View in EDS

Heme and hemozoin induce platelet cell death through UPR-induced apoptosis and ferroptosis in vivax malaria.

Saved in:
Bibliographic Details
Title: Heme and hemozoin induce platelet cell death through UPR-induced apoptosis and ferroptosis in vivax malaria.
Authors: Gomes MT; Laboratory of Immunothrombosis, Department of Biochemistry, Institute of Biological Sciences, Federal University of Juiz de Fora, Juiz de Fora, Brazil.; Programa de Pós-graduação em Ciências Biológicas, Institute of Biological Sciences, Federal University of Juiz de Fora, Juiz de Fora, Brazil., Medeiros-de-Moraes IM; Laboratory of Immunopharmacology, Oswald Cruz Institute, Oswald Cruz Foundation, Rio de Janeiro, Brazil., Vieira-de-Abreu A; Laboratory of Immunopharmacology, Oswald Cruz Institute, Oswald Cruz Foundation, Rio de Janeiro, Brazil.; Department of Internal Medicine and Molecular Medicine Program, University of Utah, Salt Lake City, UT., de Azevedo-Quintanilha IG; Laboratory of Immunopharmacology, Oswald Cruz Institute, Oswald Cruz Foundation, Rio de Janeiro, Brazil., Fontes TM; Laboratory of Immunothrombosis, Department of Biochemistry, Institute of Biological Sciences, Federal University of Juiz de Fora, Juiz de Fora, Brazil.; Programa de Pós-graduação em Ciências Biológicas, Institute of Biological Sciences, Federal University of Juiz de Fora, Juiz de Fora, Brazil., de Brito Carneiro A; Laboratory of Immunopharmacology, Oswald Cruz Institute, Oswald Cruz Foundation, Rio de Janeiro, Brazil.; Department of Surgery, College of Medicine, University of Illinois at Chicago, Chicago, IL., Azambuja P; Laboratory of Clinical Research in Intensive Care Medicine, National Institute of Infectious Diseases Evandro Chagas, Fiocruz, Rio de Janeiro, Brazil., Tolley ND; Department of Internal Medicine and Molecular Medicine Program, University of Utah, Salt Lake City, UT., Rowley JW; Department of Internal Medicine and Molecular Medicine Program, University of Utah, Salt Lake City, UT., Carpinter BA; Programa de Pós-graduação em Ciências Biológicas, Institute of Biological Sciences, Federal University of Juiz de Fora, Juiz de Fora, Brazil.; Department of Parasitology, Microbiology and Immunology, Institute of Biological Sciences, Federal University of Juiz de Fora, Juiz de Fora, Brazil., Ferreira MU; Department of Parasitology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.; Associate Laboratory in Translation and Innovation Towards Global Health, Department of Global Health and Tropical Medicine, Institute of Hygiene and Tropical Medicine, NOVA University of Lisbon, Lisbon, Portugal., Gonçalves RM; Department of Parasitology, Microbiology and Immunology, Institute of Biological Sciences, Federal University of Juiz de Fora, Juiz de Fora, Brazil., Rocha VN; Laboratory of Veterinary Pathology and Histology, Department of Veterinary Medicine, Faculty of Medicine, Federal University of Juiz de Fora, Juiz de Fora, Brazil., Rosa Nascimento AL; Laboratory of Ultrastructure and Tissue, Department of Histology and Embryology, State University of Rio de Janeiro, Rio de Janeiro, Brazil., Carvalho WA; Laboratory of Animal Health, Embrapa Gado de Leite, Juiz de Fora, Brazil., Scopel KKG; Department of Parasitology, Microbiology and Immunology, Institute of Biological Sciences, Federal University of Juiz de Fora, Juiz de Fora, Brazil., Campbell RA; Department of Emergency Medicine, Washington University, St Louis, MO., Bozza PT; Programa de Pós-graduação em Ciências Biológicas, Institute of Biological Sciences, Federal University of Juiz de Fora, Juiz de Fora, Brazil., Weyrich AS; Department of Internal Medicine and Molecular Medicine Program, University of Utah, Salt Lake City, UT., Zimmerman GA; Department of Internal Medicine and Molecular Medicine Program, University of Utah, Salt Lake City, UT., Lacerda MVG; Fundação de Medicina Tropical Dr Heitor Vieira Dourado, Manaus, Brazil.; Instituto Leônidas & Maria Deane, Fiocruz, Manaus, Brazil.; Department of Pathology, The University of Texas Medical Branch, Galveston, TX., Castro-Faria-Neto HC; Laboratory of Immunopharmacology, Oswald Cruz Institute, Oswald Cruz Foundation, Rio de Janeiro, Brazil., Hottz ED; Laboratory of Immunothrombosis, Department of Biochemistry, Institute of Biological Sciences, Federal University of Juiz de Fora, Juiz de Fora, Brazil.
