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Inclusion of Older Adults in Early-Phase Cancer Clinical Trials: Safety, Efficacy and a Way Forward.

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Title: Inclusion of Older Adults in Early-Phase Cancer Clinical Trials: Safety, Efficacy and a Way Forward.
Authors: Nguyen J; Department of Medical Oncology, Liverpool Hospital, Liverpool, NSW, Australia., Battisti NML; Royal Marsden Hospital, London, UK., Ní Chróinín D; Department of Geriatric Medicine, Liverpool Hospital, Liverpool, NSW, Australia.; South Western Sydney Clinical School, UNSW Sydney, Sydney, NSW, Australia., Hong M; Department of Medical Oncology, Liverpool Hospital, Liverpool, NSW, Australia., Nindra U; Department of Medical Oncology, Liverpool Hospital, Liverpool, NSW, Australia., Hong JH; Department of Medical Oncology, Liverpool Hospital, Liverpool, NSW, Australia., Zwieky W; Department of Medical Oncology, Liverpool Hospital, Liverpool, NSW, Australia., Wilkinson K; Department of Medical Oncology, Liverpool Hospital, Liverpool, NSW, Australia., Yoon R; Department of Medical Oncology, Liverpool Hospital, Liverpool, NSW, Australia., Cooper A; Department of Medical Oncology, Liverpool Hospital, Liverpool, NSW, Australia.; School of Medicine, Western Sydney University, Sydney, NSW, Australia., Roohullah A; Department of Medical Oncology, Liverpool Hospital, Liverpool, NSW, Australia., Ng W; Department of Medical Oncology, Liverpool Hospital, Liverpool, NSW, Australia., Chua W; Department of Medical Oncology, Liverpool Hospital, Liverpool, NSW, Australia.; School of Medicine, Western Sydney University, Sydney, NSW, Australia., Pal A; Department of Medical Oncology, Liverpool Hospital, Liverpool, NSW, Australia. Abhijit.Pal@health.nsw.gov.au.
Source: Drugs & aging [Drugs Aging] 2025 Dec; Vol. 42 (12), pp. 1143-1158. Date of Electronic Publication: 2025 Oct 23.
Publication Type: Journal Article; Review
Journal Info: Publisher: Adis, Springer International Country of Publication: New Zealand NLM ID: 9102074 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1179-1969 (Electronic) Linking ISSN: 1170229X NLM ISO Abbreviation: Drugs Aging Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Inclusion of Older Adults in Early-Phase Cancer Clinical Trials: Safety, Efficacy and a Way Forward.
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  Data: <searchLink fieldCode="AU" term="%22Nguyen+J%22">Nguyen J</searchLink>; Department of Medical Oncology, Liverpool Hospital, Liverpool, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Battisti+NML%22">Battisti NML</searchLink>; Royal Marsden Hospital, London, UK.<br /><searchLink fieldCode="AU" term="%22Ní+Chróinín+D%22">Ní Chróinín D</searchLink>; Department of Geriatric Medicine, Liverpool Hospital, Liverpool, NSW, Australia.; South Western Sydney Clinical School, UNSW Sydney, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Hong+M%22">Hong M</searchLink>; Department of Medical Oncology, Liverpool Hospital, Liverpool, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Nindra+U%22">Nindra U</searchLink>; Department of Medical Oncology, Liverpool Hospital, Liverpool, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Hong+JH%22">Hong JH</searchLink>; Department of Medical Oncology, Liverpool Hospital, Liverpool, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Zwieky+W%22">Zwieky W</searchLink>; Department of Medical Oncology, Liverpool Hospital, Liverpool, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Wilkinson+K%22">Wilkinson K</searchLink>; Department of Medical Oncology, Liverpool Hospital, Liverpool, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Yoon+R%22">Yoon R</searchLink>; Department of Medical Oncology, Liverpool Hospital, Liverpool, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Cooper+A%22">Cooper A</searchLink>; Department of Medical Oncology, Liverpool Hospital, Liverpool, NSW, Australia.; School of Medicine, Western Sydney University, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Roohullah+A%22">Roohullah A</searchLink>; Department of Medical Oncology, Liverpool Hospital, Liverpool, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Ng+W%22">Ng W</searchLink>; Department of Medical Oncology, Liverpool Hospital, Liverpool, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Chua+W%22">Chua W</searchLink>; Department of Medical Oncology, Liverpool Hospital, Liverpool, NSW, Australia.; School of Medicine, Western Sydney University, Sydney, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Pal+A%22">Pal A</searchLink>; Department of Medical Oncology, Liverpool Hospital, Liverpool, NSW, Australia. Abhijit.Pal@health.nsw.gov.au.
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  Data: <searchLink fieldCode="JN" term="%229102074%22">Drugs & aging</searchLink> [Drugs Aging] 2025 Dec; Vol. 42 (12), pp. 1143-1158. <i>Date of Electronic Publication: </i>2025 Oct 23.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Adis%2C+Springer+International%22">Adis, Springer International </searchLink><i>Country of Publication: </i>New Zealand <i>NLM ID: </i>9102074 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1179-1969 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%221170229X%22">1170229X </searchLink><i>NLM ISO Abbreviation: </i>Drugs Aging <i>Subsets: </i>MEDLINE
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              Text: 2025 Dec
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