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Central nervous system involvement in CLL: an international retrospective study by ERIC, the European Research Initiative on CLL.

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Title: Central nervous system involvement in CLL: an international retrospective study by ERIC, the European Research Initiative on CLL.
Authors: Chatzikonstantinou T; Institute of Applied Biosciences, Centre for Research and Technology Hellas, Thessaloniki, Greece., Mikhaleva M; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA., Brieghel C; Department of Hematology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.; Hematology Branch, Danish Cancer Institute, Copenhagen, Denmark., Papangelou C; Institute of Applied Biosciences, Centre for Research and Technology Hellas, Thessaloniki, Greece., Minga E; Institute of Applied Biosciences, Centre for Research and Technology Hellas, Thessaloniki, Greece., Arrais-Rodrigues C; Universidade Federal de Sao Paulo, Sao Paulo, Brazil., Besikli-Dimou S; Institute of Applied Biosciences, Centre for Research and Technology Hellas, Thessaloniki, Greece., Cerutti A; Sanatorio Británico de Rosario, Santa Fe, Argentina., Doubek M; Department of Internal Medicine, Hematology and Oncology, and Institute of Medical Genetics and Genomics, University Hospital Brno and Medical Faculty Masaryk University, Brno, Czech Republic.; Centre for Molecular Medicine, Central European Institute of Technology, Masaryk University, Brno, Czech Republic., Enggaard L; Department of Hematology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark., Espinet B; Molecular Cytogenetics Laboratory, Pathology Department, Hospital del Mar and Translational Research on Hematological Neoplasms Group, Hospital del Mar Research Institute, Barcelona, Spain., Ferrer-Lores B; Department of Hematology, Hospital Clínico Universitario, Valencia, Spain., Garcia Vela JA; Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain., Gentile M; Hematology Unit, Department of Onco-Hematology, Azienda Ospedaliera of Cosenza, Cosenza, Italy.; Department of Pharmacy, Health and Nutritional Science, University of Calabria, Rende, Italy., Vázquez EG; Department of Hematology, Hospital del Mar, Barcelona, Spain., Gutwein O; Department of Hematology, Shamir Medical Center, Zerifin, Israel.; Gray Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel., Herishanu Y; Tel Aviv Sourasky Medical Center, Tel Aviv, Israel., Jablonowska-Babij P; Clinical Department of Hematology, Cell Therapies and Internal Diseases, Wroclaw Medical University, Wroclaw, Poland., Jaksic O; Division of Hematology, Department of Medicine, University Hospital Dubrava, Medical School University of Zagreb, Zagreb, Croatia., Josefsson P; Department of Hematology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark., Kalicińska E; Clinical Department of Hematology, Cell Therapies and Internal Diseases, Wroclaw Medical University, Wroclaw, Poland., Kislova M; Department of Hematology, Oncology, and Chemotherapy, S. P. Botkin's City Hospital, Moscow, Russia., Lista E; Department of Hematology, Santa Chiara Hospital, Azienda Provinciale per i Servizi Sanitari Trento, Trento, Italy., Kotsianidis I; Department of Hematology, Democritus University of Thrace, Alexandroupolis, Greece., Marquet J; Hematology Department, Ramón y Cajal University Hospital, Madrid, Spain., Martino EA; Department of Pharmacy, Health and Nutritional Science, University of Calabria, Rende, Italy., McAuley C; Department of Clinical Haematology, Peter MacCallum Cancer Centre and Royal Melbourne Hospital, Melbourne, VIC, Australia.; Department of Pathology, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.; Department of Diagnostic Haematology, Royal Melbourne Hospital, Melbourne, VIC, Australia., Mela Osorio MJ; Fundaleu, Buenos Aires, Argentina., Moia R; Division of Hematology, Department of Translational Medicine, Università del Piemonte Orientale, Novara, Italy., Mosquera C; Hematology Unit, Department of Onco-Hematology, Azienda Ospedaliera of Cosenza, Cosenza, Italy., Nikitin E; Department of Hematology, Oncology, and Chemotherapy, S. P. Botkin's City Hospital, Moscow, Russia., Pavlovsky MA; Fundaleu, Buenos Aires, Argentina., Pfister V; Universidade Federal de Sao Paulo, Sao Paulo, Brazil., Savaş EM; Department of Hematology, Gazi University Faculty of Medicine, Ankara, Turkey., Scarfò L; Università Vita-Salute San Raffaele, Milan, Italy.; Ospedale San Raffaele, Milan, Italy., Sever M; University Medical Centre, Ljubljana and Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia., Shvidel L; Institute of Hematology, Kaplan Medical Center, Rehovot, Israel., Simkovic M; 4th Department of Internal Medicine-Hematology, Faculty of Medicine in Hradec Králové, University