull: Yang ZX – PersonEntity: Name: NameFull: Deng DH – PersonEntity: Name: NameFull: Zhang F – PersonEntity: Name: NameFull: Yu B – PersonEntity: Name: NameFull: Zhang YY – PersonEntity: Name: NameFull: Lv X – PersonEntity: Name: NameFull: Nakamura Y – PersonEntity: Name: NameFull: Gong A – PersonEntity: Name: NameFull: Cheng T – PersonEntity: Name: NameFull: Zhang JP – PersonEntity: Name: NameFull: Zhang XB IsPartOfRelationships: – BibEntity: Dates: – D: 15 M: 10 Text: 2025 Oct 15 Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 2543-6368 Numbering: – Type: volume Value: 7 – Type: issue Value: 4 Titles: – TitleFull: Blood science (Baltimore, Md.) Type: main |
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