Macrocyclic peptides targeting human CD44 inhibit cell adhesion.

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Title: Macrocyclic peptides targeting human CD44 inhibit cell adhesion.
Authors: Chatzopoulos A; Department of Medical Biochemistry and Microbiology, Uppsala University, SE-751 23 Uppsala, Sweden; Biochemistry, Biochemical Analysis & Matrix Pathobiology Res. Group, Laboratory of Biochemistry, Department of Chemistry, University of Patras, 26504 Patras, Greece., Kolliopoulos C; Department of Medical Biochemistry and Microbiology, Uppsala University, SE-751 23 Uppsala, Sweden., Yin Y; Department of Chemistry, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan; State Key Laboratory of Microbial Technology, Shandong University, Qingdao 266237, China., Karalis T; Department of Medical Biochemistry and Microbiology, Uppsala University, SE-751 23 Uppsala, Sweden., Komine A; Department of Experimental Pathology, Graduate School of Comprehensive Human Sciences and Faculty of Medicine, University of Tsukuba, Ibaraki, Japan., PhuongDung Tran ST; Human Biology, School of Integrative and Global Majors, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Japan; Department of Experimental Pathology, Faculty of Medicine, University of Tsukuba, Japan., Hwang J; Human Biology, School of Integrative and Global Majors, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Japan; Department of Oncology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105-3678, USA; Department of Experimental Pathology, Faculty of Medicine, University of Tsukuba, Japan., Goto N; Human Biology, School of Integrative and Global Majors, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Japan; Asahi Kasei Pharma, Izunokuni-shi, Shizuoka, Japan; Department of Experimental Pathology, Faculty of Medicine, University of Tsukuba, Japan., Suga H; Department of Chemistry, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan., Ten Dijke P; Department of Cancer Signaling, Graduate School of Comprehensive Human Sciences and Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan; Oncode Institute and Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, the Netherlands., Hipolito CJ; Department of Cancer Signaling, Graduate School of Comprehensive Human Sciences and Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan. Electronic address: chris.john.hipolito@gmail.com., Skandalis SS; Biochemistry, Biochemical Analysis & Matrix Pathobiology Res. Group, Laboratory of Biochemistry, Department of Chemistry, University of Patras, 26504 Patras, Greece. Electronic address: skandalis@upatras.gr., Heldin P; Department of Medical Biochemistry and Microbiology, Uppsala University, SE-751 23 Uppsala, Sweden. Electronic address: evi.heldin@imbim.uu.se.
Source: Cellular signalling [Cell Signal] 2025 Dec; Vol. 136, pp. 112178. Date of Electronic Publication: 2025 Oct 22.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 8904683 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3913 (Electronic) Linking ISSN: 08986568 NLM ISO Abbreviation: Cell Signal Subsets: MEDLINE
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  Data: Macrocyclic peptides targeting human CD44 inhibit cell adhesion.
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  Data: <searchLink fieldCode="AU" term="%22Chatzopoulos+A%22">Chatzopoulos A</searchLink>; Department of Medical Biochemistry and Microbiology, Uppsala University, SE-751 23 Uppsala, Sweden; Biochemistry, Biochemical Analysis & Matrix Pathobiology Res. Group, Laboratory of Biochemistry, Department of Chemistry, University of Patras, 26504 Patras, Greece.<br /><searchLink fieldCode="AU" term="%22Kolliopoulos+C%22">Kolliopoulos C</searchLink>; Department of Medical Biochemistry and Microbiology, Uppsala University, SE-751 23 Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Yin+Y%22">Yin Y</searchLink>; Department of Chemistry, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan; State Key Laboratory of Microbial Technology, Shandong University, Qingdao 266237, China.<br /><searchLink fieldCode="AU" term="%22Karalis+T%22">Karalis T</searchLink>; Department of Medical Biochemistry and Microbiology, Uppsala University, SE-751 23 Uppsala, Sweden.<br /><searchLink fieldCode="AU" term="%22Komine+A%22">Komine A</searchLink>; Department of Experimental Pathology, Graduate School of Comprehensive Human Sciences and Faculty of Medicine, University of Tsukuba, Ibaraki, Japan.<br /><searchLink fieldCode="AU" term="%22PhuongDung+Tran+ST%22">PhuongDung Tran ST</searchLink>; Human Biology, School of Integrative and Global Majors, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Japan; Department of Experimental Pathology, Faculty of Medicine, University of Tsukuba, Japan.<br /><searchLink fieldCode="AU" term="%22Hwang+J%22">Hwang J</searchLink>; Human Biology, School of Integrative and Global Majors, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Japan; Department of Oncology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105-3678, USA; Department of Experimental Pathology, Faculty of Medicine, University of Tsukuba, Japan.<br /><searchLink fieldCode="AU" term="%22Goto+N%22">Goto N</searchLink>; Human Biology, School of Integrative and Global Majors, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Japan; Asahi Kasei Pharma, Izunokuni-shi, Shizuoka, Japan; Department of Experimental Pathology, Faculty of Medicine, University of Tsukuba, Japan.<br /><searchLink fieldCode="AU" term="%22Suga+H%22">Suga H</searchLink>; Department of Chemistry, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan.<br /><searchLink fieldCode="AU" term="%22Ten+Dijke+P%22">Ten Dijke P</searchLink>; Department of Cancer Signaling, Graduate School of Comprehensive Human Sciences and Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan; Oncode Institute and Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Hipolito+CJ%22">Hipolito CJ</searchLink>; Department of Cancer Signaling, Graduate School of Comprehensive Human Sciences and Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan. Electronic address: chris.john.hipolito@gmail.com.<br /><searchLink fieldCode="AU" term="%22Skandalis+SS%22">Skandalis SS</searchLink>; Biochemistry, Biochemical Analysis & Matrix Pathobiology Res. Group, Laboratory of Biochemistry, Department of Chemistry, University of Patras, 26504 Patras, Greece. Electronic address: skandalis@upatras.gr.<br /><searchLink fieldCode="AU" term="%22Heldin+P%22">Heldin P</searchLink>; Department of Medical Biochemistry and Microbiology, Uppsala University, SE-751 23 Uppsala, Sweden. Electronic address: evi.heldin@imbim.uu.se.
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  Data: <searchLink fieldCode="JN" term="%228904683%22">Cellular signalling</searchLink> [Cell Signal] 2025 Dec; Vol. 136, pp. 112178. <i>Date of Electronic Publication: </i>2025 Oct 22.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Science+Ltd%22">Elsevier Science Ltd </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>8904683 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1873-3913 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2208986568%22">08986568 </searchLink><i>NLM ISO Abbreviation: </i>Cell Signal <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.cellsig.2025.112178
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              Text: 2025 Dec
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