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Restoration of sFRP3 Preserves the Neural Stem Cell Pool and Spatial Discrimination Ability in a Mouse Model of Alzheimer's Disease.

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Title: Restoration of sFRP3 Preserves the Neural Stem Cell Pool and Spatial Discrimination Ability in a Mouse Model of Alzheimer's Disease.
Authors: Fu CH; Department of Neuroscience, Baylor College of Medicine, Houston, Texas 77030.; Department of Neuroscience, Thomas Jefferson University, Philadelphia, Pennsylvania 19107., Park J; Department of Neuroscience, Baylor College of Medicine, Houston, Texas 77030., Tosi U; Department of Neuroscience, Thomas Jefferson University, Philadelphia, Pennsylvania 19107., Blanco FA; Department of Neuroscience, Baylor College of Medicine, Houston, Texas 77030., Silva-Pérez M; Department of Neuroscience, Baylor College of Medicine, Houston, Texas 77030., Muralidharan K; Department of Neuroscience, Baylor College of Medicine, Houston, Texas 77030., You JC; Department of Neuroscience, Baylor College of Medicine, Houston, Texas 77030.; Department of Neuroscience, Thomas Jefferson University, Philadelphia, Pennsylvania 19107., Lee M; Department of Neuroscience, Baylor College of Medicine, Houston, Texas 77030., Stephens GS; Department of Neuroscience, Baylor College of Medicine, Houston, Texas 77030.; Center for Dementia Research, Nathan Kline Institute for Psychiatric Research, Orangeburg, New York 10962., Zhang X; Department of Neuroscience, Thomas Jefferson University, Philadelphia, Pennsylvania 19107., Zheng Y; Department of Neuroscience, Baylor College of Medicine, Houston, Texas 77030., Scharfman H; Center for Dementia Research, Nathan Kline Institute for Psychiatric Research, Orangeburg, New York 10962.; Department of Child & Adolescent Psychiatry, Neuroscience & Physiology, and Psychiatry, New York University Neuroscience Institute, New York University Langone Health, New York City, New York 10016., Tolias KF; Department of Neuroscience, Baylor College of Medicine, Houston, Texas 77030., Chin J; Department of Neuroscience, Baylor College of Medicine, Houston, Texas 77030 jeannie.chin@bcm.edu.; Department of Neuroscience, Thomas Jefferson University, Philadelphia, Pennsylvania 19107.
Source: The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2025 Dec 03; Vol. 45 (49). Date of Electronic Publication: 2025 Dec 03.
Publication Type: Journal Article; Research Support, N.I.H., Extramural
Journal Info: Publisher: Society for Neuroscience Country of Publication: United States NLM ID: 8102140 Publication Model: Electronic Cited Medium: Internet ISSN: 1529-2401 (Electronic) Linking ISSN: 02706474 NLM ISO Abbreviation: J Neurosci Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Restoration of sFRP3 Preserves the Neural Stem Cell Pool and Spatial Discrimination Ability in a Mouse Model of Alzheimer's Disease.
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  Data: <searchLink fieldCode="AU" term="%22Fu+CH%22">Fu CH</searchLink>; Department of Neuroscience, Baylor College of Medicine, Houston, Texas 77030.; Department of Neuroscience, Thomas Jefferson University, Philadelphia, Pennsylvania 19107.<br /><searchLink fieldCode="AU" term="%22Park+J%22">Park J</searchLink>; Department of Neuroscience, Baylor College of Medicine, Houston, Texas 77030.<br /><searchLink fieldCode="AU" term="%22Tosi+U%22">Tosi U</searchLink>; Department of Neuroscience, Thomas Jefferson University, Philadelphia, Pennsylvania 19107.<br /><searchLink fieldCode="AU" term="%22Blanco+FA%22">Blanco FA</searchLink>; Department of Neuroscience, Baylor College of Medicine, Houston, Texas 77030.<br /><searchLink fieldCode="AU" term="%22Silva-Pérez+M%22">Silva-Pérez M</searchLink>; Department of Neuroscience, Baylor College of Medicine, Houston, Texas 77030.<br /><searchLink fieldCode="AU" term="%22Muralidharan+K%22">Muralidharan K</searchLink>; Department of Neuroscience, Baylor College of Medicine, Houston, Texas 77030.<br /><searchLink fieldCode="AU" term="%22You+JC%22">You JC</searchLink>; Department of Neuroscience, Baylor College of Medicine, Houston, Texas 77030.; Department of Neuroscience, Thomas Jefferson University, Philadelphia, Pennsylvania 19107.<br /><searchLink fieldCode="AU" term="%22Lee+M%22">Lee M</searchLink>; Department of Neuroscience, Baylor College of Medicine, Houston, Texas 77030.<br /><searchLink fieldCode="AU" term="%22Stephens+GS%22">Stephens GS</searchLink>; Department of Neuroscience, Baylor College of Medicine, Houston, Texas 77030.; Center for Dementia Research, Nathan Kline Institute for Psychiatric Research, Orangeburg, New York 10962.<br /><searchLink fieldCode="AU" term="%22Zhang+X%22">Zhang X</searchLink>; Department of Neuroscience, Thomas Jefferson University, Philadelphia, Pennsylvania 19107.<br /><searchLink fieldCode="AU" term="%22Zheng+Y%22">Zheng Y</searchLink>; Department of Neuroscience, Baylor College of Medicine, Houston, Texas 77030.<br /><searchLink fieldCode="AU" term="%22Scharfman+H%22">Scharfman H</searchLink>; Center for Dementia Research, Nathan Kline Institute for Psychiatric Research, Orangeburg, New York 10962.; Department of Child & Adolescent Psychiatry, Neuroscience & Physiology, and Psychiatry, New York University Neuroscience Institute, New York University Langone Health, New York City, New York 10016.<br /><searchLink fieldCode="AU" term="%22Tolias+KF%22">Tolias KF</searchLink>; Department of Neuroscience, Baylor College of Medicine, Houston, Texas 77030.<br /><searchLink fieldCode="AU" term="%22Chin+J%22">Chin J</searchLink>; Department of Neuroscience, Baylor College of Medicine, Houston, Texas 77030 jeannie.chin@bcm.edu.; Department of Neuroscience, Thomas Jefferson University, Philadelphia, Pennsylvania 19107.
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  Data: <searchLink fieldCode="JN" term="%228102140%22">The Journal of neuroscience : the official journal of the Society for Neuroscience</searchLink> [J Neurosci] 2025 Dec 03; Vol. 45 (49). <i>Date of Electronic Publication: </i>2025 Dec 03.
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