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Synergistic Cancer Metabolic Therapy via Co-Delivery of 3-Bromopyruvate and Temozolomide with a Supramolecular Shuttle.

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Title: Synergistic Cancer Metabolic Therapy via Co-Delivery of 3-Bromopyruvate and Temozolomide with a Supramolecular Shuttle.
Authors: Bellavita R; Department of Pharmacy, School of Medicine, University of Naples Federico II, Via Domenico Montesano 49, 80131 Napoli, Italy., Prisco M; Department of Biology,University of Napoli Federico II, Via Cintia, 80126 Naples, Italy., Palladino S; Department of Pharmacy, School of Medicine, University of Naples Federico II, Via Domenico Montesano 49, 80131 Napoli, Italy., Barra T; Department of Pharmacy, School of Medicine, University of Naples Federico II, Via Domenico Montesano 49, 80131 Napoli, Italy.; Department of Biology,University of Napoli Federico II, Via Cintia, 80126 Naples, Italy., Donadio F; Institute of Applied Sciences and Intelligent Systems (ISASI), Naples Cryo Electron Microscopy Laboratory - EYE LAB, National Research Council (CNR), Via Pietro Castellino 111, 80131 Naples, Italy., Esposito E; Institute of Applied Sciences and Intelligent Systems (ISASI), Naples Cryo Electron Microscopy Laboratory - EYE LAB, National Research Council (CNR), Via Pietro Castellino 111, 80131 Naples, Italy., Esposito R; Department of Chemical Sciences, University of Napoli Federico II, and CSGI (Unit of Naples), Via Cintia, 80126 Naples, Italy., Panico G; Department of Biology,University of Napoli Federico II, Via Cintia, 80126 Naples, Italy., Pisano J; Department of Biology,University of Napoli Federico II, Via Cintia, 80126 Naples, Italy., Venditti P; Department of Biology,University of Napoli Federico II, Via Cintia, 80126 Naples, Italy., Valiante S; Department of Biology,University of Napoli Federico II, Via Cintia, 80126 Naples, Italy., Falanga A; Department of Agricultural Sciences, University of Naples Federico II, Via Università 100, 80055 Portici, Italy., D'Errico G; Department of Chemical Sciences, University of Napoli Federico II, and CSGI (Unit of Naples), Via Cintia, 80126 Naples, Italy., Lombardi A; Department of Biology,University of Napoli Federico II, Via Cintia, 80126 Naples, Italy., Galdiero S; Department of Pharmacy, School of Medicine, University of Naples Federico II, Via Domenico Montesano 49, 80131 Napoli, Italy.
Source: ACS applied materials & interfaces [ACS Appl Mater Interfaces] 2025 Nov 05; Vol. 17 (44), pp. 60342-60360. Date of Electronic Publication: 2025 Oct 22.
Publication Type: Journal Article
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101504991 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1944-8252 (Electronic) Linking ISSN: 19448244 NLM ISO Abbreviation: ACS Appl Mater Interfaces Subsets: MEDLINE
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  Data: Synergistic Cancer Metabolic Therapy via Co-Delivery of 3-Bromopyruvate and Temozolomide with a Supramolecular Shuttle.
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  Data: <searchLink fieldCode="AU" term="%22Bellavita+R%22">Bellavita R</searchLink>; Department of Pharmacy, School of Medicine, University of Naples Federico II, Via Domenico Montesano 49, 80131 Napoli, Italy.<br /><searchLink fieldCode="AU" term="%22Prisco+M%22">Prisco M</searchLink>; Department of Biology,University of Napoli Federico II, Via Cintia, 80126 Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Palladino+S%22">Palladino S</searchLink>; Department of Pharmacy, School of Medicine, University of Naples Federico II, Via Domenico Montesano 49, 80131 Napoli, Italy.<br /><searchLink fieldCode="AU" term="%22Barra+T%22">Barra T</searchLink>; Department of Pharmacy, School of Medicine, University of Naples Federico II, Via Domenico Montesano 49, 80131 Napoli, Italy.; Department of Biology,University of Napoli Federico II, Via Cintia, 80126 Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Donadio+F%22">Donadio F</searchLink>; Institute of Applied Sciences and Intelligent Systems (ISASI), Naples Cryo Electron Microscopy Laboratory - EYE LAB, National Research Council (CNR), Via Pietro Castellino 111, 80131 Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Esposito+E%22">Esposito E</searchLink>; Institute of Applied Sciences and Intelligent Systems (ISASI), Naples Cryo Electron Microscopy Laboratory - EYE LAB, National Research Council (CNR), Via Pietro Castellino 111, 80131 Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Esposito+R%22">Esposito R</searchLink>; Department of Chemical Sciences, University of Napoli Federico II, and CSGI (Unit of Naples), Via Cintia, 80126 Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Panico+G%22">Panico G</searchLink>; Department of Biology,University of Napoli Federico II, Via Cintia, 80126 Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Pisano+J%22">Pisano J</searchLink>; Department of Biology,University of Napoli Federico II, Via Cintia, 80126 Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Venditti+P%22">Venditti P</searchLink>; Department of Biology,University of Napoli Federico II, Via Cintia, 80126 Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Valiante+S%22">Valiante S</searchLink>; Department of Biology,University of Napoli Federico II, Via Cintia, 80126 Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Falanga+A%22">Falanga A</searchLink>; Department of Agricultural Sciences, University of Naples Federico II, Via Università 100, 80055 Portici, Italy.<br /><searchLink fieldCode="AU" term="%22D'Errico+G%22">D'Errico G</searchLink>; Department of Chemical Sciences, University of Napoli Federico II, and CSGI (Unit of Naples), Via Cintia, 80126 Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Lombardi+A%22">Lombardi A</searchLink>; Department of Biology,University of Napoli Federico II, Via Cintia, 80126 Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Galdiero+S%22">Galdiero S</searchLink>; Department of Pharmacy, School of Medicine, University of Naples Federico II, Via Domenico Montesano 49, 80131 Napoli, Italy.
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  Data: <searchLink fieldCode="JN" term="%22101504991%22">ACS applied materials & interfaces</searchLink> [ACS Appl Mater Interfaces] 2025 Nov 05; Vol. 17 (44), pp. 60342-60360. <i>Date of Electronic Publication: </i>2025 Oct 22.
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