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PTEN Oxidation Promotes Constitutive PI3K Signaling and Inducible Macropinocytosis in Pancreatic Cancer.

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Title: PTEN Oxidation Promotes Constitutive PI3K Signaling and Inducible Macropinocytosis in Pancreatic Cancer.
Authors: Burge RA; Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, South Carolina., Bialousow L; Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, South Carolina., Linke AJ; Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, South Carolina., Coalson HS; Department of Microbiology, Immunology, and Cancer Biology, University of Virginia Health System, Charlottesville, Virginia., Adair SJ; Department of Surgery, University of Virginia, Charlottesville, Virginia., Sundararaj K; Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, South Carolina., Smith M; College of Graduate Studies, Medical University of South Carolina, Charleston, South Carolina., Bumbleburg C; College of Graduate Studies, Medical University of South Carolina, Charleston, South Carolina., Bauer TW; Department of Surgery, University of Virginia, Charlottesville, Virginia., Kashatus DF; Department of Microbiology, Immunology, and Cancer Biology, University of Virginia Health System, Charlottesville, Virginia., Hobbs GA; Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, South Carolina.; Hollings Cancer Center, Charleston, South Carolina.
Source: Cancer research [Cancer Res] 2026 Apr 15; Vol. 86 (8), pp. 1854-1867.
Publication Type: Journal Article
Journal Info: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: PTEN Oxidation Promotes Constitutive PI3K Signaling and Inducible Macropinocytosis in Pancreatic Cancer.
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  Data: <searchLink fieldCode="AU" term="%22Burge+RA%22">Burge RA</searchLink>; Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, South Carolina.<br /><searchLink fieldCode="AU" term="%22Bialousow+L%22">Bialousow L</searchLink>; Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, South Carolina.<br /><searchLink fieldCode="AU" term="%22Linke+AJ%22">Linke AJ</searchLink>; Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, South Carolina.<br /><searchLink fieldCode="AU" term="%22Coalson+HS%22">Coalson HS</searchLink>; Department of Microbiology, Immunology, and Cancer Biology, University of Virginia Health System, Charlottesville, Virginia.<br /><searchLink fieldCode="AU" term="%22Adair+SJ%22">Adair SJ</searchLink>; Department of Surgery, University of Virginia, Charlottesville, Virginia.<br /><searchLink fieldCode="AU" term="%22Sundararaj+K%22">Sundararaj K</searchLink>; Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, South Carolina.<br /><searchLink fieldCode="AU" term="%22Smith+M%22">Smith M</searchLink>; College of Graduate Studies, Medical University of South Carolina, Charleston, South Carolina.<br /><searchLink fieldCode="AU" term="%22Bumbleburg+C%22">Bumbleburg C</searchLink>; College of Graduate Studies, Medical University of South Carolina, Charleston, South Carolina.<br /><searchLink fieldCode="AU" term="%22Bauer+TW%22">Bauer TW</searchLink>; Department of Surgery, University of Virginia, Charlottesville, Virginia.<br /><searchLink fieldCode="AU" term="%22Kashatus+DF%22">Kashatus DF</searchLink>; Department of Microbiology, Immunology, and Cancer Biology, University of Virginia Health System, Charlottesville, Virginia.<br /><searchLink fieldCode="AU" term="%22Hobbs+GA%22">Hobbs GA</searchLink>; Department of Biochemistry and Molecular Biology, Medical University of South Carolina, Charleston, South Carolina.; Hollings Cancer Center, Charleston, South Carolina.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Association+for+Cancer+Research%22">American Association for Cancer Research </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>2984705R <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1538-7445 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200085472%22">00085472 </searchLink><i>NLM ISO Abbreviation: </i>Cancer Res <i>Subsets: </i>MEDLINE
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              Text: 2026 Apr 15
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