Prediction of pediatric Wilms tumor recurrence using interpretable machine learning models: insights from a 20-year real-world study and the prognostic value of Ki-67.

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Title: Prediction of pediatric Wilms tumor recurrence using interpretable machine learning models: insights from a 20-year real-world study and the prognostic value of Ki-67.
Authors: Fang H; Department of Urology, Children's Hospital of Chongqing Medical University Chongqing 401122, China.; National Clinical Research Center for Child Health and Disorders Chongqing 401122, China.; Ministry of Education Key Laboratory of Child Development and Disorders Chongqing 401122, China.; Chongqing Key Laboratory of Structural Birth Defect and Reconstruction Chongqing 401122, China., Yu Y; Department of Urology, Children's Hospital of Chongqing Medical University Chongqing 401122, China.; National Clinical Research Center for Child Health and Disorders Chongqing 401122, China.; Ministry of Education Key Laboratory of Child Development and Disorders Chongqing 401122, China.; Chongqing Key Laboratory of Structural Birth Defect and Reconstruction Chongqing 401122, China., Dong J; Department of Urology, Children's Hospital of Chongqing Medical University Chongqing 401122, China.; National Clinical Research Center for Child Health and Disorders Chongqing 401122, China.; Ministry of Education Key Laboratory of Child Development and Disorders Chongqing 401122, China.; Chongqing Key Laboratory of Structural Birth Defect and Reconstruction Chongqing 401122, China., Chen Z; School of Economics and Business Administration, Chongqing University Chongqing 400030, China., Liu F; School of Economics and Business Administration, Chongqing University Chongqing 400030, China., Liu Z; Department of Urology, Jiangxi Children's Medical Center Nanchang 330200, Jiangxi, China., Li Q; School of Finance, Chongqing Technology and Business University Chongqing 400067, China., Liu X; Department of Urology, Children's Hospital of Chongqing Medical University Chongqing 401122, China.; National Clinical Research Center for Child Health and Disorders Chongqing 401122, China.; Ministry of Education Key Laboratory of Child Development and Disorders Chongqing 401122, China.; Chongqing Key Laboratory of Structural Birth Defect and Reconstruction Chongqing 401122, China., Lin T; Department of Urology, Children's Hospital of Chongqing Medical University Chongqing 401122, China.; National Clinical Research Center for Child Health and Disorders Chongqing 401122, China.; Ministry of Education Key Laboratory of Child Development and Disorders Chongqing 401122, China.; Chongqing Key Laboratory of Structural Birth Defect and Reconstruction Chongqing 401122, China., He D; Department of Urology, Children's Hospital of Chongqing Medical University Chongqing 401122, China.; National Clinical Research Center for Child Health and Disorders Chongqing 401122, China.; Ministry of Education Key Laboratory of Child Development and Disorders Chongqing 401122, China.; Chongqing Key Laboratory of Structural Birth Defect and Reconstruction Chongqing 401122, China., Wei G; Department of Urology, Children's Hospital of Chongqing Medical University Chongqing 401122, China.; National Clinical Research Center for Child Health and Disorders Chongqing 401122, China.; Ministry of Education Key Laboratory of Child Development and Disorders Chongqing 401122, China.; Chongqing Key Laboratory of Structural Birth Defect and Reconstruction Chongqing 401122, China., Zhang D; Department of Urology, Children's Hospital of Chongqing Medical University Chongqing 401122, China.; National Clinical Research Center for Child Health and Disorders Chongqing 401122, China.; Ministry of Education Key Laboratory of Child Development and Disorders Chongqing 401122, China.; Chongqing Key Laboratory of Structural Birth Defect and Reconstruction Chongqing 401122, China.
Source: American journal of cancer research [Am J Cancer Res] 2025 Sep 15; Vol. 15 (9), pp. 3835-3853. Date of Electronic Publication: 2025 Sep 15 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: e-Century Pub. Corp Country of Publication: United States NLM ID: 101549944 Publication Model: eCollection Cited Medium: Print ISSN: 2156-6976 (Print) Linking ISSN: 21566976 NLM ISO Abbreviation: Am J Cancer Res Subsets: PubMed not MEDLINE
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  Data: Prediction of pediatric Wilms tumor recurrence using interpretable machine learning models: insights from a 20-year real-world study and the prognostic value of Ki-67.