Source: Blood advances [Blood Adv] 2026 Feb 10; Vol. 10 (3), pp. 575-592.
Publication Type: Journal Article
Journal Info: Publisher: American Society of Hematology Country of Publication: United States NLM ID: 101698425 Publication Model: Print Cited Medium: Internet ISSN: 2473-9537 (Electronic) Linking ISSN: 24739529 NLM ISO Abbreviation: Blood Adv Subsets: MEDLINE
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 41115249
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Heme and hemozoin induce platelet cell death through UPR-induced apoptosis and ferroptosis in vivax malaria.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Gomes+MT%22">Gomes MT</searchLink>; Laboratory of Immunothrombosis, Department of Biochemistry, Institute of Biological Sciences, Federal University of Juiz de Fora, Juiz de Fora, Brazil.; Programa de Pós-graduação em Ciências Biológicas, Institute of Biological Sciences, Federal University of Juiz de Fora, Juiz de Fora, Brazil.<br /><searchLink fieldCode="AU" term="%22Medeiros-de-Moraes+IM%22">Medeiros-de-Moraes IM</searchLink>; Laboratory of Immunopharmacology, Oswald Cruz Institute, Oswald Cruz Foundation, Rio de Janeiro, Brazil.<br /><searchLink fieldCode="AU" term="%22Vieira-de-Abreu+A%22">Vieira-de-Abreu A</searchLink>; Laboratory of Immunopharmacology, Oswald Cruz Institute, Oswald Cruz Foundation, Rio de Janeiro, Brazil.; Department of Internal Medicine and Molecular Medicine Program, University of Utah, Salt Lake City, UT.<br /><searchLink fieldCode="AU" term="%22de+Azevedo-Quintanilha+IG%22">de Azevedo-Quintanilha IG</searchLink>; Laboratory of Immunopharmacology, Oswald Cruz Institute, Oswald Cruz Foundation, Rio de Janeiro, Brazil.<br /><searchLink fieldCode="AU" term="%22Fontes+TM%22">Fontes TM</searchLink>; Laboratory of Immunothrombosis, Department of Biochemistry, Institute of Biological Sciences, Federal University of Juiz de Fora, Juiz de Fora, Brazil.; Programa de Pós-graduação em Ciências Biológicas, Institute of Biological Sciences, Federal University of Juiz de Fora, Juiz de Fora, Brazil.<br /><searchLink fieldCode="AU" term="%22de+Brito+Carneiro+A%22">de Brito Carneiro A</searchLink>; Laboratory of Immunopharmacology, Oswald Cruz Institute, Oswald Cruz Foundation, Rio de Janeiro, Brazil.; Department of Surgery, College of Medicine, University of Illinois at Chicago, Chicago, IL.<br /><searchLink fieldCode="AU" term="%22Azambuja+P%22">Azambuja P</searchLink>; Laboratory of Clinical Research in Intensive Care Medicine, National Institute of Infectious Diseases Evandro Chagas, Fiocruz, Rio de Janeiro, Brazil.<br /><searchLink fieldCode="AU" term="%22Tolley+ND%22">Tolley ND</searchLink>; Department of Internal Medicine and Molecular Medicine Program, University of Utah, Salt Lake City, UT.<br /><searchLink fieldCode="AU" term="%22Rowley+JW%22">Rowley JW</searchLink>; Department of Internal Medicine and Molecular Medicine Program, University of Utah, Salt Lake City, UT.<br /><searchLink fieldCode="AU" term="%22Carpinter+BA%22">Carpinter BA</searchLink>; Programa de Pós-graduação em Ciências Biológicas, Institute of Biological Sciences, Federal University of Juiz de Fora, Juiz de Fora, Brazil.; Department of Parasitology, Microbiology and Immunology, Institute of Biological Sciences, Federal University of Juiz de Fora, Juiz de Fora, Brazil.<br /><searchLink fieldCode="AU" term="%22Ferreira+MU%22">Ferreira MU</searchLink>; Department of Parasitology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil.; Associate Laboratory in Translation and Innovation Towards Global Health, Department of Global Health and Tropical Medicine, Institute of Hygiene and Tropical Medicine, NOVA University of Lisbon, Lisbon, Portugal.<br /><searchLink fieldCode="AU" term="%22Gonçalves+RM%22">Gonçalves RM</searchLink>; Department of Parasitology, Microbiology and Immunology, Institute of Biological Sciences, Federal University of Juiz de Fora, Juiz de Fora, Brazil.<br /><searchLink fieldCode="AU" term="%22Rocha+VN%22">Rocha VN</searchLink>; Laboratory of Veterinary Pathology and Histology, Department of Veterinary Medicine, Faculty of Medicine, Federal University of Juiz de Fora, Juiz de Fora, Brazil.<br /><searchLink fieldCode="AU" term="%22Rosa+Nascimento+AL%22">Rosa Nascimento AL</searchLink>; Laboratory of Ultrastructure and Tissue, Department of Histology and Embryology, State University of Rio de Janeiro, Rio de Janeiro, Brazil.<br /><searchLink fieldCode="AU" term="%22Carvalho+WA%22">Carvalho WA</searchLink>; Laboratory of Animal Health, Embrapa Gado de Leite, Juiz de Fora, Brazil.