Clinical and cost-effectiveness of flexor digitorum profundus (FDP) versus FDP and flexor digitorum superficialis (FDS) repair for complete zone 2 flexor tendon injuries (FLARE): protocol for a randomised controlled trial.
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| Title: | Clinical and cost-effectiveness of flexor digitorum profundus (FDP) versus FDP and flexor digitorum superficialis (FDS) repair for complete zone 2 flexor tendon injuries (FLARE): protocol for a randomised controlled trial. |
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| Authors: | Reay E; South Tees Academic Centre for Surgery, The James Cook University Hospital, Marton Road, Middlesbrough, TS4 3BW, UK., Adamson J; York Trials Unit, Department of Health Sciences, Faculty of Science, University of York, York, YO10 5DD, UK., Newington L; Barts Bone and Joint Health, Blizard Institute, Queen Mary University of London, 4 Newark Street, London, E1 2AT, UK., Baird K; York Trials Unit, Department of Health Sciences, Faculty of Science, University of York, York, YO10 5DD, UK., Wiggins F; York Trials Unit, Department of Health Sciences, Faculty of Science, University of York, York, YO10 5DD, UK., Glerum-Brooks K; York Trials Unit, Department of Health Sciences, Faculty of Science, University of York, York, YO10 5DD, UK., Cook L; York Trials Unit, Department of Health Sciences, Faculty of Science, University of York, York, YO10 5DD, UK., Hewison A; York Trials Unit, Department of Health Sciences, Faculty of Science, University of York, York, YO10 5DD, UK., Hewitt C; York Trials Unit, Department of Health Sciences, Faculty of Science, University of York, York, YO10 5DD, UK., Hira S; Frimley Health NHS Foundation Trust, Wexham Park Hospital, Wexham Street, Slough, Berkshire, SL2 4HL, UK., Holmes D; Wirral University Teaching Hospital NHS Foundation Trust, Arrowe Park Hospital, Arrowe Park Road, Birkenhead, Wirral, CH49 5PE, UK., Kottam L; South Tees Academic Centre for Surgery, The James Cook University Hospital, Marton Road, Middlesbrough, TS4 3BW, UK., Lane JCE; Barts Bone and Joint Health, Blizard Institute, Queen Mary University of London, 4 Newark Street, London, E1 2AT, UK., Li J; York Trials Unit, Department of Health Sciences, Faculty of Science, University of York, York, YO10 5DD, UK., Mandefield L; York Trials Unit, Department of Health Sciences, Faculty of Science, University of York, York, YO10 5DD, UK., Moatt E; York Trials Unit, Department of Health Sciences, Faculty of Science, University of York, York, YO10 5DD, UK., Parrott S; York Trials Unit, Department of Health Sciences, Faculty of Science, University of York, York, YO10 5DD, UK., Rangan A; South Tees Academic Centre for Surgery, The James Cook University Hospital, Marton Road, Middlesbrough, TS4 3BW, UK.; York Trials Unit, Department of Health Sciences, Faculty of Science, University of York, York, YO10 5DD, UK., Rodrigues J; Warwick Clinical Trials Unit, Warwick Medical School, University of Warwick, Coventry, CV4 7AL, UK., Scantlebury A; York Trials Unit, Department of Health Sciences, Faculty of Science, University of York, York, YO10 5DD, UK., Wade RG; Leeds Institute for Medical Research, University of Leeds, Leeds, LS9 7TF, UK., Watson M; York Trials Unit, Department of Health Sciences, Faculty of Science, University of York, York, YO10 5DD, UK., Wormald JCR; Surgical Interventional Trials Unit, Nuffield, Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences , Botnar Research Centre, Old Road, Headington, Oxford, OX3 7LD, UK.; Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS), Oxford Trauma and Emergency Care, Kadoorie CentreUniversity of OxfordJohn Radcliffe Hospital, Level 3Headley Way, NuffieldOxford, OX3 9DU, UK., Gardiner MD; Surgical Interventional Trials Unit, Nuffield, Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences , Botnar Research Centre, Old Road, Headington, Oxford, OX3 7LD, UK. matthew.gardiner@nhs.net.; Frimley Health NHS Foundation Trust, Wexham Park Hospital, Wexham Street, Slough, Berkshire, SL2 4HL, UK. matthew.gardiner@nhs.net. |
