Pharmacokinetics and tolerability of single-dose Staccato® alprazolam in adolescents with epilepsy, and population pharmacokinetic analysis to support dose selection in adolescents.
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| Title: | Pharmacokinetics and tolerability of single-dose Staccato® alprazolam in adolescents with epilepsy, and population pharmacokinetic analysis to support dose selection in adolescents. |
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| Authors: | Klein P; Department of Epilepsy, Mid-Atlantic Epilepsy and Sleep Center, Bethesda, Maryland, USA., Aungaroon G; Comprehensive Epilepsy Center, Division of Neurology, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.; Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA., Biton V; Arkansas Epilepsy Program, Little Rock, Arkansas, USA., Liow KK; Comprehensive Epilepsy Center, Hawaii Pacific Neuroscience, Honolulu, Hawaii, USA., Phillips S; Department of Neurology, Mary Bridge Children's Hospital, MultiCare Institute for Research and Innovation, Tacoma, Washington, USA., Wychowski T; Department of Neurology, University of Rochester Medical Center, Rochester, New York, USA., Sadek A; Research Institute of Orlando, Orlando, Florida, USA., Elshoff JP; Department of Global Clinical Development, UCB, Monheim am Rhein, Germany., Roebling R; Department of Global Clinical Development, UCB, Monheim am Rhein, Germany., King A; Department of Safety Risk Management, UCB, Smyrna, Georgia, USA., Rospo CC; Department of Precision Medicine, UCB, Braine-l'Alleud, Belgium., Schoemaker R; Occams Coöperatie U.A., Amstelveen, The Netherlands., Chanteux H; Department of Early Clinical Development & Translational Sciences, Patient Solutions, UCB, Braine-l'Alleud, Belgium. |
| Source: | Epilepsia [Epilepsia] 2026 Jan; Vol. 67 (1), pp. 109-119. Date of Electronic Publication: 2025 Oct 24. |
| Publication Type: | Journal Article; Multicenter Study; Clinical Trial, Phase I |
| Journal Info: | Publisher: Blackwell Science Country of Publication: United States NLM ID: 2983306R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1528-1167 (Electronic) Linking ISSN: 00139580 NLM ISO Abbreviation: Epilepsia Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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