<br /><searchLink fieldCode="AU" term="%22Scopel+KKG%22">Scopel KKG</searchLink>; Department of Parasitology, Microbiology and Immunology, Institute of Biological Sciences, Federal University of Juiz de Fora, Juiz de Fora, Brazil.<br /><searchLink fieldCode="AU" term="%22Campbell+RA%22">Campbell RA</searchLink>; Department of Emergency Medicine, Washington University, St Louis, MO.<br /><searchLink fieldCode="AU" term="%22Bozza+PT%22">Bozza PT</searchLink>; Programa de Pós-graduação em Ciências Biológicas, Institute of Biological Sciences, Federal University of Juiz de Fora, Juiz de Fora, Brazil.<br /><searchLink fieldCode="AU" term="%22Weyrich+AS%22">Weyrich AS</searchLink>; Department of Internal Medicine and Molecular Medicine Program, University of Utah, Salt Lake City, UT.<br /><searchLink fieldCode="AU" term="%22Zimmerman+GA%22">Zimmerman GA</searchLink>; Department of Internal Medicine and Molecular Medicine Program, University of Utah, Salt Lake City, UT.<br /><searchLink fieldCode="AU" term="%22Lacerda+MVG%22">Lacerda MVG</searchLink>; Fundação de Medicina Tropical Dr Heitor Vieira Dourado, Manaus, Brazil.; Instituto Leônidas & Maria Deane, Fiocruz, Manaus, Brazil.; Department of Pathology, The University of Texas Medical Branch, Galveston, TX.<br /><searchLink fieldCode="AU" term="%22Castro-Faria-Neto+HC%22">Castro-Faria-Neto HC</searchLink>; Laboratory of Immunopharmacology, Oswald Cruz Institute, Oswald Cruz Foundation, Rio de Janeiro, Brazil.<br /><searchLink fieldCode="AU" term="%22Hottz+ED%22">Hottz ED</searchLink>; Laboratory of Immunothrombosis, Department of Biochemistry, Institute of Biological Sciences, Federal University of Juiz de Fora, Juiz de Fora, Brazil.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101698425%22">Blood advances</searchLink> [Blood Adv] 2026 Feb 10; Vol. 10 (3), pp. 575-592.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Society+of+Hematology%22">American Society of Hematology </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101698425 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>2473-9537 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2224739529%22">24739529 </searchLink><i>NLM ISO Abbreviation: </i>Blood Adv <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41115249
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1182/bloodadvances.2024015623
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: 575
    Titles:
      – TitleFull: Heme and hemozoin induce platelet cell death through UPR-induced apoptosis and ferroptosis in vivax malaria.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Gomes MT
      – PersonEntity:
          Name:
            NameFull: Medeiros-de-Moraes IM
      – PersonEntity:
          Name:
            NameFull: Vieira-de-Abreu A
      – PersonEntity:
          Name:
            NameFull: de Azevedo-Quintanilha IG
      – PersonEntity:
          Name:
            NameFull: Fontes TM
      – PersonEntity:
          Name:
            NameFull: de Brito Carneiro A
      – PersonEntity:
          Name:
            NameFull: Azambuja P
      – PersonEntity:
          Name:
            NameFull: Tolley ND
      – PersonEntity:
          Name:
            NameFull: Rowley JW
      – PersonEntity:
          Name:
            NameFull: Carpinter BA
      – PersonEntity:
          Name:
            NameFull: Ferreira MU
      – PersonEntity:
          Name:
            NameFull: Gonçalves RM
      – PersonEntity:
          Name:
            NameFull: Rocha VN
      – PersonEntity:
          Name:
            NameFull: Rosa Nascimento AL
      – PersonEntity:
          Name:
            NameFull: Carvalho WA
      – PersonEntity:
          Name:
            NameFull: Scopel KKG
      – PersonEntity:
          Name:
            NameFull: Campbell RA
      – PersonEntity:
          Name:
            NameFull: Bozza PT
      – PersonEntity:
          Name:
            NameFull: Weyrich AS
      – PersonEntity:
          Name:
            NameFull: Zimmerman GA
      – PersonEntity:
          Name:
            NameFull: Lacerda MVG
      – PersonEntity:
          Name:
            NameFull: Castro-Faria-Neto HC
      – PersonEntity:
          Name:
            NameFull: Hottz ED
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 10
              M: 02
              Text: 2026 Feb 10
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 2473-9537
          Numbering:
            – Type: volume
              Value: 10
            – Type: issue
              Value: 3
          Titles:
            – TitleFull: Blood advances
              Type: main
ResultId 1