Chemotherapy-Treated Breast Cancer Cells Activate the WNT Signaling Pathway to Enter a Diapause-Like Early Persister State.

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Title: Chemotherapy-Treated Breast Cancer Cells Activate the WNT Signaling Pathway to Enter a Diapause-Like Early Persister State.
Authors: El Laithy Y; Department of Development and Regeneration, Stem Cell Institute, KU Leuven, Leuven, Belgium., Abreu De Oliveira WA; Department of Development and Regeneration, Stem Cell Institute, KU Leuven, Leuven, Belgium., Pabba A; Department of Oncology, Laboratory for Translational Breast Cancer Research, KU Leuven, Leuven, Belgium., Qualizza A; Department of Development and Regeneration, Stem Cell Institute, KU Leuven, Leuven, Belgium., Cosemans G; Department of Development and Regeneration, Stem Cell Institute, KU Leuven, Leuven, Belgium., Garcia-Diaz P; Department of Development and Regeneration, Stem Cell Institute, KU Leuven, Leuven, Belgium., Richard F; Department of Oncology, Laboratory for Translational Breast Cancer Research, KU Leuven, Leuven, Belgium., Athanasouli P; Department of Development and Regeneration, Stem Cell Institute, KU Leuven, Leuven, Belgium., Rios Luci C; Department of Imaging and Pathology, NanoHealth and Optical Imaging Group, KU Leuven, Leuven, Belgium., De Wispelaere W; Gynecological Oncology, Department of Oncology, KU Leuven, Leuven, Belgium., Mourao L; Laboratory of Intravital Microscopy and Dynamics of Tumor Progression, Department of Oncology, VIB-KU Leuven Center for Cancer Biology, Leuven, Belgium., Hamer S; Preclinical Modelling of Pediatric Cancer Evolution, Institute of Cancer Research (ICR), London, United Kingdom., Moens S; Gynecological Oncology, Department of Oncology, KU Leuven, Leuven, Belgium., De Jaime-Soguero A; Department of Development and Regeneration, Stem Cell Institute, KU Leuven, Leuven, Belgium., Baietti MF; TRACE - Laboratory for RNA Cancer Biology, Department of Oncology, KU Leuven, Leuven, Belgium., Hutten SJ; Division of Molecular Pathology, The Netherlands Cancer Institute, Amsterdam, the Netherlands.; Oncode Institute, Amsterdam, the Netherlands., Jonkers J; Division of Molecular Pathology, The Netherlands Cancer Institute, Amsterdam, the Netherlands.; Oncode Institute, Amsterdam, the Netherlands., Sammut SJ; Breast Cancer Now Toby Robins Research Centre, Institute of Cancer Research (ICR), London, United Kingdom.; The Royal Marsden Hospital, NHS Foundation Trust, London, United Kingdom., Soenen S; Department of Imaging and Pathology, NanoHealth and Optical Imaging Group, KU Leuven, Leuven, Belgium., Scheele CLGJ; Laboratory of Intravital Microscopy and Dynamics of Tumor Progression, Department of Oncology, VIB-KU Leuven Center for Cancer Biology, Leuven, Belgium., Bruna A; Preclinical Modelling of Pediatric Cancer Evolution, Institute of Cancer Research (ICR), London, United Kingdom., Desmedt C; Department of Oncology, Laboratory for Translational Breast Cancer Research, KU Leuven, Leuven, Belgium., Annibali D; Gynecological Oncology, Department of Oncology, KU Leuven, Leuven, Belgium., Lluis F; Department of Development and Regeneration, Stem Cell Institute, KU Leuven, Leuven, Belgium.
Source: Cancer research [Cancer Res] 2026 Jan 16; Vol. 86 (2), pp. 310-330.
Publication Type: Journal Article
Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1538-7445
DOI:10.1158/0008-5472.CAN-24-4165