A Multitrait Polygenic Risk Score for Open-Angle Glaucoma Stratifies Risk of Pigmentary Glaucoma in Pigment Dispersion Syndrome.
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| Title: | A Multitrait Polygenic Risk Score for Open-Angle Glaucoma Stratifies Risk of Pigmentary Glaucoma in Pigment Dispersion Syndrome. |
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| Authors: | Kolovos A; Flinders Eye and Vision, College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia; Department of Ophthalmology, Flinders Medical Centre, Adelaide, South Australia, Australia. Electronic address: antonia.kolovos@flinders.edu.au., Qassim A; Flinders Eye and Vision, College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia; Department of Ophthalmology, Flinders Medical Centre, Adelaide, South Australia, Australia., Marshall HN; Flinders Eye and Vision, College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia., Nguyen TT; Flinders Eye and Vision, College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia; Department of Ophthalmology, Flinders Medical Centre, Adelaide, South Australia, Australia., Schmidt J; Flinders Eye and Vision, College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia., Hassall MM; Flinders Eye and Vision, College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia; Department of Ophthalmology, Flinders Medical Centre, Adelaide, South Australia, Australia., Tang V; Flinders Eye and Vision, College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia., Maxwell G; Flinders Eye and Vision, College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia., Landers J; Flinders Eye and Vision, College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia; Department of Ophthalmology, Flinders Medical Centre, Adelaide, South Australia, Australia., Mills R; Flinders Eye and Vision, College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia; Department of Ophthalmology, Flinders Medical Centre, Adelaide, South Australia, Australia., Lake S; Flinders Eye and Vision, College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia; Department of Ophthalmology, Flinders Medical Centre, Adelaide, South Australia, Australia., Graham SL; Faculty of Medicine, Health and Human Sciences, Ophthalmology and Vision Science, Macquarie University, Sydney, New South Wales, Australia., Schulz A; Faculty of Medicine, Health and Human Sciences, Ophthalmology and Vision Science, Macquarie University, Sydney, New South Wales, Australia., Galanopoulos A; Ophthalmic Research Laboratories, University of Adelaide, Adelaide Health and Medical Sciences Building, Adelaide, South Australia, Australia., Casson RJ; Ophthalmic Research Laboratories, University of Adelaide, Adelaide Health and Medical Sciences Building, Adelaide, South Australia, Australia., Goldberg I; Discipline of Ophthalmology, University of Sydney, Sydney Eye Hospital, Sydney, New South Wales, Australia., Coote M; Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, Melbourne, Victoria, Australia., Best S; Eye Department, Greenlane Clinical Centre, Auckland District Health Board, Auckland, New Zealand., Lusthaus J; Discipline of Ophthalmology, University of Sydney, Sydney Eye Hospital, Sydney, New South Wales, Australia., Healey PR; Department of Ophthalmology, Centre for Vision Research, Westmead Institute for Medical Research, University of Sydney, Sydney, New South Wales, Australia., Burnett L; Genomics and Inherited Diseases, Garvan Institute of Medical Research, Sydney, New South Wales, Australia; Faculty of Medicine and Health, University of New South Wales, Sydney, New South Wales, Australia., Töteberg-Harms M; Department of Ophthalmology and Visual Sciences, Carver College of Medicine, University of Iowa, Iowa City, Iowa; Institute for Vision Research, University of Iowa, Iowa City, Iowa., Boese EA; Department of Ophthalmology and Visual Sciences, Carver College of Medicine, University of Iowa, Iowa City, Iowa; Institute for Vision Research, University of Iowa, Iowa City, Iowa., Pouw AE; Department of Ophthalmology and Visual Sciences, Carver College of Medicine, University of Iowa, Iowa