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ZC3H4, a novel regulator of mitochondrial complex I, impacts prostate stromal cell senescence, attachment, adhesion and anoikis resistance.

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Title: ZC3H4, a novel regulator of mitochondrial complex I, impacts prostate stromal cell senescence, attachment, adhesion and anoikis resistance.
Authors: Liu TT; Department of Urology, University of Wisconsin, Madison, WI, USA., Carrarini MJ; Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Department of Biological Sciences, Carnegie Mellon University, Pittsburgh, PA, USA., Myklebust LK; Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Molecular Genetics and Developmental Biology Graduate Program, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Skalitzky KO; Department of Urology, University of Wisconsin, Madison, WI, USA.; Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., El-Khoury N; Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Sipula IJ; Department of Medicine, Division of Endocrinology and Metabolism, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Chang A; Department of Biomedical Informatics, University of Pittsburgh, Pittsburgh, PA, USA., Soman V; Department of Biomedical Informatics, University of Pittsburgh, Pittsburgh, PA, USA., Liu A; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Ihejirika N; Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Chandran UR; Department of Biomedical Informatics, University of Pittsburgh, Pittsburgh, PA, USA., Jurczak MJ; Department of Medicine, Division of Endocrinology and Metabolism, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Ricke WA; Department of Urology, University of Wisconsin, Madison, WI, USA., DeFranco DB; Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Pittsburgh Institute for Neurodegenerative Diseases, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Pascal LE; Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. lep44@pitt.edu.; UPMC Hillman Cancer Center, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. lep44@pitt.edu.
Source: Cell death & disease [Cell Death Dis] 2025 Oct 21; Vol. 16 (1), pp. 741. Date of Electronic Publication: 2025 Oct 21.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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