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Current landscape of T-cell engagers in early-phase clinical development in solid cancers.

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Title: Current landscape of T-cell engagers in early-phase clinical development in solid cancers.
Authors: Spinazzola A; Phase 1 Unit, Fondazione Policlinico Universitario A. Gemelli, Istituto di ricovero e cura a carattere scientifico (IRCCS), Rome, Italy., Iannantuono GM; Phase 1 Unit, Fondazione Policlinico Universitario A. Gemelli, Istituto di ricovero e cura a carattere scientifico (IRCCS), Rome, Italy., Gulley JL; Center for Immuno-Oncology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, United States., Giudice E; Division of Gynecologic Oncology, Humanitas San Pio X, Milan, Italy., Filetti M; Phase 1 Unit, Fondazione Policlinico Universitario A. Gemelli, Istituto di ricovero e cura a carattere scientifico (IRCCS), Rome, Italy., Sganga S; Phase 1 Unit, Fondazione Policlinico Universitario A. Gemelli, Istituto di ricovero e cura a carattere scientifico (IRCCS), Rome, Italy., Bianco FL; Phase 1 Unit, Fondazione Policlinico Universitario A. Gemelli, Istituto di ricovero e cura a carattere scientifico (IRCCS), Rome, Italy., Floudas CS; Center for Immuno-Oncology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, United States., Daniele G; Phase 1 Unit, Fondazione Policlinico Universitario A. Gemelli, Istituto di ricovero e cura a carattere scientifico (IRCCS), Rome, Italy.
Source: Frontiers in immunology [Front Immunol] 2025 Oct 06; Vol. 16, pp. 1665838. Date of Electronic Publication: 2025 Oct 06 (Print Publication: 2025).
Publication Type: Journal Article; Review
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1664-3224
DOI:10.3389/fimmu.2025.1665838