City, Iowa; Institute for Vision Research, University of Iowa, Iowa City, Iowa., Gharahkhani P; Statistical Genetics Laboratory, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia; School of Biomedical Sciences, Faculty of Medicine, The University of Queensland, Brisbane, Queensland, Australia., Scheetz T; Department of Ophthalmology and Visual Sciences, Carver College of Medicine, University of Iowa, Iowa City, Iowa; Institute for Vision Research, University of Iowa, Iowa City, Iowa., Hewitt AW; Centre for Ophthalmology and Visual Science, University of Western Australia, Lions Eye Institute, Perth, Western Australia, Australia; Department of Ophthalmology, Menzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, Australia., MacGregor S; Statistical Genetics Laboratory, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia; School of Biomedical Sciences, Faculty of Medicine, The University of Queensland, Brisbane, Queensland, Australia., Siggs OM; Genomics and Inherited Diseases, Garvan Institute of Medical Research, Sydney, New South Wales, Australia; Faculty of Medicine and Health, University of New South Wales, Sydney, New South Wales, Australia., Souzeau E; Flinders Eye and Vision, College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia., Fingert JH; Department of Ophthalmology and Visual Sciences, Carver College of Medicine, University of Iowa, Iowa City, Iowa; Institute for Vision Research, University of Iowa, Iowa City, Iowa., Craig JE; Flinders Eye and Vision, College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia; Department of Ophthalmology, Flinders Medical Centre, Adelaide, South Australia, Australia. |
| Source: | Ophthalmology. Glaucoma [Ophthalmol Glaucoma] 2026 Mar-Apr; Vol. 9 (2), pp. 193-201. Date of Electronic Publication: 2025 Oct 21. |
| Publication Type: | Journal Article; Multicenter Study; Research Support, N.I.H., Extramural |
| Journal Info: | Publisher: Elsevier Inc Country of Publication: United States NLM ID: 101730510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2589-4196 (Electronic) Linking ISSN: 25894196 NLM ISO Abbreviation: Ophthalmol Glaucoma Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41130539 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: A Multitrait Polygenic Risk Score for Open-Angle Glaucoma Stratifies Risk of Pigmentary Glaucoma in Pigment Dispersion Syndrome. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Kolovos+A%22">Kolovos A</searchLink>; Flinders Eye and Vision, College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia; Department of Ophthalmology, Flinders Medical Centre, Adelaide, South Australia, Australia. Electronic address: antonia.kolovos@flinders.edu.au.<br /><searchLink fieldCode="AU" term="%22Qassim+A%22">Qassim A</searchLink>; Flinders Eye and Vision, College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia; Department of Ophthalmology, Flinders Medical Centre, Adelaide, South Australia, Australia.<br /><searchLink fieldCode="AU" term="%22Marshall+HN%22">Marshall HN</searchLink>; Flinders Eye and Vision, College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia.<br /><searchLink fieldCode="AU" term="%22Nguyen+TT%22">Nguyen TT</searchLink>; Flinders Eye and Vision, College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia; Department of Ophthalmology, Flinders Medical Centre, Adelaide, South Australia, Australia.<br /><searchLink fieldCode="AU" term="%22Schmidt+J%22">Schmidt J</searchLink>; Flinders Eye and Vision, College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia.<br /><searchLink fieldCode="AU" term="%22Hassall+MM%22">Hassall MM</searchLink>; Flinders Eye and Vision, College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia; Department of Ophthalmology, Flinders Medical Centre, Adelaide, South Australia, Australia.<br /><searchLink fieldCode="AU" term="%22Tang+V%22">Tang V</searchLink>; Flinders Eye and Vision, College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia.<br /><searchLink fieldCode="AU" term="%22Maxwell+G%22">Maxwell G</searchLink>; Flinders Eye and Vision, College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia.