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High-resolution native electrophoresis in-gel activity assay reveals biological insights of medium-chain fatty acyl-CoA dehydrogenase deficiency.

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Title: High-resolution native electrophoresis in-gel activity assay reveals biological insights of medium-chain fatty acyl-CoA dehydrogenase deficiency.
Authors: Guerrero-Castillo S; University Children's Research@Kinder-UKE, University Medical Center Hamburg-Eppendorf (UKE), 20246, Hamburg, Germany. s.guerrerocastillo@uke.de.; German Center for Child and Adolescent Health (DZKJ), Partner Site Hamburg, University Medical Center Hamburg-Eppendorf (UKE), 20246, Hamburg, Germany. s.guerrerocastillo@uke.de., Grün A; CSSB Centre for Structural Systems Biology, Deutsches Elektronen Synchrotron DESY and Leibniz Institute of Virology (LIV) and University of Lübeck, 22607, Hamburg, Germany., Lewandowski N; University Children's Research@Kinder-UKE, University Medical Center Hamburg-Eppendorf (UKE), 20246, Hamburg, Germany., Gundorova P; University Children's Research@Kinder-UKE, University Medical Center Hamburg-Eppendorf (UKE), 20246, Hamburg, Germany.; German Center for Child and Adolescent Health (DZKJ), Partner Site Hamburg, University Medical Center Hamburg-Eppendorf (UKE), 20246, Hamburg, Germany., Blettenberger LE; University Children's Research@Kinder-UKE, University Medical Center Hamburg-Eppendorf (UKE), 20246, Hamburg, Germany., Laubach NC; University Children's Research@Kinder-UKE, University Medical Center Hamburg-Eppendorf (UKE), 20246, Hamburg, Germany., Küchler K; University Children's Research@Kinder-UKE, University Medical Center Hamburg-Eppendorf (UKE), 20246, Hamburg, Germany., Barroso M; University Children's Research@Kinder-UKE, University Medical Center Hamburg-Eppendorf (UKE), 20246, Hamburg, Germany.; German Center for Child and Adolescent Health (DZKJ), Partner Site Hamburg, University Medical Center Hamburg-Eppendorf (UKE), 20246, Hamburg, Germany., Uetrecht C; CSSB Centre for Structural Systems Biology, Deutsches Elektronen Synchrotron DESY and Leibniz Institute of Virology (LIV) and University of Lübeck, 22607, Hamburg, Germany.; Institute of Chemistry and Metabolomics, University of Lübeck, Lübeck, Germany., Gersting SW; University Children's Research@Kinder-UKE, University Medical Center Hamburg-Eppendorf (UKE), 20246, Hamburg, Germany. gersting@uke.de.; German Center for Child and Adolescent Health (DZKJ), Partner Site Hamburg, University Medical Center Hamburg-Eppendorf (UKE), 20246, Hamburg, Germany. gersting@uke.de.
Source: Scientific reports [Sci Rep] 2025 Oct 23; Vol. 15 (1), pp. 37168. Date of Electronic Publication: 2025 Oct 23.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Guerrero-Castillo+S%22">Guerrero-Castillo S</searchLink>; University Children's Research@Kinder-UKE, University Medical Center Hamburg-Eppendorf (UKE), 20246, Hamburg, Germany. s.guerrerocastillo@uke.de.; German Center for Child and Adolescent Health (DZKJ), Partner Site Hamburg, University Medical Center Hamburg-Eppendorf (UKE), 20246, Hamburg, Germany. s.guerrerocastillo@uke.de.<br /><searchLink fieldCode="AU" term="%22Grün+A%22">Grün A</searchLink>; CSSB Centre for Structural Systems Biology, Deutsches Elektronen Synchrotron DESY and Leibniz Institute of Virology (LIV) and University of Lübeck, 22607, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Lewandowski+N%22">Lewandowski N</searchLink>; University Children's Research@Kinder-UKE, University Medical Center Hamburg-Eppendorf (UKE), 20246, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Gundorova+P%22">Gundorova P</searchLink>; University Children's Research@Kinder-UKE, University Medical Center Hamburg-Eppendorf (UKE), 20246, Hamburg, Germany.; German Center for Child and Adolescent Health (DZKJ), Partner Site Hamburg, University Medical Center Hamburg-Eppendorf (UKE), 20246, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Blettenberger+LE%22">Blettenberger LE</searchLink>; University Children's Research@Kinder-UKE, University Medical Center Hamburg-Eppendorf (UKE), 20246, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Laubach+NC%22">Laubach NC</searchLink>; University Children's Research@Kinder-UKE, University Medical Center Hamburg-Eppendorf (UKE), 20246, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Küchler+K%22">Küchler K</searchLink>; University Children's Research@Kinder-UKE, University Medical Center Hamburg-Eppendorf (UKE), 20246, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Barroso+M%22">Barroso M</searchLink>; University Children's Research@Kinder-UKE, University Medical Center Hamburg-Eppendorf (UKE), 20246, Hamburg, Germany.; German Center for Child and Adolescent Health (DZKJ), Partner Site Hamburg, University Medical Center Hamburg-Eppendorf (UKE), 20246, Hamburg, Germany.<br /><searchLink fieldCode="AU" term="%22Uetrecht+C%22">Uetrecht C</searchLink>; CSSB Centre for Structural Systems Biology, Deutsches Elektronen Synchrotron DESY and Leibniz Institute of Virology (LIV) and University of Lübeck, 22607, Hamburg, Germany.; Institute of Chemistry and Metabolomics, University of Lübeck, Lübeck, Germany.<br /><searchLink fieldCode="AU" term="%22Gersting+SW%22">Gersting SW</searchLink>; University Children's Research@Kinder-UKE, University Medical Center Hamburg-Eppendorf (UKE), 20246, Hamburg, Germany. gersting@uke.de.; German Center for Child and Adolescent Health (DZKJ), Partner Site Hamburg, University Medical Center Hamburg-Eppendorf (UKE), 20246, Hamburg, Germany. gersting@uke.de.
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