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Development of a Real-Time Fluorescence-Based Deamination Assay and Identification of Inhibitors of Human Cytidine Deaminase.

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Title: Development of a Real-Time Fluorescence-Based Deamination Assay and Identification of Inhibitors of Human Cytidine Deaminase.
Authors: Moorthy R; Department of Medicinal Chemistry, University of Minnesota, Minneapolis, Minnesota 55455, United States., Grillo MJ; Department of Medicinal Chemistry, University of Minnesota, Minneapolis, Minnesota 55455, United States., Baur JW; Department of Chemistry, University of Minnesota, Minneapolis, Minnesota 55455, United States., Schmidt SA; Department of Chemistry, University of Minnesota, Minneapolis, Minnesota 55455, United States., Passow KT; Department of Medicinal Chemistry, University of Minnesota, Minneapolis, Minnesota 55455, United States., Demir Ö; Department of Molecular Biology, University of California - San Diego, La Jolla, California 92093, United States., Tang J; Department of Medicinal Chemistry, University of Minnesota, Minneapolis, Minnesota 55455, United States., Olson ME; Department of Medicinal Chemistry, University of Minnesota, Minneapolis, Minnesota 55455, United States., Amaro RE; Department of Molecular Biology, University of California - San Diego, La Jolla, California 92093, United States., Harki DA; Department of Medicinal Chemistry, University of Minnesota, Minneapolis, Minnesota 55455, United States.; Department of Chemistry, University of Minnesota, Minneapolis, Minnesota 55455, United States.
Source: ACS chemical biology [ACS Chem Biol] 2025 Nov 21; Vol. 20 (11), pp. 2593-2600. Date of Electronic Publication: 2025 Oct 22.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101282906 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1554-8937 (Electronic) Linking ISSN: 15548929 NLM ISO Abbreviation: ACS Chem Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Development of a Real-Time Fluorescence-Based Deamination Assay and Identification of Inhibitors of Human Cytidine Deaminase.
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  Data: <searchLink fieldCode="AU" term="%22Moorthy+R%22">Moorthy R</searchLink>; Department of Medicinal Chemistry, University of Minnesota, Minneapolis, Minnesota 55455, United States.<br /><searchLink fieldCode="AU" term="%22Grillo+MJ%22">Grillo MJ</searchLink>; Department of Medicinal Chemistry, University of Minnesota, Minneapolis, Minnesota 55455, United States.<br /><searchLink fieldCode="AU" term="%22Baur+JW%22">Baur JW</searchLink>; Department of Chemistry, University of Minnesota, Minneapolis, Minnesota 55455, United States.<br /><searchLink fieldCode="AU" term="%22Schmidt+SA%22">Schmidt SA</searchLink>; Department of Chemistry, University of Minnesota, Minneapolis, Minnesota 55455, United States.<br /><searchLink fieldCode="AU" term="%22Passow+KT%22">Passow KT</searchLink>; Department of Medicinal Chemistry, University of Minnesota, Minneapolis, Minnesota 55455, United States.<br /><searchLink fieldCode="AU" term="%22Demir+Ö%22">Demir Ö</searchLink>; Department of Molecular Biology, University of California - San Diego, La Jolla, California 92093, United States.<br /><searchLink fieldCode="AU" term="%22Tang+J%22">Tang J</searchLink>; Department of Medicinal Chemistry, University of Minnesota, Minneapolis, Minnesota 55455, United States.<br /><searchLink fieldCode="AU" term="%22Olson+ME%22">Olson ME</searchLink>; Department of Medicinal Chemistry, University of Minnesota, Minneapolis, Minnesota 55455, United States.<br /><searchLink fieldCode="AU" term="%22Amaro+RE%22">Amaro RE</searchLink>; Department of Molecular Biology, University of California - San Diego, La Jolla, California 92093, United States.<br /><searchLink fieldCode="AU" term="%22Harki+DA%22">Harki DA</searchLink>; Department of Medicinal Chemistry, University of Minnesota, Minneapolis, Minnesota 55455, United States.; Department of Chemistry, University of Minnesota, Minneapolis, Minnesota 55455, United States.
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  Data: <searchLink fieldCode="JN" term="%22101282906%22">ACS chemical biology</searchLink> [ACS Chem Biol] 2025 Nov 21; Vol. 20 (11), pp. 2593-2600. <i>Date of Electronic Publication: </i>2025 Oct 22.
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        Value: 10.1021/acschembio.5c00394
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              Text: 2025 Nov 21
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