<br /><searchLink fieldCode="AU" term="%22Landers+J%22">Landers J</searchLink>; Flinders Eye and Vision, College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia; Department of Ophthalmology, Flinders Medical Centre, Adelaide, South Australia, Australia.<br /><searchLink fieldCode="AU" term="%22Mills+R%22">Mills R</searchLink>; Flinders Eye and Vision, College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia; Department of Ophthalmology, Flinders Medical Centre, Adelaide, South Australia, Australia.<br /><searchLink fieldCode="AU" term="%22Lake+S%22">Lake S</searchLink>; Flinders Eye and Vision, College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia; Department of Ophthalmology, Flinders Medical Centre, Adelaide, South Australia, Australia.<br /><searchLink fieldCode="AU" term="%22Graham+SL%22">Graham SL</searchLink>; Faculty of Medicine, Health and Human Sciences, Ophthalmology and Vision Science, Macquarie University, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Schulz+A%22">Schulz A</searchLink>; Faculty of Medicine, Health and Human Sciences, Ophthalmology and Vision Science, Macquarie University, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Galanopoulos+A%22">Galanopoulos A</searchLink>; Ophthalmic Research Laboratories, University of Adelaide, Adelaide Health and Medical Sciences Building, Adelaide, South Australia, Australia.<br /><searchLink fieldCode="AU" term="%22Casson+RJ%22">Casson RJ</searchLink>; Ophthalmic Research Laboratories, University of Adelaide, Adelaide Health and Medical Sciences Building, Adelaide, South Australia, Australia.<br /><searchLink fieldCode="AU" term="%22Goldberg+I%22">Goldberg I</searchLink>; Discipline of Ophthalmology, University of Sydney, Sydney Eye Hospital, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Coote+M%22">Coote M</searchLink>; Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Best+S%22">Best S</searchLink>; Eye Department, Greenlane Clinical Centre, Auckland District Health Board, Auckland, New Zealand.<br /><searchLink fieldCode="AU" term="%22Lusthaus+J%22">Lusthaus J</searchLink>; Discipline of Ophthalmology, University of Sydney, Sydney Eye Hospital, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Healey+PR%22">Healey PR</searchLink>; Department of Ophthalmology, Centre for Vision Research, Westmead Institute for Medical Research, University of Sydney, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Burnett+L%22">Burnett L</searchLink>; Genomics and Inherited Diseases, Garvan Institute of Medical Research, Sydney, New South Wales, Australia; Faculty of Medicine and Health, University of New South Wales, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Töteberg-Harms+M%22">Töteberg-Harms M</searchLink>; Department of Ophthalmology and Visual Sciences, Carver College of Medicine, University of Iowa, Iowa City, Iowa; Institute for Vision Research, University of Iowa, Iowa City, Iowa.<br /><searchLink fieldCode="AU" term="%22Boese+EA%22">Boese EA</searchLink>; Department of Ophthalmology and Visual Sciences, Carver College of Medicine, University of Iowa, Iowa City, Iowa; Institute for Vision Research, University of Iowa, Iowa City, Iowa.<br /><searchLink fieldCode="AU" term="%22Pouw+AE%22">Pouw AE</searchLink>; Department of Ophthalmology and Visual Sciences, Carver College of Medicine, University of Iowa, Iowa City, Iowa; Institute for Vision Research, University of Iowa, Iowa City, Iowa.<br /><searchLink fieldCode="AU" term="%22Gharahkhani+P%22">Gharahkhani P</searchLink>; Statistical Genetics Laboratory, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia; School of Biomedical Sciences, Faculty of Medicine, The University of Queensland, Brisbane, Queensland, Australia.<br /><searchLink fieldCode="AU" term="%22Scheetz+T%22">Scheetz T</searchLink>; Department of Ophthalmology and Visual Sciences, Carver College of Medicine, University of Iowa, Iowa City, Iowa; Institute for Vision Research, University of Iowa, Iowa City, Iowa.