View in EDS

Remission of TP53-Mutant AML After Transplantation With Trem-Cel, a CRISPR/Cas9 Gene-Edited Allograft Lacking CD33, Followed by a Donor-Derived Anti-CD33 Chimeric Antigen Receptor T (VCAR33).

Saved in:
Bibliographic Details
Title: Remission of TP53-Mutant AML After Transplantation With Trem-Cel, a CRISPR/Cas9 Gene-Edited Allograft Lacking CD33, Followed by a Donor-Derived Anti-CD33 Chimeric Antigen Receptor T (VCAR33).
Authors: Koehne G; Miami Cancer Institute, Baptist Health South Florida, Miami, FL., Mushtaq MU; Division of Hematologic Malignancies & Cellular Therapeutics, University of Kansas Cancer Center, Westwood, KS., Muffly LS; Division of Blood and Marrow Transplantation & Cellular Therapy, Stanford University, Palo Alto, CA., Menes M; Miami Cancer Institute, Baptist Health South Florida, Miami, FL., Azzi J; The Tisch Cancer Institute and Division of Hematology/Medical Oncology, Icahn School of Medicine at Mount Sinai, New York, NY., Bernard L; Programme de greffe & thérapie cellulaire, Hôpital Maisonneuve-Rosemont, Montreal, Quebec, Canada., Cooper B; Adult Hematologic Malignancies & Stem Cell Transplant, Seidman Cancer Center, University Hospitals Cleveland Medical Center, Cleveland, OH., Kennedy V; Division of Blood and Marrow Transplantation & Cellular Therapy, Stanford University, Palo Alto, CA., Koura D; Division of Hematology-Oncology and Bone Marrow Transplantation, Department of Medicine, University of California San Diego Moores Cancer Center, San Diego, CA., Maakaron J; Division of Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis, MN., Magenau J; Department of Internal Medicine, Rogel Cancer Center, University of Michigan, Ann Arbor, MI., McClune B; Department of Internal Medicine, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT., Patel SS; Department of Internal Medicine, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT., Rimando JC; Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory University, Atlanta, GA., Shah NN; Pediatric Oncology Branch, National Cancer Institute, Bethesda, MD., Suh HC; John Theurer Cancer Center, Hackensack University Medical Center, Hackensack Meridian School of Medicine, Hackensack, NJ., Tamari R; Department of Medicine, Bone Marrow Transplant Service, Memorial Sloan Kettering Cancer Center, New York, NY., Thosar S; Vor Bio, Cambridge, MA., Canesin G; Vor Bio, Cambridge, MA., Hyzy SL; Vor Bio, Cambridge, MA., Lee-Sundlov MM; Vor Bio, Cambridge, MA., Stanizzi DA; Vor Bio, Cambridge, MA., Hummel D; Vor Bio, Cambridge, MA., Lin MI; Vor Bio, Cambridge, MA., Raffel GD; Vor Bio, Cambridge, MA., Whangbo JS; Vor Bio, Cambridge, MA., DiPersio JF; Department of Medicine, Division of Oncology, Washington University School of Medicine, St Louis, MO.
Source: JCO precision oncology [JCO Precis Oncol] 2025 Oct; Vol. 9, pp. e2500556. Date of Electronic Publication: 2025 Oct 23.
Publication Type: Journal Article
Journal Info: Publisher: American Society of Clinical Oncology Country of Publication: United States NLM ID: 101705370 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2473-4284 (Electronic) Linking ISSN: 24734284 NLM ISO Abbreviation: JCO Precis Oncol Subsets: MEDLINE; In Process
Database: MEDLINE Ultimate
FullText Text:
  Availability: 0
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 41129765
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Remission of TP53-Mutant AML After Transplantation With Trem-Cel, a CRISPR/Cas9 Gene-Edited Allograft Lacking CD33, Followed by a Donor-Derived Anti-CD33 Chimeric Antigen Receptor T (VCAR33).