Hospital and Charles University, Hradec Králové, Czech Republic., Stavroyianni N; Hematology Department, Papanicolaou Hospital, Thessaloniki, Greece., Talimtzi P; Institute of Applied Biosciences, Centre for Research and Technology Hellas, Thessaloniki, Greece., Tranidou A; Institute of Applied Biosciences, Centre for Research and Technology Hellas, Thessaloniki, Greece., Visentin A; Hematology Unit, Department of Medicine, University of Padua, Padua, Italy., Vrachiolias G; Department of Hematology, Democritus University of Thrace, Alexandroupolis, Greece., Wasik-Szczepanek E; Department of Hematooncology and Bone Marrow Transplantation, Medical University in Lublin, Lublin, Poland., Wróbel T; Clinical Department of Hematology, Cell Therapies and Internal Diseases, Wroclaw Medical University, Wroclaw, Poland., Yağcı M; Department of Hematology, Gazi University Faculty of Medicine, Ankara, Turkey., Cellini A; Hematology Unit, Department of Medicine, University of Padua, Padua, Italy., Chatzidimitriou A; Institute of Applied Biosciences, Centre for Research and Technology Hellas, Thessaloniki, Greece., Gaidano G; Division of Hematology, Department of Translational Medicine, Università del Piemonte Orientale, Novara, Italy., Anderson MA; Department of Clinical Haematology, Peter MacCallum Cancer Centre and Royal Melbourne Hospital, Melbourne, VIC, Australia.; Division of Blood Cells and Blood Cancer, Walter and Eliza Hall Institute, Melbourne, VIC, Australia.; Department of Medical Biology, The University of Melbourne, Melbourne, VIC, Australia., Davids MS; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA., Brown JR; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA., Niemann CU; Department of Hematology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.; Hematology Branch, Danish Cancer Institute, Copenhagen, Denmark., Stamatopoulos K; Institute of Applied Biosciences, Centre for Research and Technology Hellas, Thessaloniki, Greece., Ghia P; Università Vita-Salute San Raffaele, Milan, Italy.; Ospedale San Raffaele, Milan, Italy., Ahn IE; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA., Koren-Michowitz M; Department of Hematology, Shamir Medical Center, Zerifin, Israel.; Gray Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Source: Blood advances [Blood Adv] 2026 Jan 27; Vol. 10 (2), pp. 428-438.
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: American Society of Hematology Country of Publication: United States NLM ID: 101698425 Publication Model: Print Cited Medium: Internet ISSN: 2473-9537 (Electronic) Linking ISSN: 24739529 NLM ISO Abbreviation: Blood Adv Subsets: MEDLINE
Database: MEDLINE Ultimate
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PubType: Academic Journal
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  Data: Central nervous system involvement in CLL: an international retrospective study by ERIC, the European Research Initiative on CLL.
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  Data: <searchLink fieldCode="AU" term="%22Chatzikonstantinou+T%22">Chatzikonstantinou T</searchLink>; Institute of Applied Biosciences, Centre for Research and Technology Hellas, Thessaloniki, Greece.<br /><searchLink fieldCode="AU" term="%22Mikhaleva+M%22">Mikhaleva M</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Brieghel+C%22">Brieghel C</searchLink>; Department of Hematology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.; Hematology Branch, Danish Cancer Institute, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Papangelou+C%22">Papangelou C</searchLink>; Institute of Applied Biosciences, Centre for Research and Technology Hellas, Thessaloniki, Greece.<br /><searchLink fieldCode="AU" term="%22Minga+E%22">Minga E</searchLink>; Institute of Applied Biosciences, Centre for Research and Technology Hellas, Thessaloniki, Greece.<br /><searchLink fieldCode="AU" term="%22Arrais-Rodrigues+C%22">Arrais-Rodrigues C</searchLink>; Universidade Federal de Sao Paulo, Sao Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Besikli-Dimou+S%22">Besikli-Dimou S</searchLink>; Institute of Applied Biosciences, Centre for Research and Technology Hellas, Thessaloniki, Greece.<br /><searchLink fieldCode="AU" term="%22Cerutti+A%22">Cerutti A</searchLink>; Sanatorio Británico de Rosario, Santa Fe, Argentina.<br /><searchLink fieldCode="AU" term="%22Doubek+M%22">Doubek M</searchLink>; Department of Internal Medicine, Hematology and Oncology, and Institute of Medical Genetics and Genomics, University Hospital Brno and Medical Faculty Masaryk University, Brno, Czech Republic.; Centre for Molecular Medicine, Central European Institute of Technology, Masaryk University, Brno, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Enggaard+L%22">Enggaard L</searchLink>; Department of Hematology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Espinet+B%22">Espinet B</searchLink>; Molecular Cytogenetics Laboratory, Pathology Department, Hospital del Mar and Translational Research on Hematological Neoplasms Group, Hospital del Mar Research Institute, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Ferrer-Lores+B%22">Ferrer-Lores B</searchLink>; Department of Hematology, Hospital Clínico Universitario, Valencia, Spain.