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Capivasertib plus abiraterone in PTEN-deficient metastatic hormone-sensitive prostate cancer: CAPItello-281 phase III study.

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Title: Capivasertib plus abiraterone in PTEN-deficient metastatic hormone-sensitive prostate cancer: CAPItello-281 phase III study.
Authors: Fizazi K; Department of Cancer Medicine, Institut Gustave Roussy, Centre Oscar Lambret, University of Paris Saclay, Villejuif, France. Electronic address: k-fizazi@o-lambret.fr., Clarke NW; The Christie and Salford Royal NHS Foundation Trusts, University of Manchester, Manchester, UK., De Santis M; Charite Universitätsmedizin Berlin, Berlin, Germany; Medical University of Vienna, Vienna, Austria., Uemura H; Kindai University Hospital, Osaka, Japan., Fay AP; Hospital Nora Teixeira and PUCRS School of Medicine, Porto Alegre, Brazil., Karadurmus N; SBU Gulhane Training and Research Hospital, Ankara, Turkey., Kwiatkowski M; Szpital Wojewódzki w Koszalinie, Koszalin, Poland., Alvarez-Fernandez C; Hospital Universitario Central de Asturias, Oviedo, Spain; Instituto de Investigación Sanitaria del Principado de Asturias, Oviedo, Spain., Jiang S; Hunan Cancer Hospital, Hunan, China., Sotelo M; Hospital Maria Auxiliadora, Lima, Peru., Parslow D; Derriford Hospital, Plymouth, UK., Oliveira N; Mater Hospital Brisbane, Mater Misericordiae Ltd, Brisbane, Australia; Mater Clinical Unit, School of Clinical Medicine, The University of Queensland, Brisbane, Australia., Kwon TG; Kyungpook National University Chilgok Hospital, Daegu, South Korea., Ye D; Fudan University Shanghai Cancer Center, Shanghai, China., Boudewijns S; Bravis Ziekenhuis, Roosendaal, The Netherlands., Danchaivijitr P; Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand., Rooney C; AstraZeneca, Cambridge, UK., Gresty C; AstraZeneca, Cambridge, UK., Yeste-Velasco M; AstraZeneca, Barcelona, Spain., Logan J; AstraZeneca, Gaithersburg, USA., George DJ; Duke University Cancer Institute, Durham, USA.
Corporate Authors: CAPItello-281 Study Group
Source: Annals of oncology : official journal of the European Society for Medical Oncology [Ann Oncol] 2026 Jan; Vol. 37 (1), pp. 53-68. Date of Electronic Publication: 2025 Oct 19.
Publication Type: Journal Article; Clinical Trial, Phase III; Randomized Controlled Trial; Multicenter Study
Journal Info: Publisher: Elsevier Country of Publication: England NLM ID: 9007735 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1569-8041 (Electronic) Linking ISSN: 09237534 NLM ISO Abbreviation: Ann Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Capivasertib plus abiraterone in PTEN-deficient metastatic hormone-sensitive prostate cancer: CAPItello-281 phase III study.
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  Data: <searchLink fieldCode="AU" term="%22Fizazi+K%22">Fizazi K</searchLink>; Department of Cancer Medicine, Institut Gustave Roussy, Centre Oscar Lambret, University of Paris Saclay, Villejuif, France. Electronic address: k-fizazi@o-lambret.fr.<br /><searchLink fieldCode="AU" term="%22Clarke+NW%22">Clarke NW</searchLink>; The Christie and Salford Royal NHS Foundation Trusts, University of Manchester, Manchester, UK.<br /><searchLink fieldCode="AU" term="%22De+Santis+M%22">De Santis M</searchLink>; Charite Universitätsmedizin Berlin, Berlin, Germany; Medical University of Vienna, Vienna, Austria.<br /><searchLink fieldCode="AU" term="%22Uemura+H%22">Uemura H</searchLink>; Kindai University Hospital, Osaka, Japan.<br /><searchLink fieldCode="AU" term="%22Fay+AP%22">Fay AP</searchLink>; Hospital Nora Teixeira and PUCRS School of Medicine, Porto Alegre, Brazil.<br /><searchLink fieldCode="AU" term="%22Karadurmus+N%22">Karadurmus N</searchLink>; SBU Gulhane Training and Research Hospital, Ankara, Turkey.<br /><searchLink fieldCode="AU" term="%22Kwiatkowski+M%22">Kwiatkowski M</searchLink>; Szpital Wojewódzki w Koszalinie, Koszalin, Poland.<br /><searchLink fieldCode="AU" term="%22Alvarez-Fernandez+C%22">Alvarez-Fernandez C</searchLink>; Hospital Universitario Central de Asturias, Oviedo, Spain; Instituto de Investigación Sanitaria del Principado de Asturias, Oviedo, Spain.<br /><searchLink fieldCode="AU" term="%22Jiang+S%22">Jiang S</searchLink>; Hunan Cancer Hospital, Hunan, China.<br /><searchLink fieldCode="AU" term="%22Sotelo+M%22">Sotelo M</searchLink>; Hospital Maria Auxiliadora, Lima, Peru.<br /><searchLink fieldCode="AU" term="%22Parslow+D%22">Parslow D</searchLink>; Derriford Hospital, Plymouth, UK.<br /><searchLink fieldCode="AU" term="%22Oliveira+N%22">Oliveira N</searchLink>; Mater Hospital Brisbane, Mater Misericordiae Ltd, Brisbane, Australia; Mater Clinical Unit, School of Clinical Medicine, The University of Queensland, Brisbane, Australia.<br /><searchLink fieldCode="AU" term="%22Kwon+TG%22">Kwon TG</searchLink>; Kyungpook National University Chilgok Hospital, Daegu, South Korea.<br /><searchLink fieldCode="AU" term="%22Ye+D%22">Ye D</searchLink>; Fudan University Shanghai Cancer Center, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Boudewijns+S%22">Boudewijns S</searchLink>; Bravis Ziekenhuis, Roosendaal, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Danchaivijitr+P%22">Danchaivijitr P</searchLink>; Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand.<br /><searchLink fieldCode="AU" term="%22Rooney+C%22">Rooney C</searchLink>; AstraZeneca, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Gresty+C%22">Gresty C</searchLink>; AstraZeneca, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Yeste-Velasco+M%22">Yeste-Velasco M</searchLink>; AstraZeneca, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Logan+J%22">Logan J</searchLink>; AstraZeneca, Gaithersburg, USA.<br /><searchLink fieldCode="AU" term="%22George+DJ%22">George DJ</searchLink>; Duke University Cancer Institute, Durham, USA.
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  Data: <searchLink fieldCode="JN" term="%229007735%22">Annals of oncology : official journal of the European Society for Medical Oncology</searchLink> [Ann Oncol] 2026 Jan; Vol. 37 (1), pp. 53-68. <i>Date of Electronic Publication: </i>2025 Oct 19.
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  Data: Journal Article; Clinical Trial, Phase III; Randomized Controlled Trial; Multicenter Study
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9007735 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1569-8041 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2209237534%22">09237534 </searchLink><i>NLM ISO Abbreviation: </i>Ann Oncol <i>Subsets: </i>MEDLINE
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              Text: 2026 Jan
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