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Koehne+G%22">Koehne G</searchLink>; Miami Cancer Institute, Baptist Health South Florida, Miami, FL.<br /><searchLink fieldCode="AU" term="%22Mushtaq+MU%22">Mushtaq MU</searchLink>; Division of Hematologic Malignancies & Cellular Therapeutics, University of Kansas Cancer Center, Westwood, KS.<br /><searchLink fieldCode="AU" term="%22Muffly+LS%22">Muffly LS</searchLink>; Division of Blood and Marrow Transplantation & Cellular Therapy, Stanford University, Palo Alto, CA.<br /><searchLink fieldCode="AU" term="%22Menes+M%22">Menes M</searchLink>; Miami Cancer Institute, Baptist Health South Florida, Miami, FL.<br /><searchLink fieldCode="AU" term="%22Azzi+J%22">Azzi J</searchLink>; The Tisch Cancer Institute and Division of Hematology/Medical Oncology, Icahn School of Medicine at Mount Sinai, New York, NY.<br /><searchLink fieldCode="AU" term="%22Bernard+L%22">Bernard L</searchLink>; Programme de greffe & thérapie cellulaire, Hôpital Maisonneuve-Rosemont, Montreal, Quebec, Canada.<br /><searchLink fieldCode="AU" term="%22Cooper+B%22">Cooper B</searchLink>; Adult Hematologic Malignancies & Stem Cell Transplant, Seidman Cancer Center, University Hospitals Cleveland Medical Center, Cleveland, OH.<br /><searchLink fieldCode="AU" term="%22Kennedy+V%22">Kennedy V</searchLink>; Division of Blood and Marrow Transplantation & Cellular Therapy, Stanford University, Palo Alto, CA.<br /><searchLink fieldCode="AU" term="%22Koura+D%22">Koura D</searchLink>; Division of Hematology-Oncology and Bone Marrow Transplantation, Department of Medicine, University of California San Diego Moores Cancer Center, San Diego, CA.<br /><searchLink fieldCode="AU" term="%22Maakaron+J%22">Maakaron J</searchLink>; Division of Hematology, Oncology and Transplantation, University of Minnesota, Minneapolis, MN.<br /><searchLink fieldCode="AU" term="%22Magenau+J%22">Magenau J</searchLink>; Department of Internal Medicine, Rogel Cancer Center, University of Michigan, Ann Arbor, MI.<br /><searchLink fieldCode="AU" term="%22McClune+B%22">McClune B</searchLink>; Department of Internal Medicine, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT.<br /><searchLink fieldCode="AU" term="%22Patel+SS%22">Patel SS</searchLink>; Department of Internal Medicine, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT.<br /><searchLink fieldCode="AU" term="%22Rimando+JC%22">Rimando JC</searchLink>; Department of Hematology and Medical Oncology, Winship Cancer Institute of Emory University, Atlanta, GA.<br /><searchLink fieldCode="AU" term="%22Shah+NN%22">Shah NN</searchLink>; Pediatric Oncology Branch, National Cancer Institute, Bethesda, MD.<br /><searchLink fieldCode="AU" term="%22Suh+HC%22">Suh HC</searchLink>; John Theurer Cancer Center, Hackensack University Medical Center, Hackensack Meridian School of Medicine, Hackensack, NJ.<br /><searchLink fieldCode="AU" term="%22Tamari+R%22">Tamari R</searchLink>; Department of Medicine, Bone Marrow Transplant Service, Memorial Sloan Kettering Cancer Center, New York, NY.<br /><searchLink fieldCode="AU" term="%22Thosar+S%22">Thosar S</searchLink>; Vor Bio, Cambridge, MA.<br /><searchLink fieldCode="AU" term="%22Canesin+G%22">Canesin G</searchLink>; Vor Bio, Cambridge, MA.<br /><searchLink fieldCode="AU" term="%22Hyzy+SL%22">Hyzy SL</searchLink>; Vor Bio, Cambridge, MA.<br /><searchLink fieldCode="AU" term="%22Lee-Sundlov+MM%22">Lee-Sundlov MM</searchLink>; Vor Bio, Cambridge, MA.<br /><searchLink fieldCode="AU" term="%22Stanizzi+DA%22">Stanizzi DA</searchLink>; Vor Bio, Cambridge, MA.<br /><searchLink fieldCode="AU" term="%22Hummel+D%22">Hummel D</searchLink>; Vor Bio, Cambridge, MA.<br /><searchLink fieldCode="AU" term="%22Lin+MI%22">Lin MI</searchLink>; Vor Bio, Cambridge, MA.