| Source: | Trials [Trials] 2025 Oct 21; Vol. 26 (1), pp. 424. Date of Electronic Publication: 2025 Oct 21. |
| Publication Type: | Journal Article; Clinical Trial Protocol |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 101263253 Publication Model: Electronic Cited Medium: Internet ISSN: 1745-6215 (Electronic) Linking ISSN: 17456215 NLM ISO Abbreviation: Trials Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41121267 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Clinical and cost-effectiveness of flexor digitorum profundus (FDP) versus FDP and flexor digitorum superficialis (FDS) repair for complete zone 2 flexor tendon injuries (FLARE): protocol for a randomised controlled trial. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Reay+E%22">Reay E</searchLink>; South Tees Academic Centre for Surgery, The James Cook University Hospital, Marton Road, Middlesbrough, TS4 3BW, UK.<br /><searchLink fieldCode="AU" term="%22Adamson+J%22">Adamson J</searchLink>; York Trials Unit, Department of Health Sciences, Faculty of Science, University of York, York, YO10 5DD, UK.<br /><searchLink fieldCode="AU" term="%22Newington+L%22">Newington L</searchLink>; Barts Bone and Joint Health, Blizard Institute, Queen Mary University of London, 4 Newark Street, London, E1 2AT, UK.<br /><searchLink fieldCode="AU" term="%22Baird+K%22">Baird K</searchLink>; York Trials Unit, Department of Health Sciences, Faculty of Science, University of York, York, YO10 5DD, UK.<br /><searchLink fieldCode="AU" term="%22Wiggins+F%22">Wiggins F</searchLink>; York Trials Unit, Department of Health Sciences, Faculty of Science, University of York, York, YO10 5DD, UK.<br /><searchLink fieldCode="AU" term="%22Glerum-Brooks+K%22">Glerum-Brooks K</searchLink>; York Trials Unit, Department of Health Sciences, Faculty of Science, University of York, York, YO10 5DD, UK.<br /><searchLink fieldCode="AU" term="%22Cook+L%22">Cook L</searchLink>; York Trials Unit, Department of Health Sciences, Faculty of Science, University of York, York, YO10 5DD, UK.<br /><searchLink fieldCode="AU" term="%22Hewison+A%22">Hewison A</searchLink>; York Trials Unit, Department of Health Sciences, Faculty of Science, University of York, York, YO10 5DD, UK.<br /><searchLink fieldCode="AU" term="%22Hewitt+C%22">Hewitt C</searchLink>; York Trials Unit, Department of Health Sciences, Faculty of Science, University of York, York, YO10 5DD, UK.<br /><searchLink fieldCode="AU" term="%22Hira+S%22">Hira S</searchLink>; Frimley Health NHS Foundation Trust, Wexham Park Hospital, Wexham Street, Slough, Berkshire, SL2 4HL, UK.<br /><searchLink fieldCode="AU" term="%22Holmes+D%22">Holmes D</searchLink>; Wirral University Teaching Hospital NHS Foundation Trust, Arrowe Park Hospital, Arrowe Park Road, Birkenhead, Wirral, CH49 5PE, UK.<br /><searchLink fieldCode="AU" term="%22Kottam+L%22">Kottam L</searchLink>; South Tees Academic Centre for Surgery, The James Cook University Hospital, Marton Road, Middlesbrough, TS4 3BW, UK.<br /><searchLink fieldCode="AU" term="%22Lane+JCE%22">Lane JCE</searchLink>; Barts Bone and Joint Health, Blizard Institute, Queen Mary University of London, 4 Newark Street, London, E1 2AT, UK.<br /><searchLink fieldCode="AU" term="%22Li+J%22">Li J</searchLink>; York Trials Unit, Department of Health Sciences, Faculty of Science, University of York, York, YO10 5DD, UK.<br /><searchLink fieldCode="AU" term="%22Mandefield+L%22">Mandefield L</searchLink>; York Trials Unit, Department of Health Sciences, Faculty of Science, University of York, York, YO10 5DD, UK.<br /><searchLink fieldCode="AU" term="%22Moatt+E%22">Moatt E</searchLink>; York Trials Unit, Department of Health Sciences, Faculty of Science, University of York, York, YO10 5DD, UK.<br /><searchLink fieldCode="AU" term="%22Parrott+S%22">Parrott S</searchLink>; York Trials Unit, Department of Health Sciences, Faculty of Science, University of York, York, YO10 5DD, UK.