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Structural mechanism of the agonist binding on human TRPC3 channel.

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Title: Structural mechanism of the agonist binding on human TRPC3 channel.
Authors: Chen Y; State Key Laboratory of Membrane Biology, College of Future Technology, Institute of Molecular Medicine, Peking University, Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Beijing, China.; Academy for Advanced Interdisciplinary Studies, Peking University, Beijing, China., Zang J; State Key Laboratory of Membrane Biology, College of Future Technology, Institute of Molecular Medicine, Peking University, Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Beijing, China., Guo W; State Key Laboratory of Membrane Biology, College of Future Technology, Institute of Molecular Medicine, Peking University, Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Beijing, China.; Academy for Advanced Interdisciplinary Studies, Peking University, Beijing, China.; Peking-Tsinghua Center for Life Sciences, Peking University, Beijing, China., Xu J; State Key Laboratory of Membrane Biology, College of Future Technology, Institute of Molecular Medicine, Peking University, Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Beijing, China., Wei M; State Key Laboratory of Membrane Biology, College of Future Technology, Institute of Molecular Medicine, Peking University, Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Beijing, China., Quan L; State Key Laboratory of Membrane Biology, College of Future Technology, Institute of Molecular Medicine, Peking University, Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Beijing, China., Zhu M; Shanghai Novamab Biopharmaceuticals Co, Ltd, Shanghai, China., Zhao X; Center for Nanochemistry, Beijing Science and Engineering Center for Nanocarbons, Beijing National Laboratory for Molecular Sciences, College of Chemistry and Molecular Engineering, Peking University, Beijing, China., Peng H; Center for Nanochemistry, Beijing Science and Engineering Center for Nanocarbons, Beijing National Laboratory for Molecular Sciences, College of Chemistry and Molecular Engineering, Peking University, Beijing, China., Wan Y; Shanghai Novamab Biopharmaceuticals Co, Ltd, Shanghai, China., Chen L; State Key Laboratory of Membrane Biology, College of Future Technology, Institute of Molecular Medicine, Peking University, Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Beijing, China. chenlei2016@pku.edu.cn.; Academy for Advanced Interdisciplinary Studies, Peking University, Beijing, China. chenlei2016@pku.edu.cn.; Peking-Tsinghua Center for Life Sciences, Peking University, Beijing, China. chenlei2016@pku.edu.cn.; National Biomedical Imaging Center, Peking University, Beijing, China. chenlei2016@pku.edu.cn.
Source: Nature communications [Nat Commun] 2025 Oct 22; Vol. 16 (1), pp. 9343. Date of Electronic Publication: 2025 Oct 22.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Chen+Y%22">Chen Y</searchLink>; State Key Laboratory of Membrane Biology, College of Future Technology, Institute of Molecular Medicine, Peking University, Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Beijing, China.; Academy for Advanced Interdisciplinary Studies, Peking University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Zang+J%22">Zang J</searchLink>; State Key Laboratory of Membrane Biology, College of Future Technology, Institute of Molecular Medicine, Peking University, Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Guo+W%22">Guo W</searchLink>; State Key Laboratory of Membrane Biology, College of Future Technology, Institute of Molecular Medicine, Peking University, Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Beijing, China.; Academy for Advanced Interdisciplinary Studies, Peking University, Beijing, China.; Peking-Tsinghua Center for Life Sciences, Peking University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Xu+J%22">Xu J</searchLink>; State Key Laboratory of Membrane Biology, College of Future Technology, Institute of Molecular Medicine, Peking University, Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Wei+M%22">Wei M</searchLink>; State Key Laboratory of Membrane Biology, College of Future Technology, Institute of Molecular Medicine, Peking University, Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Quan+L%22">Quan L</searchLink>; State Key Laboratory of Membrane Biology, College of Future Technology, Institute of Molecular Medicine, Peking University, Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Zhu+M%22">Zhu M</searchLink>; Shanghai Novamab Biopharmaceuticals Co, Ltd, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Zhao+X%22">Zhao X</searchLink>; Center for Nanochemistry, Beijing Science and Engineering Center for Nanocarbons, Beijing National Laboratory for Molecular Sciences, College of Chemistry and Molecular Engineering, Peking University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Peng+H%22">Peng H</searchLink>; Center for Nanochemistry, Beijing Science and Engineering Center for Nanocarbons, Beijing National Laboratory for Molecular Sciences, College of Chemistry and Molecular Engineering, Peking University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Wan+Y%22">Wan Y</searchLink>; Shanghai Novamab Biopharmaceuticals Co, Ltd, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Chen+L%22">Chen L</searchLink>; State Key Laboratory of Membrane Biology, College of Future Technology, Institute of Molecular Medicine, Peking University, Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Beijing, China. chenlei2016@pku.edu.cn.; Academy for Advanced Interdisciplinary Studies, Peking University, Beijing, China. chenlei2016@pku.edu.cn.; Peking-Tsinghua Center for Life Sciences, Peking University, Beijing, China. chenlei2016@pku.edu.cn.; National Biomedical Imaging Center, Peking University, Beijing, China. chenlei2016@pku.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2025 Oct 22; Vol. 16 (1), pp. 9343. <i>Date of Electronic Publication: </i>2025 Oct 22.
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              Text: 2025 Oct 22
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