<br /><searchLink fieldCode="AU" term="%22Garcia+Vela+JA%22">Garcia Vela JA</searchLink>; Hospital Universitario Puerta de Hierro Majadahonda, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Gentile+M%22">Gentile M</searchLink>; Hematology Unit, Department of Onco-Hematology, Azienda Ospedaliera of Cosenza, Cosenza, Italy.; Department of Pharmacy, Health and Nutritional Science, University of Calabria, Rende, Italy.<br /><searchLink fieldCode="AU" term="%22Vázquez+EG%22">Vázquez EG</searchLink>; Department of Hematology, Hospital del Mar, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Gutwein+O%22">Gutwein O</searchLink>; Department of Hematology, Shamir Medical Center, Zerifin, Israel.; Gray Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.<br /><searchLink fieldCode="AU" term="%22Herishanu+Y%22">Herishanu Y</searchLink>; Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.<br /><searchLink fieldCode="AU" term="%22Jablonowska-Babij+P%22">Jablonowska-Babij P</searchLink>; Clinical Department of Hematology, Cell Therapies and Internal Diseases, Wroclaw Medical University, Wroclaw, Poland.<br /><searchLink fieldCode="AU" term="%22Jaksic+O%22">Jaksic O</searchLink>; Division of Hematology, Department of Medicine, University Hospital Dubrava, Medical School University of Zagreb, Zagreb, Croatia.<br /><searchLink fieldCode="AU" term="%22Josefsson+P%22">Josefsson P</searchLink>; Department of Hematology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Kalicińska+E%22">Kalicińska E</searchLink>; Clinical Department of Hematology, Cell Therapies and Internal Diseases, Wroclaw Medical University, Wroclaw, Poland.<br /><searchLink fieldCode="AU" term="%22Kislova+M%22">Kislova M</searchLink>; Department of Hematology, Oncology, and Chemotherapy, S. 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Botkin's City Hospital, Moscow, Russia.<br /><searchLink fieldCode="AU" term="%22Lista+E%22">Lista E</searchLink>; Department of Hematology, Santa Chiara Hospital, Azienda Provinciale per i Servizi Sanitari Trento, Trento, Italy.<br /><searchLink fieldCode="AU" term="%22Kotsianidis+I%22">Kotsianidis I</searchLink>; Department of Hematology, Democritus University of Thrace, Alexandroupolis, Greece.<br /><searchLink fieldCode="AU" term="%22Marquet+J%22">Marquet J</searchLink>; Hematology Department, Ramón y Cajal University Hospital, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Martino+EA%22">Martino EA</searchLink>; Department of Pharmacy, Health and Nutritional Science, University of Calabria, Rende, Italy.<br /><searchLink fieldCode="AU" term="%22McAuley+C%22">McAuley C</searchLink>; Department of Clinical Haematology, Peter MacCallum Cancer Centre and Royal Melbourne Hospital, Melbourne, VIC, Australia.; Department of Pathology, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.; Department of Diagnostic Haematology, Royal Melbourne Hospital, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Mela+Osorio+MJ%22">Mela Osorio MJ</searchLink>; Fundaleu, Buenos Aires, Argentina.<br /><searchLink fieldCode="AU" term="%22Moia+R%22">Moia R</searchLink>; Division of Hematology, Department of Translational Medicine, Università del Piemonte Orientale, Novara, Italy.<br /><searchLink fieldCode="AU" term="%22Mosquera+C%22">Mosquera C</searchLink>; Hematology Unit, Department of Onco-Hematology, Azienda Ospedaliera of Cosenza, Cosenza, Italy.<br /><searchLink fieldCode="AU" term="%22Nikitin+E%22">Nikitin E</searchLink>; Department of Hematology, Oncology, and Chemotherapy, S. 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Botkin's City Hospital, Moscow, Russia.<br /><searchLink fieldCode="AU" term="%22Pavlovsky+MA%22">Pavlovsky MA</searchLink>; Fundaleu, Buenos Aires, Argentina.<br /><searchLink fieldCode="AU" term="%22Pfister+V%22">Pfister V</searchLink>; Universidade Federal de Sao Paulo, Sao Paulo, Brazil.<br /><searchLink fieldCode="AU" term="%22Savaş+EM%22">Savaş EM</searchLink>; Department of Hematology, Gazi University Faculty of Medicine, Ankara, Turkey.<br /><searchLink fieldCode="AU" term="%22Scarfò+L%22">Scarfò L</searchLink>; Università Vita-Salute San Raffaele, Milan, Italy.; Ospedale San Raffaele, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Sever+M%22">Sever M</searchLink>; University Medical Centre, Ljubljana and Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.