<br /><searchLink fieldCode="AU" term="%22Rangan+A%22">Rangan A</searchLink>; South Tees Academic Centre for Surgery, The James Cook University Hospital, Marton Road, Middlesbrough, TS4 3BW, UK.; York Trials Unit, Department of Health Sciences, Faculty of Science, University of York, York, YO10 5DD, UK.<br /><searchLink fieldCode="AU" term="%22Rodrigues+J%22">Rodrigues J</searchLink>; Warwick Clinical Trials Unit, Warwick Medical School, University of Warwick, Coventry, CV4 7AL, UK.<br /><searchLink fieldCode="AU" term="%22Scantlebury+A%22">Scantlebury A</searchLink>; York Trials Unit, Department of Health Sciences, Faculty of Science, University of York, York, YO10 5DD, UK.<br /><searchLink fieldCode="AU" term="%22Wade+RG%22">Wade RG</searchLink>; Leeds Institute for Medical Research, University of Leeds, Leeds, LS9 7TF, UK.<br /><searchLink fieldCode="AU" term="%22Watson+M%22">Watson M</searchLink>; York Trials Unit, Department of Health Sciences, Faculty of Science, University of York, York, YO10 5DD, UK.<br /><searchLink fieldCode="AU" term="%22Wormald+JCR%22">Wormald JCR</searchLink>; Surgical Interventional Trials Unit, Nuffield, Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences , Botnar Research Centre, Old Road, Headington, Oxford, OX3 7LD, UK.; Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS), Oxford Trauma and Emergency Care, Kadoorie CentreUniversity of OxfordJohn Radcliffe Hospital, Level 3Headley Way, NuffieldOxford, OX3 9DU, UK.<br /><searchLink fieldCode="AU" term="%22Gardiner+MD%22">Gardiner MD</searchLink>; Surgical Interventional Trials Unit, Nuffield, Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences , Botnar Research Centre, Old Road, Headington, Oxford, OX3 7LD, UK. matthew.gardiner@nhs.net.; Frimley Health NHS Foundation Trust, Wexham Park Hospital, Wexham Street, Slough, Berkshire, SL2 4HL, UK. matthew.gardiner@nhs.net. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101263253%22">Trials</searchLink> [Trials] 2025 Oct 21; Vol. 26 (1), pp. 424. <i>Date of Electronic Publication: </i>2025 Oct 21. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Clinical Trial Protocol – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101263253 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1745-6215 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2217456215%22">17456215 </searchLink><i>NLM ISO Abbreviation: </i>Trials <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41121267 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1186/s13063-025-09043-x Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 424 Titles: – TitleFull: Clinical and cost-effectiveness of flexor digitorum profundus (FDP) versus FDP and flexor digitorum superficialis (FDS) repair for complete zone 2 flexor tendon injuries (FLARE): protocol for a randomised controlled trial. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Reay E – PersonEntity: Name: NameFull: Adamson J – PersonEntity: Name: NameFull: Newington L – PersonEntity: Name: NameFull: Baird K – PersonEntity: Name: NameFull: Wiggins F – PersonEntity: Name: NameFull: Glerum-Brooks K – PersonEntity: Name: NameFull: Cook L – PersonEntity: Name: NameFull: Hewison A – PersonEntity: Name: NameFull: Hewitt C – PersonEntity: Name: NameFull: Hira S – PersonEntity: Name: NameFull: Holmes D – PersonEntity: Name: NameFull: Kottam L – PersonEntity: Name: NameFull: Lane JCE – PersonEntity: Name: NameFull: Li J – PersonEntity: Name: NameFull: Mandefield L – PersonEntity: Name: NameFull: Moatt E – PersonEntity: Name: NameFull: Parrott S – PersonEntity: Name: NameFull: Rangan A – PersonEntity: Name: NameFull: Rodrigues J – PersonEntity: Name: NameFull: Scantlebury A – PersonEntity: Name: NameFull: Wade RG – PersonEntity: Name: NameFull: Watson M – PersonEntity: Name: NameFull: Wormald JCR – PersonEntity: Name: NameFull: Gardiner MD IsPartOfRelationships: – BibEntity: Dates: – D: 21 M: 10 Text: 2025 Oct 21 Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 1745-6215 Numbering: – Type: volume Value: 26 – Type: issue Value: 1 Titles: – TitleFull: Trials Type: main |
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