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Genome-wide association study of childhood B-cell acute lymphoblastic leukemia reveals novel African ancestry-specific susceptibility loci.

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Title: Genome-wide association study of childhood B-cell acute lymphoblastic leukemia reveals novel African ancestry-specific susceptibility loci.
Authors: Im C; Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA. imcindy@umn.edu., Raduski AR; Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA., Mills LJ; Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA., Bhattarai KR; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA., Mobley RJ; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA., Barnett KR; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA., Lu Z; Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA., Liao K; Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA., Anderson N; Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA., Johnson RA; Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA., Langer E; Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA., Hooten AJ; Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA., Seif AE; Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA, USA., Bernt KM; Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA, USA., Tsang M; Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA, USA., Mamou BA; Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, PA, USA., Gil-de-Gómez L; Department of Molecular Biology, University of Cantabria-IDIVAL, Santander, Cantabria, Spain., Wolfson JA; Institute for Cancer Outcomes and Survivorship, University of Alabama at Birmingham, Birmingham, AL, USA., Friedman DN; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Shukla N; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Klesse LJ; Harold C. Simmons Comprehensive Cancer Center and the Department of Pediatrics, University of Texas Southwestern Medical School, Dallas, TX, USA., Marcotte EL; Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA., Ji L; Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA., Dang A; Children's Oncology Group, Monrovia, CA, USA., Luo M; Division of Genomic Diagnostics, Children's Hospital of Philadelphia, Philadelphia, PA, USA., Zhong Y; Division of Genomic Diagnostics, Children's Hospital of Philadelphia, Philadelphia, PA, USA., Langie J; Center for Genetic Epidemiology, Department of Population and Public Health Sciences, University of Southern California Keck School of Medicine, Los Angeles, CA, USA., Chiang CWK; Center for Genetic Epidemiology, Department of Population and Public Health Sciences, University of Southern California Keck School of Medicine, Los Angeles, CA, USA., de Smith A; Center for Genetic Epidemiology, Department of Population and Public Health Sciences, University of Southern California Keck School of Medicine, Los Angeles, CA, USA., Wiemels JL; Center for Genetic Epidemiology, Department of Population and Public Health Sciences, University of Southern California Keck School of Medicine, Los Angeles, CA, USA., DeWan A; Department of Chronic Disease Epidemiology, Yale School of Public Health, New Haven, CT, USA., Ma X; Department of Chronic Disease Epidemiology, Yale School of Public Health, New Haven, CT, USA., Metayer C; School of Public Health, University of California, Berkeley, CA, USA., Wang Z; Department of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, TN, USA., Nelson HH; Division of Epidemiology and Community Health, University of Minnesota, Minneapolis, MN, USA., Pankratz N; Department of Laboratory Medicine and Pathology, School of Medicine, University of Minnesota, Minneapolis, MN, USA., Yang T; Division of Biostatistics and Health Data Science, School of Public Health, University of Minnesota, Minneapolis, MN, USA., Basu S; Division of Biostatistics and Health Data Science, School of Public Health, University of Minnesota, Minneapolis, MN, USA., Turcotte LM; Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA., Yang JJ; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA., Savic D; Department of Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, USA., Scheurer ME; Department of Pediatrics, Section of Hematology-Oncology, Baylor College of Medicine, Houston, TX, USA.; Texas Children's Cancer and Hematology Center, Texas Children's Hospital, Houston, TX, USA., Spector LG; Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA. spect012@umn.edu.
Source: Nature communications [Nat Commun] 2025 Oct 22; Vol. 16 (1), pp. 8974. Date of Electronic Publication: 2025 Oct 22.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Genome-wide association study of childhood B-cell acute lymphoblastic leukemia reveals novel African ancestry-specific susceptibility loci.
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