Fentanyl exposure during preconception and gestation permanently dysregulates endogenous opioid peptides and sympathoadrenal-medullary axis in the offspring.

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Title: Fentanyl exposure during preconception and gestation permanently dysregulates endogenous opioid peptides and sympathoadrenal-medullary axis in the offspring.
Authors: Ahmed N; Department of Pharmacology and Nutritional Sciences, College of Medicine., Dalmasso C; Department of Pharmacology and Nutritional Sciences, College of Medicine., Tavakoli NS; Department of Neuroscience, College of Medicine., Peñalver Abed P; Instituto de Investigaciones Médicas M. y M. Ferreyra (INIMEC-CONICET-UNC) Universidad Nacional de Córdoba, Argentina., Turner MB; Department of Pharmacology and Nutritional Sciences, College of Medicine., Czuba LC; Department of Pharmaceutical Sciences, College of Pharmacy., Pautassi RM; Instituto de Investigaciones Médicas M. y M. Ferreyra (INIMEC-CONICET-UNC) Universidad Nacional de Córdoba, Argentina., Ortinski PI; Department of Neuroscience, College of Medicine., Loria AS; Department of Pharmacology and Nutritional Sciences, College of Medicine.; SAHA Cardiovascular Center, University of Kentucky Lexington, KY, 40536.
Source: Clinical science (London, England : 1979) [Clin Sci (Lond)] 2025 Nov 12; Vol. 139 (21), pp. 1337-1353.
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Portland Press on behalf of the Medical Research Society and the Biochemical Society Country of Publication: England NLM ID: 7905731 Publication Model: Print Cited Medium: Internet ISSN: 1470-8736 (Electronic) Linking ISSN: 01435221 NLM ISO Abbreviation: Clin Sci (Lond) Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Fentanyl exposure during preconception and gestation permanently dysregulates endogenous opioid peptides and sympathoadrenal-medullary axis in the offspring.
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  Data: <searchLink fieldCode="AU" term="%22Ahmed+N%22">Ahmed N</searchLink>; Department of Pharmacology and Nutritional Sciences, College of Medicine.<br /><searchLink fieldCode="AU" term="%22Dalmasso+C%22">Dalmasso C</searchLink>; Department of Pharmacology and Nutritional Sciences, College of Medicine.<br /><searchLink fieldCode="AU" term="%22Tavakoli+NS%22">Tavakoli NS</searchLink>; Department of Neuroscience, College of Medicine.<br /><searchLink fieldCode="AU" term="%22Peñalver+Abed+P%22">Peñalver Abed P</searchLink>; Instituto de Investigaciones Médicas M. y M. Ferreyra (INIMEC-CONICET-UNC) Universidad Nacional de Córdoba, Argentina.<br /><searchLink fieldCode="AU" term="%22Turner+MB%22">Turner MB</searchLink>; Department of Pharmacology and Nutritional Sciences, College of Medicine.<br /><searchLink fieldCode="AU" term="%22Czuba+LC%22">Czuba LC</searchLink>; Department of Pharmaceutical Sciences, College of Pharmacy.<br /><searchLink fieldCode="AU" term="%22Pautassi+RM%22">Pautassi RM</searchLink>; Instituto de Investigaciones Médicas M. y M. Ferreyra (INIMEC-CONICET-UNC) Universidad Nacional de Córdoba, Argentina.<br /><searchLink fieldCode="AU" term="%22Ortinski+PI%22">Ortinski PI</searchLink>; Department of Neuroscience, College of Medicine.<br /><searchLink fieldCode="AU" term="%22Loria+AS%22">Loria AS</searchLink>; Department of Pharmacology and Nutritional Sciences, College of Medicine.; SAHA Cardiovascular Center, University of Kentucky Lexington, KY, 40536.
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  Data: <searchLink fieldCode="JN" term="%227905731%22">Clinical science (London, England : 1979)</searchLink> [Clin Sci (Lond)] 2025 Nov 12; Vol. 139 (21), pp. 1337-1353.
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  Data: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Portland+Press+on+behalf+of+the+Medical+Research+Society+and+the+Biochemical+Society%22">Portland Press on behalf of the Medical Research Society and the Biochemical Society </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>7905731 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1470-8736 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201435221%22">01435221 </searchLink><i>NLM ISO Abbreviation: </i>Clin Sci (Lond) <i>Subsets: </i>MEDLINE
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        Value: 10.1042/CS20256962
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        Text: English
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        StartPage: 1337
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      – TitleFull: Fentanyl exposure during preconception and gestation permanently dysregulates endogenous opioid peptides and sympathoadrenal-medullary axis in the offspring.
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              Text: 2025 Nov 12
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