Evaluation of Polygenic Risk Scores for a Possible Genetic Basis of the Inverse Association Between Cancer and Cognitive Decline.

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Title: Evaluation of Polygenic Risk Scores for a Possible Genetic Basis of the Inverse Association Between Cancer and Cognitive Decline.
Authors: Graff RE; Department of Epidemiology and Biostatistics., Chen DM; Department of Epidemiology and Biostatistics., Swinnerton KN; Department of Epidemiology and Biostatistics.; VA Boston Health Care System., Ackley SF; Department of Epidemiology and Biostatistics.; Department of Epidemiology, Boston University, Boston, MA., Ospina-Romero M; Department of Epidemiology and Biostatistics.; Department of Pathology and Laboratory Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI., Zimmerman SC; Department of Epidemiology and Biostatistics., Wang J; Department of Epidemiology and Biostatistics.; Department of Epidemiology, Boston University, Boston, MA., Buto P; Department of Epidemiology and Biostatistics.; Department of Epidemiology, Boston University, Boston, MA., Nierenberg JL; Department of Epidemiology and Biostatistics., Elahi FM; Department of Neurology, Memory and Aging Center, University of California, San Francisco, San Francisco.; Departments of Neurology and Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY., Lu KP; Department of Biochemistry and Robarts Research Institute, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada., Witte JS; Department of Epidemiology and Biostatistics.; Department of Epidemiology and Population Health, Stanford University, Stanford, CA., Glymour MM; Department of Epidemiology and Biostatistics.; Department of Epidemiology, Boston University, Boston, MA.
Source: Alzheimer disease and associated disorders [Alzheimer Dis Assoc Disord] 2025 Oct-Dec 01; Vol. 39 (4), pp. 235-243. Date of Electronic Publication: 2025 Oct 23.
Publication Type: Journal Article; Evaluation Study
Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 8704771 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-4156 (Electronic) Linking ISSN: 08930341 NLM ISO Abbreviation: Alzheimer Dis Assoc Disord Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Evaluation of Polygenic Risk Scores for a Possible Genetic Basis of the Inverse Association Between Cancer and Cognitive Decline.
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  Data: <searchLink fieldCode="AU" term="%22Graff+RE%22">Graff RE</searchLink>; Department of Epidemiology and Biostatistics.<br /><searchLink fieldCode="AU" term="%22Chen+DM%22">Chen DM</searchLink>; Department of Epidemiology and Biostatistics.<br /><searchLink fieldCode="AU" term="%22Swinnerton+KN%22">Swinnerton KN</searchLink>; Department of Epidemiology and Biostatistics.; VA Boston Health Care System.<br /><searchLink fieldCode="AU" term="%22Ackley+SF%22">Ackley SF</searchLink>; Department of Epidemiology and Biostatistics.; Department of Epidemiology, Boston University, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Ospina-Romero+M%22">Ospina-Romero M</searchLink>; Department of Epidemiology and Biostatistics.; Department of Pathology and Laboratory Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI.<br /><searchLink fieldCode="AU" term="%22Zimmerman+SC%22">Zimmerman SC</searchLink>; Department of Epidemiology and Biostatistics.<br /><searchLink fieldCode="AU" term="%22Wang+J%22">Wang J</searchLink>; Department of Epidemiology and Biostatistics.; Department of Epidemiology, Boston University, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Buto+P%22">Buto P</searchLink>; Department of Epidemiology and Biostatistics.; Department of Epidemiology, Boston University, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Nierenberg+JL%22">Nierenberg JL</searchLink>; Department of Epidemiology and Biostatistics.<br /><searchLink fieldCode="AU" term="%22Elahi+FM%22">Elahi FM</searchLink>; Department of Neurology, Memory and Aging Center, University of California, San Francisco, San Francisco.; Departments of Neurology and Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY.<br /><searchLink fieldCode="AU" term="%22Lu+KP%22">Lu KP</searchLink>; Department of Biochemistry and Robarts Research Institute, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Witte+JS%22">Witte JS</searchLink>; Department of Epidemiology and Biostatistics.; Department of Epidemiology and Population Health, Stanford University, Stanford, CA.<br /><searchLink fieldCode="AU" term="%22Glymour+MM%22">Glymour MM</searchLink>; Department of Epidemiology and Biostatistics.; Department of Epidemiology, Boston University, Boston, MA.
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  Data: <searchLink fieldCode="JN" term="%228704771%22">Alzheimer disease and associated disorders</searchLink> [Alzheimer Dis Assoc Disord] 2025 Oct-Dec 01; Vol. 39 (4), pp. 235-243. <i>Date of Electronic Publication: </i>2025 Oct 23.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Lippincott+Williams+%26+Wilkins%22">Lippincott Williams & Wilkins </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>8704771 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1546-4156 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2208930341%22">08930341 </searchLink><i>NLM ISO Abbreviation: </i>Alzheimer Dis Assoc Disord <i>Subsets: </i>MEDLINE
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        Value: 10.1097/WAD.0000000000000696
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              Text: 2025 Oct-Dec 01
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