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Post-traumatic stress and genetic interactions affect tobacco and alcohol use after trauma: findings from a multi-ancestry cohort.

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Title: Post-traumatic stress and genetic interactions affect tobacco and alcohol use after trauma: findings from a multi-ancestry cohort.
Authors: Garrison-Desany HM; Department of Social and Behavioral Sciences, Harvard T.H. Chan School of Public Health, Boston, MA, USA. mgarris7@jhu.edu., Hinojosa CA; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USA., Tubbs JD; Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.; Psychiatric and Neurodevelopmental Genetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute, Boston, MA, USA., Meyers JL; Department of Psychiatry and Behavioral Sciences, State University of New York Downstate Medical Center, New York, NY, USA., Linnstaedt SD; Institute for Trauma Recovery, Department of Anesthesiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., House SL; Department of Emergency Medicine, Washington University School of Medicine, St. Louis, MO, USA., Beaudoin FL; Department of Epidemiology, Brown University, Providence, RI, USA.; Department of Emergency Medicine, Brown University, Providence, RI, USA., An X; Institute for Trauma Recovery, Department of Anesthesiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Stevens JS; Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, GA, USA., Neylan TC; Departments of Psychiatry and Neurology, University of California San Francisco, San Francisco, CA, USA., Clifford GD; Department of Biomedical Informatics, Emory University School of Medicine, Atlanta, GA, USA.; Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, Atlanta, GA, USA., Germine LT; Institute for Technology in Psychiatry, McLean Hospital, Belmont, MA, USA.; The Many Brains Project, Belmont, MA, USA.; Department of Psychiatry, Harvard Medical School, Boston, MA, USA., Rauch SL; Institute for Technology in Psychiatry, McLean Hospital, Belmont, MA, USA.; Department of Psychiatry, Harvard Medical School, Boston, MA, USA.; Department of Psychiatry, McLean Hospital, Belmont, MA, USA., Haran JP; Department of Emergency Medicine, University of Massachusetts Chan Medical School, Worcester, MA, USA., Storrow AB; Department of Emergency Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Musey PI Jr; Department of Emergency Medicine, Indiana University School of Medicine, Indianapolis, IN, USA., Hendry PL; Department of Emergency Medicine, University of Florida College of Medicine -Jacksonville, Jacksonville, FL, USA., Sheikh S; Department of Emergency Medicine, University of Florida College of Medicine -Jacksonville, Jacksonville, FL, USA., Jones CW; Department of Emergency Medicine, Cooper Medical School of Rowan University, Camden, NJ, USA., Punches BE; Department of Emergency Medicine, Ohio State University College of Medicine, Columbus, OH, USA.; Ohio State University College of Nursing, Columbus, OH, USA., Pascual JL; Department of Surgery, Department of Neurosurgery, University of Pennsylvania, Philadelphia, PA, USA.; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Seamon MJ; Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Department of Surgery, Division of Traumatology, Surgical Critical Care and Emergency Surgery, University of Pennsylvania, Philadelphia, PA, USA., Harris E; Department of Emergency Medicine, Einstein Medical Center, Philadelphia, PA, USA., Pearson C; Department of Emergency Medicine, Wayne State University, Ascension St. John Hospital, Detroit, MI, USA., Peak DA; Department of Emergency Medicine, Massachusetts General Hospital, Boston, MA, USA.; Department of Emergency Medicine, Harvard Medical School, Boston, MA, USA., Merchant RC; Department of Emergency Medicine, Brigham and Women's Hospital, Boston, MA, USA., Domeier RM; Department of Emergency Medicine, Trinity Health-Ann Arbor, Ypsilanti, MI, USA., O'Neil BJ; Department of Emergency Medicine, Wayne State University, Detroit Receiving Hospital, Detroit, MI, USA., Sergot P; Department of Emergency Medicine, McGovern Medical School at UTHealth, Houston, TX, USA., Sanchez LD; Department of Emergency Medicine, Harvard Medical School, Boston, MA, USA.; Department of Emergency Medicine, Brigham and Women's Hospital, Boston, MA, USA., Bruce SE; Department of Psychological Sciences, University of Missouri - St. Louis, St. Louis, MO, USA., Harte SE; Department of Anesthesiology, University of Michigan Medical School, Ann Arbor, MI, USA.; Department of Internal Medicine-Rheumatology, University of Michigan Medical School, Ann Arbor, MI, USA., McLean SA; Department of Emergency Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Institute for Trauma Recovery, Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Ressler KJ; Department of Psychiatry, Harvard Medical School, Boston, MA, USA.; Division of Depression and Anxiety, McLean Hospital, Belmont, MA, USA., Koenen KC; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Harvard University, Boston, MA, USA., Denckla CA; Department of Social and Behavioral Sciences, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Source: Translational psychiatry [Transl Psychiatry] 2025 Oct 24; Vol. 15 (1), pp. 434. Date of Electronic Publication: 2025 Oct 24.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101562664 Publication Model: Electronic Cited Medium: Internet ISSN: 2158-3188 (Electronic) Linking ISSN: 21583188 NLM ISO Abbreviation: Transl Psychiatry Subsets: MEDLINE
Database: MEDLINE Ultimate
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