Macrocyclic peptides targeting human CD44 inhibit cell adhesion.

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Title: Macrocyclic peptides targeting human CD44 inhibit cell adhesion.
Authors: Chatzopoulos A; Department of Medical Biochemistry and Microbiology, Uppsala University, SE-751 23 Uppsala, Sweden; Biochemistry, Biochemical Analysis & Matrix Pathobiology Res. Group, Laboratory of Biochemistry, Department of Chemistry, University of Patras, 26504 Patras, Greece., Kolliopoulos C; Department of Medical Biochemistry and Microbiology, Uppsala University, SE-751 23 Uppsala, Sweden., Yin Y; Department of Chemistry, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan; State Key Laboratory of Microbial Technology, Shandong University, Qingdao 266237, China., Karalis T; Department of Medical Biochemistry and Microbiology, Uppsala University, SE-751 23 Uppsala, Sweden., Komine A; Department of Experimental Pathology, Graduate School of Comprehensive Human Sciences and Faculty of Medicine, University of Tsukuba, Ibaraki, Japan., PhuongDung Tran ST; Human Biology, School of Integrative and Global Majors, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Japan; Department of Experimental Pathology, Faculty of Medicine, University of Tsukuba, Japan., Hwang J; Human Biology, School of Integrative and Global Majors, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Japan; Department of Oncology, St. Jude Children's Research Hospital, 262 Danny Thomas Place, Memphis, TN 38105-3678, USA; Department of Experimental Pathology, Faculty of Medicine, University of Tsukuba, Japan., Goto N; Human Biology, School of Integrative and Global Majors, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Japan; Asahi Kasei Pharma, Izunokuni-shi, Shizuoka, Japan; Department of Experimental Pathology, Faculty of Medicine, University of Tsukuba, Japan., Suga H; Department of Chemistry, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan., Ten Dijke P; Department of Cancer Signaling, Graduate School of Comprehensive Human Sciences and Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan; Oncode Institute and Department of Cell and Chemical Biology, Leiden University Medical Center, Leiden, the Netherlands., Hipolito CJ; Department of Cancer Signaling, Graduate School of Comprehensive Human Sciences and Faculty of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan. Electronic address: chris.john.hipolito@gmail.com., Skandalis SS; Biochemistry, Biochemical Analysis & Matrix Pathobiology Res. Group, Laboratory of Biochemistry, Department of Chemistry, University of Patras, 26504 Patras, Greece. Electronic address: skandalis@upatras.gr., Heldin P; Department of Medical Biochemistry and Microbiology, Uppsala University, SE-751 23 Uppsala, Sweden. Electronic address: evi.heldin@imbim.uu.se.
Source: Cellular signalling [Cell Signal] 2025 Dec; Vol. 136, pp. 112178. Date of Electronic Publication: 2025 Oct 22.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 8904683 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3913 (Electronic) Linking ISSN: 08986568 NLM ISO Abbreviation: Cell Signal Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1873-3913
DOI:10.1016/j.cellsig.2025.112178