G2B: an optimized lentiviral vector with enhanced titer and β-globin expression for improved β-thalassemia gene therapy.
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| Title: | G2B: an optimized lentiviral vector with enhanced titer and β-globin expression for improved β-thalassemia gene therapy. |
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| Authors: | Gao ZY; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China.; Tianjin Institutes of Health Science, Tianjin 301600, China., Yang ZX; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China.; Tianjin Institutes of Health Science, Tianjin 301600, China., Deng DH; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China.; Tianjin Institutes of Health Science, Tianjin 301600, China., Zhang F; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China.; Tianjin Institutes of Health Science, Tianjin 301600, China., Yu B; College of Computer Science and Technology, China University of Petroleum (East China), Qingdao 266000, China., Zhang YY; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China.; Tianjin Institutes of Health Science, Tianjin 301600, China., Lv X; State Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100005, P.R. China., Nakamura Y; Cell Engineering Division, RIKEN BioResource Center, Tsukuba, Ibaraki, Japan., Gong A; College of Computer Science and Technology, China University of Petroleum (East China), Qingdao 266000, China., Cheng T; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China.; Tianjin Institutes of Health Science, Tianjin 301600, China., Zhang JP; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China.; Tianjin Institutes of Health Science, Tianjin 301600, China., Zhang XB; State Key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Diseases, Haihe Laboratory of Cell Ecosystem, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China.; Tianjin Institutes of Health Science, Tianjin 301600, China. |
| Source: | Blood science (Baltimore, Md.) [Blood Sci] 2025 Oct 15; Vol. 7 (4), pp. e00253. Date of Electronic Publication: 2025 Oct 15 (Print Publication: 2025). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Wolters Kluwer Health, Inc Country of Publication: United States NLM ID: 9918248414306676 Publication Model: eCollection Cited Medium: Internet ISSN: 2543-6368 (Electronic) Linking ISSN: 25436368 NLM ISO Abbreviation: Blood Sci Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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