<br /><searchLink fieldCode="AU" term="%22Hewitt+AW%22">Hewitt AW</searchLink>; Centre for Ophthalmology and Visual Science, University of Western Australia, Lions Eye Institute, Perth, Western Australia, Australia; Department of Ophthalmology, Menzies Institute for Medical Research, University of Tasmania, Hobart, Tasmania, Australia.<br /><searchLink fieldCode="AU" term="%22MacGregor+S%22">MacGregor S</searchLink>; Statistical Genetics Laboratory, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia; School of Biomedical Sciences, Faculty of Medicine, The University of Queensland, Brisbane, Queensland, Australia.<br /><searchLink fieldCode="AU" term="%22Siggs+OM%22">Siggs OM</searchLink>; Genomics and Inherited Diseases, Garvan Institute of Medical Research, Sydney, New South Wales, Australia; Faculty of Medicine and Health, University of New South Wales, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Souzeau+E%22">Souzeau E</searchLink>; Flinders Eye and Vision, College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia.<br /><searchLink fieldCode="AU" term="%22Fingert+JH%22">Fingert JH</searchLink>; Department of Ophthalmology and Visual Sciences, Carver College of Medicine, University of Iowa, Iowa City, Iowa; Institute for Vision Research, University of Iowa, Iowa City, Iowa.<br /><searchLink fieldCode="AU" term="%22Craig+JE%22">Craig JE</searchLink>; Flinders Eye and Vision, College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia; Department of Ophthalmology, Flinders Medical Centre, Adelaide, South Australia, Australia. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101730510%22">Ophthalmology. Glaucoma</searchLink> [Ophthalmol Glaucoma] 2026 Mar-Apr; Vol. 9 (2), pp. 193-201. <i>Date of Electronic Publication: </i>2025 Oct 21. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Multicenter Study; Research Support, N.I.H., Extramural – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Inc%22">Elsevier Inc </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101730510 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2589-4196 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2225894196%22">25894196 </searchLink><i>NLM ISO Abbreviation: </i>Ophthalmol Glaucoma <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41130539 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.ogla.2025.10.005 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 193 Titles: – TitleFull: A Multitrait Polygenic Risk Score for Open-Angle Glaucoma Stratifies Risk of Pigmentary Glaucoma in Pigment Dispersion Syndrome. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Kolovos A – PersonEntity: Name: NameFull: Qassim A – PersonEntity: Name: NameFull: Marshall HN – PersonEntity: Name: NameFull: Nguyen TT – PersonEntity: Name: NameFull: Schmidt J – PersonEntity: Name: NameFull: Hassall MM – PersonEntity: Name: NameFull: Tang V – PersonEntity: Name: NameFull: Maxwell G – PersonEntity: Name: NameFull: Landers J – PersonEntity: Name: NameFull: Mills R – PersonEntity: Name: NameFull: Lake S – PersonEntity: Name: NameFull: Graham SL – PersonEntity: Name: NameFull: Schulz A – PersonEntity: Name: NameFull: Galanopoulos A – PersonEntity: Name: NameFull: Casson RJ – PersonEntity: Name: NameFull: Goldberg I – PersonEntity: Name: NameFull: Coote M – PersonEntity: Name: NameFull: Best S – PersonEntity: Name: NameFull: Lusthaus J – PersonEntity: Name: NameFull: Healey PR – PersonEntity: Name: NameFull: Burnett L – PersonEntity: Name: NameFull: Töteberg-Harms M – PersonEntity: Name: NameFull: Boese EA – PersonEntity: Name: NameFull: Pouw AE – PersonEntity: Name: NameFull: Gharahkhani P – PersonEntity: Name: NameFull: Scheetz T – PersonEntity: Name: NameFull: Hewitt AW – PersonEntity: Name: NameFull: MacGregor S – PersonEntity: Name: NameFull: Siggs OM – PersonEntity: Name: NameFull: Souzeau E – PersonEntity: Name: NameFull: Fingert JH – PersonEntity: Name: NameFull: Craig JE IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 03 Text: 2026 Mar-Apr Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 2589-4196 Numbering: – Type: volume Value: 9 – Type: issue Value: 2 Titles: – TitleFull: Ophthalmology. Glaucoma Type: main |
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