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FAP+ fibroblasts orchestrate tumor microenvironment remodeling in renal cell carcinoma with tumor thrombus.

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Title: FAP+ fibroblasts orchestrate tumor microenvironment remodeling in renal cell carcinoma with tumor thrombus.
Authors: Ma J; Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, China.; State Key Laboratory of Medical Proteomics, National Center for Protein Sciences (Beijing), Research Unit of Proteomics Driven Cancer Precision Medicine (Chinese Academy of Medical Sciences), Beijing, China., Huang Y; Senior Department of Urology, Chinese PLA General Hospital, Beijing, China., Chen J; State Key Laboratory of Medical Proteomics, National Center for Protein Sciences (Beijing), Research Unit of Proteomics Driven Cancer Precision Medicine (Chinese Academy of Medical Sciences), Beijing, China.; Cancer Center, Renmin Hospital of Wuhan University, Wuhan, China., Li Y; State Key Laboratory of Medical Proteomics, National Center for Protein Sciences (Beijing), Research Unit of Proteomics Driven Cancer Precision Medicine (Chinese Academy of Medical Sciences), Beijing, China., Yao R; State Key Laboratory of Medical Proteomics, National Center for Protein Sciences (Beijing), Research Unit of Proteomics Driven Cancer Precision Medicine (Chinese Academy of Medical Sciences), Beijing, China.; School of Medicine, Tsinghua University, Beijing, China., Li X; Senior Department of Urology, Chinese PLA General Hospital, Beijing, China., Liang Q; Senior Department of Urology, Chinese PLA General Hospital, Beijing, China., Chen X; Senior Department of Urology, Chinese PLA General Hospital, Beijing, China., Peng C; Senior Department of Urology, Chinese PLA General Hospital, Beijing, China., Liu K; Senior Department of Urology, Chinese PLA General Hospital, Beijing, China., Zhai Y; State Key Laboratory of Medical Proteomics, National Center for Protein Sciences (Beijing), Research Unit of Proteomics Driven Cancer Precision Medicine (Chinese Academy of Medical Sciences), Beijing, China., Zhang X; Senior Department of Urology, Chinese PLA General Hospital, Beijing, China., Ma X; Senior Department of Urology, Chinese PLA General Hospital, Beijing, China. mxin301@126.com., Wang X; State Key Laboratory of Medical Proteomics, National Center for Protein Sciences (Beijing), Research Unit of Proteomics Driven Cancer Precision Medicine (Chinese Academy of Medical Sciences), Beijing, China. wangxiaowen@ncpsb.org.cn., Huang Q; Senior Department of Urology, Chinese PLA General Hospital, Beijing, China. gdhuangqingbo@163.com., He F; State Key Laboratory of Medical Proteomics, National Center for Protein Sciences (Beijing), Research Unit of Proteomics Driven Cancer Precision Medicine (Chinese Academy of Medical Sciences), Beijing, China. hefc@bmi.ac.cn.; International Academy of Phronesis Medicine (Guangdong), Guangzhou, China. hefc@bmi.ac.cn.
Source: Nature communications [Nat Commun] 2025 Oct 23; Vol. 16 (1), pp. 9387. Date of Electronic Publication: 2025 Oct 23.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: FAP<superscript>+</superscript> fibroblasts orchestrate tumor microenvironment remodeling in renal cell carcinoma with tumor thrombus.
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  Data: <searchLink fieldCode="AU" term="%22Ma+J%22">Ma J</searchLink>; Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, China.; State Key Laboratory of Medical Proteomics, National Center for Protein Sciences (Beijing), Research Unit of Proteomics Driven Cancer Precision Medicine (Chinese Academy of Medical Sciences), Beijing, China.<br /><searchLink fieldCode="AU" term="%22Huang+Y%22">Huang Y</searchLink>; Senior Department of Urology, Chinese PLA General Hospital, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Chen+J%22">Chen J</searchLink>; State Key Laboratory of Medical Proteomics, National Center for Protein Sciences (Beijing), Research Unit of Proteomics Driven Cancer Precision Medicine (Chinese Academy of Medical Sciences), Beijing, China.; Cancer Center, Renmin Hospital of Wuhan University, Wuhan, China.<br /><searchLink fieldCode="AU" term="%22Li+Y%22">Li Y</searchLink>; State Key Laboratory of Medical Proteomics, National Center for Protein Sciences (Beijing), Research Unit of Proteomics Driven Cancer Precision Medicine (Chinese Academy of Medical Sciences), Beijing, China.<br /><searchLink fieldCode="AU" term="%22Yao+R%22">Yao R</searchLink>; State Key Laboratory of Medical Proteomics, National Center for Protein Sciences (Beijing), Research Unit of Proteomics Driven Cancer Precision Medicine (Chinese Academy of Medical Sciences), Beijing, China.; School of Medicine, Tsinghua University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Li+X%22">Li X</searchLink>; Senior Department of Urology, Chinese PLA General Hospital, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Liang+Q%22">Liang Q</searchLink>; Senior Department of Urology, Chinese PLA General Hospital, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Chen+X%22">Chen X</searchLink>; Senior Department of Urology, Chinese PLA General Hospital, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Peng+C%22">Peng C</searchLink>; Senior Department of Urology, Chinese PLA General Hospital, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Liu+K%22">Liu K</searchLink>; Senior Department of Urology, Chinese PLA General Hospital, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Zhai+Y%22">Zhai Y</searchLink>; State Key Laboratory of Medical Proteomics, National Center for Protein Sciences (Beijing), Research Unit of Proteomics Driven Cancer Precision Medicine (Chinese Academy of Medical Sciences), Beijing, China.<br /><searchLink fieldCode="AU" term="%22Zhang+X%22">Zhang X</searchLink>; Senior Department of Urology, Chinese PLA General Hospital, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Ma+X%22">Ma X</searchLink>; Senior Department of Urology, Chinese PLA General Hospital, Beijing, China. mxin301@126.com.<br /><searchLink fieldCode="AU" term="%22Wang+X%22">Wang X</searchLink>; State Key Laboratory of Medical Proteomics, National Center for Protein Sciences (Beijing), Research Unit of Proteomics Driven Cancer Precision Medicine (Chinese Academy of Medical Sciences), Beijing, China. wangxiaowen@ncpsb.org.cn.<br /><searchLink fieldCode="AU" term="%22Huang+Q%22">Huang Q</searchLink>; Senior Department of Urology, Chinese PLA General Hospital, Beijing, China. gdhuangqingbo@163.com.<br /><searchLink fieldCode="AU" term="%22He+F%22">He F</searchLink>; State Key Laboratory of Medical Proteomics, National Center for Protein Sciences (Beijing), Research Unit of Proteomics Driven Cancer Precision Medicine (Chinese Academy of Medical Sciences), Beijing, China. hefc@bmi.ac.cn.; International Academy of Phronesis Medicine (Guangdong), Guangzhou, China. hefc@bmi.ac.cn.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2025 Oct 23; Vol. 16 (1), pp. 9387. <i>Date of Electronic Publication: </i>2025 Oct 23.
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