<br /><searchLink fieldCode="AU" term="%22Shvidel+L%22">Shvidel L</searchLink>; Institute of Hematology, Kaplan Medical Center, Rehovot, Israel.<br /><searchLink fieldCode="AU" term="%22Simkovic+M%22">Simkovic M</searchLink>; 4th Department of Internal Medicine-Hematology, Faculty of Medicine in Hradec Králové, University Hospital and Charles University, Hradec Králové, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Stavroyianni+N%22">Stavroyianni N</searchLink>; Hematology Department, Papanicolaou Hospital, Thessaloniki, Greece.<br /><searchLink fieldCode="AU" term="%22Talimtzi+P%22">Talimtzi P</searchLink>; Institute of Applied Biosciences, Centre for Research and Technology Hellas, Thessaloniki, Greece.<br /><searchLink fieldCode="AU" term="%22Tranidou+A%22">Tranidou A</searchLink>; Institute of Applied Biosciences, Centre for Research and Technology Hellas, Thessaloniki, Greece.<br /><searchLink fieldCode="AU" term="%22Visentin+A%22">Visentin A</searchLink>; Hematology Unit, Department of Medicine, University of Padua, Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Vrachiolias+G%22">Vrachiolias G</searchLink>; Department of Hematology, Democritus University of Thrace, Alexandroupolis, Greece.<br /><searchLink fieldCode="AU" term="%22Wasik-Szczepanek+E%22">Wasik-Szczepanek E</searchLink>; Department of Hematooncology and Bone Marrow Transplantation, Medical University in Lublin, Lublin, Poland.<br /><searchLink fieldCode="AU" term="%22Wróbel+T%22">Wróbel T</searchLink>; Clinical Department of Hematology, Cell Therapies and Internal Diseases, Wroclaw Medical University, Wroclaw, Poland.<br /><searchLink fieldCode="AU" term="%22Yağcı+M%22">Yağcı M</searchLink>; Department of Hematology, Gazi University Faculty of Medicine, Ankara, Turkey.<br /><searchLink fieldCode="AU" term="%22Cellini+A%22">Cellini A</searchLink>; Hematology Unit, Department of Medicine, University of Padua, Padua, Italy.<br /><searchLink fieldCode="AU" term="%22Chatzidimitriou+A%22">Chatzidimitriou A</searchLink>; Institute of Applied Biosciences, Centre for Research and Technology Hellas, Thessaloniki, Greece.<br /><searchLink fieldCode="AU" term="%22Gaidano+G%22">Gaidano G</searchLink>; Division of Hematology, Department of Translational Medicine, Università del Piemonte Orientale, Novara, Italy.<br /><searchLink fieldCode="AU" term="%22Anderson+MA%22">Anderson MA</searchLink>; Department of Clinical Haematology, Peter MacCallum Cancer Centre and Royal Melbourne Hospital, Melbourne, VIC, Australia.; Division of Blood Cells and Blood Cancer, Walter and Eliza Hall Institute, Melbourne, VIC, Australia.; Department of Medical Biology, The University of Melbourne, Melbourne, VIC, Australia.<br /><searchLink fieldCode="AU" term="%22Davids+MS%22">Davids MS</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Brown+JR%22">Brown JR</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Niemann+CU%22">Niemann CU</searchLink>; Department of Hematology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.; Hematology Branch, Danish Cancer Institute, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Stamatopoulos+K%22">Stamatopoulos K</searchLink>; Institute of Applied Biosciences, Centre for Research and Technology Hellas, Thessaloniki, Greece.<br /><searchLink fieldCode="AU" term="%22Ghia+P%22">Ghia P</searchLink>; Università Vita-Salute San Raffaele, Milan, Italy.; Ospedale San Raffaele, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Ahn+IE%22">Ahn IE</searchLink>; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA.<br /><searchLink fieldCode="AU" term="%22Koren-Michowitz+M%22">Koren-Michowitz M</searchLink>; Department of Hematology, Shamir Medical Center, Zerifin, Israel.; Gray Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
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            NameFull: Gaidano G
      – PersonEntity:
          Name:
            NameFull: Anderson MA
      – PersonEntity:
          Name:
            NameFull: Davids MS
      – PersonEntity:
          Name:
            NameFull: Brown JR
      – PersonEntity:
          Name:
            NameFull: Niemann CU
      – PersonEntity:
          Name:
            NameFull: Stamatopoulos K
      – PersonEntity:
          Name:
            NameFull: Ghia P
      – PersonEntity:
          Name:
            NameFull: Ahn IE
      – PersonEntity:
          Name:
            NameFull: Koren-Michowitz M
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 27
              M: 01
              Text: 2026 Jan 27
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 2473-9537
          Numbering:
            – Type: volume
              Value: 10
            – Type: issue
              Value: 2
          Titles:
            – TitleFull: Blood advances
              Type: main
ResultId 1