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Effectiveness of a Digital Therapy on 6-Month Weight Loss in People With Obesity: The Digital Therapy to Promote Weight Loss in Patients With Obesity by Increasing Their Adherence to Treatment (DEMETRA) Randomized Clinical Trial.

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Title: Effectiveness of a Digital Therapy on 6-Month Weight Loss in People With Obesity: The Digital Therapy to Promote Weight Loss in Patients With Obesity by Increasing Their Adherence to Treatment (DEMETRA) Randomized Clinical Trial.
Authors: Bertoli S; Obesity Center and Research Lab on Nutrition and Obesity, IRCCS Istituto Auxologico Italiano, Milan, Italy.; Department of Food, Environmental and Nutritional Sciences (DeFENS), University of Milan, Milan, Italy., Capodaglio P; Musculoskeletal and Metabolic Rehabilitation Unit, IRCCS Istituto Auxologico Italiano, Milan, Italy.; Department of Biomedical, Surgical and Dentistry Sciences, University of Milan, Milan, Italy., Colosimo S; Obesity Center and Research Lab on Nutrition and Obesity, IRCCS Istituto Auxologico Italiano, Milan, Italy.; Department of Food, Environmental and Nutritional Sciences (DeFENS), University of Milan, Milan, Italy., De Amicis RS; Obesity Center and Research Lab on Nutrition and Obesity, IRCCS Istituto Auxologico Italiano, Milan, Italy.; Department of Food, Environmental and Nutritional Sciences (DeFENS), University of Milan, Milan, Italy., Gilardini L; Obesity Center and Research Lab on Nutrition and Obesity, IRCCS Istituto Auxologico Italiano, Milan, Italy., Bruno A; Obesity Center and Research Lab on Nutrition and Obesity, IRCCS Istituto Auxologico Italiano, Milan, Italy., Mambrini SP; Obesity Center and Research Lab on Nutrition and Obesity, IRCCS Istituto Auxologico Italiano, Milan, Italy., Pietrabissa G; Clinical Psychology Research Lab, Piancavallo, IRCCS Istituto Auxologico Italiano, Milan, Italy.; Department of Psychology, Catholic University of Milan, Milan, Italy., Cavaggioni L; Obesity Center and Research Lab on Nutrition and Obesity, IRCCS Istituto Auxologico Italiano, Milan, Italy.; Department of Biotechnology and Life Sciences, University of Insubria, Varese, Italy., Castelnuovo G; Clinical Psychology Research Lab, Piancavallo, IRCCS Istituto Auxologico Italiano, Milan, Italy.; Department of Psychology, Catholic University of Milan, Milan, Italy., Piazzolla G; University of Bari Aldo Moro, Bari, Italy.
Source: Journal of medical Internet research [J Med Internet Res] 2025 Oct 21; Vol. 27, pp. e72054. Date of Electronic Publication: 2025 Oct 21.
Publication Type: Journal Article; Randomized Controlled Trial; Multicenter Study; Pragmatic Clinical Trial
Journal Info: Publisher: JMIR Publications Country of Publication: Canada NLM ID: 100959882 Publication Model: Electronic Cited Medium: Internet ISSN: 1438-8871 (Electronic) Linking ISSN: 14388871 NLM ISO Abbreviation: J Med Internet Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Bertoli+S%22">Bertoli S</searchLink>; Obesity Center and Research Lab on Nutrition and Obesity, IRCCS Istituto Auxologico Italiano, Milan, Italy.; Department of Food, Environmental and Nutritional Sciences (DeFENS), University of Milan, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Capodaglio+P%22">Capodaglio P</searchLink>; Musculoskeletal and Metabolic Rehabilitation Unit, IRCCS Istituto Auxologico Italiano, Milan, Italy.; Department of Biomedical, Surgical and Dentistry Sciences, University of Milan, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Colosimo+S%22">Colosimo S</searchLink>; Obesity Center and Research Lab on Nutrition and Obesity, IRCCS Istituto Auxologico Italiano, Milan, Italy.; Department of Food, Environmental and Nutritional Sciences (DeFENS), University of Milan, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22De+Amicis+RS%22">De Amicis RS</searchLink>; Obesity Center and Research Lab on Nutrition and Obesity, IRCCS Istituto Auxologico Italiano, Milan, Italy.; Department of Food, Environmental and Nutritional Sciences (DeFENS), University of Milan, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Gilardini+L%22">Gilardini L</searchLink>; Obesity Center and Research Lab on Nutrition and Obesity, IRCCS Istituto Auxologico Italiano, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Bruno+A%22">Bruno A</searchLink>; Obesity Center and Research Lab on Nutrition and Obesity, IRCCS Istituto Auxologico Italiano, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Mambrini+SP%22">Mambrini SP</searchLink>; Obesity Center and Research Lab on Nutrition and Obesity, IRCCS Istituto Auxologico Italiano, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Pietrabissa+G%22">Pietrabissa G</searchLink>; Clinical Psychology Research Lab, Piancavallo, IRCCS Istituto Auxologico Italiano, Milan, Italy.; Department of Psychology, Catholic University of Milan, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Cavaggioni+L%22">Cavaggioni L</searchLink>; Obesity Center and Research Lab on Nutrition and Obesity, IRCCS Istituto Auxologico Italiano, Milan, Italy.; Department of Biotechnology and Life Sciences, University of Insubria, Varese, Italy.<br /><searchLink fieldCode="AU" term="%22Castelnuovo+G%22">Castelnuovo G</searchLink>; Clinical Psychology Research Lab, Piancavallo, IRCCS Istituto Auxologico Italiano, Milan, Italy.; Department of Psychology, Catholic University of Milan, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Piazzolla+G%22">Piazzolla G</searchLink>; University of Bari Aldo Moro, Bari, Italy.
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