Distinctive patterns of G protein coupling induced by the structurally similar 5-HT2A receptor ligands ketanserin and altanserin in human prefrontal cortex.
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| Title: | Distinctive patterns of G protein coupling induced by the structurally similar 5-HT |
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| Authors: | Miranda-Azpiazu P; Department of Pharmacology, University of the Basque Country UPV/EHU, Leioa, Bizkaia, Spain., Muguruza C; Department of Pharmacology, University of the Basque Country UPV/EHU, Leioa, Bizkaia, Spain; Centro de Investigación Biomédica en Red de Salud Mental CIBERSAM, ISCIII, Spain., Stepniewski TM; Research Programme on Biomedical Informatics, Hospital del Mar Research Institute, Department of Medicine and Life Sciences, Pompeu Fabra University, Barcelona, Spain; InterAx Biotech AG, PARK InnovAARE, Villigen, Switzerland; Faculty of Chemistry, Biological and Chemical Research Centre, University of Warsaw, Warsaw, Poland., Muneta-Arrate I; Department of Pharmacology, University of the Basque Country UPV/EHU, Leioa, Bizkaia, Spain; Centro de Investigación Biomédica en Red de Salud Mental CIBERSAM, ISCIII, Spain., Moreira D; Innopharma Drug Screening and Pharmacogenomics Platform, BioFarma Research Group, Center for Research in Molecular Medicine and Chronic Diseases (CiMUS), Department of Pharmacology, Pharmacy and Pharmaceutical Technology, Faculty of Pharmacy, University of Santiago de Compostela, Santiago de Compostela, Spain; Kaertor Foundation, Santiago de Compostela, Spain., Brea J; Innopharma Drug Screening and Pharmacogenomics Platform, BioFarma Research Group, Center for Research in Molecular Medicine and Chronic Diseases (CiMUS), Department of Pharmacology, Pharmacy and Pharmaceutical Technology, Faculty of Pharmacy, University of Santiago de Compostela, Santiago de Compostela, Spain; Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), Santiago de Compostela, Spain., Callado LF; Department of Pharmacology, University of the Basque Country UPV/EHU, Leioa, Bizkaia, Spain; Centro de Investigación Biomédica en Red de Salud Mental CIBERSAM, ISCIII, Spain; Biobizkaia Health Research Institute, Barakaldo, Bizkaia, Spain., Loza MI; Innopharma Drug Screening and Pharmacogenomics Platform, BioFarma Research Group, Center for Research in Molecular Medicine and Chronic Diseases (CiMUS), Department of Pharmacology, Pharmacy and Pharmaceutical Technology, Faculty of Pharmacy, University of Santiago de Compostela, Santiago de Compostela, Spain; Kaertor Foundation, Santiago de Compostela, Spain; Instituto de Investigación Sanitaria de Santiago de Compostela (IDIS), Santiago de Compostela, Spain., González-Maeso J; Department of Physiology and Biophysics, Virginia Commonwealth University School of Medicine, Richmond, Virginia., Selent J; Research Programme on Biomedical Informatics, Hospital del Mar Research Institute, Department of Medicine and Life Sciences, Pompeu Fabra University, Barcelona, Spain., Diez-Alarcia R; Department of Pharmacology, University of the Basque Country UPV/EHU, Leioa, Bizkaia, Spain; Centro de Investigación Biomédica en Red de Salud Mental CIBERSAM, ISCIII, Spain; Biobizkaia Health Research Institute, Barakaldo, Bizkaia, Spain., Meana JJ; Department of Pharmacology, University of the Basque Country UPV/EHU, Leioa, Bizkaia, Spain; Centro de Investigación Biomédica en Red de Salud Mental CIBERSAM, ISCIII, Spain; Biobizkaia Health Research Institute, Barakaldo, Bizkaia, Spain. Electronic address: javier.meana@ehu.eus. |
| Source: | Molecular pharmacology [Mol Pharmacol] 2025 Nov; Vol. 107 (11), pp. 100075. Date of Electronic Publication: 2025 Sep 24. |
| Publication Type: | Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural |
| Journal Info: | Publisher: American Society for Pharmacology and Experimental Therapeutics Country of Publication: Netherlands NLM ID: 0035623 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-0111 (Electronic) Linking ISSN: 0026895X NLM ISO Abbreviation: Mol Pharmacol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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