<br /><searchLink fieldCode="AU" term="%22Raffel+GD%22">Raffel GD</searchLink>; Vor Bio, Cambridge, MA.<br /><searchLink fieldCode="AU" term="%22Whangbo+JS%22">Whangbo JS</searchLink>; Vor Bio, Cambridge, MA.<br /><searchLink fieldCode="AU" term="%22DiPersio+JF%22">DiPersio JF</searchLink>; Department of Medicine, Division of Oncology, Washington University School of Medicine, St Louis, MO.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101705370%22">JCO precision oncology</searchLink> [JCO Precis Oncol] 2025 Oct; Vol. 9, pp. e2500556. <i>Date of Electronic Publication: </i>2025 Oct 23.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Society+of+Clinical+Oncology%22">American Society of Clinical Oncology </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101705370 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2473-4284 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2224734284%22">24734284 </searchLink><i>NLM ISO Abbreviation: </i>JCO Precis Oncol <i>Subsets: </i>MEDLINE; In Process
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41129765
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1200/PO-25-00556
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: e2500556
    Titles:
      – TitleFull: Remission of TP53-Mutant AML After Transplantation With Trem-Cel, a CRISPR/Cas9 Gene-Edited Allograft Lacking CD33, Followed by a Donor-Derived Anti-CD33 Chimeric Antigen Receptor T (VCAR33).
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Koehne G
      – PersonEntity:
          Name:
            NameFull: Mushtaq MU
      – PersonEntity:
          Name:
            NameFull: Muffly LS
      – PersonEntity:
          Name:
            NameFull: Menes M
      – PersonEntity:
          Name:
            NameFull: Azzi J
      – PersonEntity:
          Name:
            NameFull: Bernard L
      – PersonEntity:
          Name:
            NameFull: Cooper B
      – PersonEntity:
          Name:
            NameFull: Kennedy V
      – PersonEntity:
          Name:
            NameFull: Koura D
      – PersonEntity:
          Name:
            NameFull: Maakaron J
      – PersonEntity:
          Name:
            NameFull: Magenau J
      – PersonEntity:
          Name:
            NameFull: McClune B
      – PersonEntity:
          Name:
            NameFull: Patel SS
      – PersonEntity:
          Name:
            NameFull: Rimando JC
      – PersonEntity:
          Name:
            NameFull: Shah NN
      – PersonEntity:
          Name:
            NameFull: Suh HC
      – PersonEntity:
          Name:
            NameFull: Tamari R
      – PersonEntity:
          Name:
            NameFull: Thosar S
      – PersonEntity:
          Name:
            NameFull: Canesin G
      – PersonEntity:
          Name:
            NameFull: Hyzy SL
      – PersonEntity:
          Name:
            NameFull: Lee-Sundlov MM
      – PersonEntity:
          Name:
            NameFull: Stanizzi DA
      – PersonEntity:
          Name:
            NameFull: Hummel D
      – PersonEntity:
          Name:
            NameFull: Lin MI
      – PersonEntity:
          Name:
            NameFull: Raffel GD
      – PersonEntity:
          Name:
            NameFull: Whangbo JS
      – PersonEntity:
          Name:
            NameFull: DiPersio JF
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 10
              Text: 2025 Oct
              Type: published
              Y: 2025
          Identifiers:
            – Type: issn-electronic
              Value: 2473-4284
          Numbering:
            – Type: volume
              Value: 9
          Titles:
            – TitleFull: JCO precision oncology
              Type: main
ResultId 1