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  Data: <searchLink fieldCode="AU" term="%22Fang+H%22">Fang H</searchLink>; Department of Urology, Children's Hospital of Chongqing Medical University Chongqing 401122, China.; National Clinical Research Center for Child Health and Disorders Chongqing 401122, China.; Ministry of Education Key Laboratory of Child Development and Disorders Chongqing 401122, China.; Chongqing Key Laboratory of Structural Birth Defect and Reconstruction Chongqing 401122, China.<br /><searchLink fieldCode="AU" term="%22Yu+Y%22">Yu Y</searchLink>; Department of Urology, Children's Hospital of Chongqing Medical University Chongqing 401122, China.; National Clinical Research Center for Child Health and Disorders Chongqing 401122, China.; Ministry of Education Key Laboratory of Child Development and Disorders Chongqing 401122, China.; Chongqing Key Laboratory of Structural Birth Defect and Reconstruction Chongqing 401122, China.<br /><searchLink fieldCode="AU" term="%22Dong+J%22">Dong J</searchLink>; Department of Urology, Children's Hospital of Chongqing Medical University Chongqing 401122, China.; National Clinical Research Center for Child Health and Disorders Chongqing 401122, China.; Ministry of Education Key Laboratory of Child Development and Disorders Chongqing 401122, China.; Chongqing Key Laboratory of Structural Birth Defect and Reconstruction Chongqing 401122, China.<br /><searchLink fieldCode="AU" term="%22Chen+Z%22">Chen Z</searchLink>; School of Economics and Business Administration, Chongqing University Chongqing 400030, China.<br /><searchLink fieldCode="AU" term="%22Liu+F%22">Liu F</searchLink>; School of Economics and Business Administration, Chongqing University Chongqing 400030, China.<br /><searchLink fieldCode="AU" term="%22Liu+Z%22">Liu Z</searchLink>; Department of Urology, Jiangxi Children's Medical Center Nanchang 330200, Jiangxi, China.<br /><searchLink fieldCode="AU" term="%22Li+Q%22">Li Q</searchLink>; School of Finance, Chongqing Technology and Business University Chongqing 400067, China.<br /><searchLink fieldCode="AU" term="%22Liu+X%22">Liu X</searchLink>; Department of Urology, Children's Hospital of Chongqing Medical University Chongqing 401122, China.; National Clinical Research Center for Child Health and Disorders Chongqing 401122, China.; Ministry of Education Key Laboratory of Child Development and Disorders Chongqing 401122, China.; Chongqing Key Laboratory of Structural Birth Defect and Reconstruction Chongqing 401122, China.<br /><searchLink fieldCode="AU" term="%22Lin+T%22">Lin T</searchLink>; Department of Urology, Children's Hospital of Chongqing Medical University Chongqing 401122, China.; National Clinical Research Center for Child Health and Disorders Chongqing 401122, China.; Ministry of Education Key Laboratory of Child Development and Disorders Chongqing 401122, China.; Chongqing Key Laboratory of Structural Birth Defect and Reconstruction Chongqing 401122, China.<br /><searchLink fieldCode="AU" term="%22He+D%22">He D</searchLink>; Department of Urology, Children's Hospital of Chongqing Medical University Chongqing 401122, China.; National Clinical Research Center for Child Health and Disorders Chongqing 401122, China.; Ministry of Education Key Laboratory of Child Development and Disorders Chongqing 401122, China.; Chongqing Key Laboratory of Structural Birth Defect and Reconstruction Chongqing 401122, China.<br /><searchLink fieldCode="AU" term="%22Wei+G%22">Wei G</searchLink>; Department of Urology, Children's Hospital of Chongqing Medical University Chongqing 401122, China.; National Clinical Research Center for Child Health and Disorders Chongqing 401122, China.; Ministry of Education Key Laboratory of Child Development and Disorders Chongqing 401122, China.; Chongqing Key Laboratory of Structural Birth Defect and Reconstruction Chongqing 401122, China.<br /><searchLink fieldCode="AU" term="%22Zhang+D%22">Zhang D</searchLink>; Department of Urology, Children's Hospital of Chongqing Medical University Chongqing 401122, China.; National Clinical Research Center for Child Health and Disorders Chongqing 401122, China.; Ministry of Education Key Laboratory of Child Development and Disorders Chongqing 401122, China.; Chongqing Key Laboratory of Structural Birth Defect and Reconstruction Chongqing 401122, China.
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  Data: <searchLink fieldCode="JN" term="%22101549944%22">American journal of cancer research</searchLink> [Am J Cancer Res] 2025 Sep 15; Vol. 15 (9), pp. 3835-3853. <i>Date of Electronic Publication: </i>2025 Sep 15 (<i>Print Publication: </i>2025).
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        Value: 10.62347/GLJC3405
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      – TitleFull: Prediction of pediatric Wilms tumor recurrence using interpretable machine learning models: insights from a 20-year real-world study and the prognostic value of Ki-67.
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