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RIPK3 promotes skin inflammation by enhancing IL-36α signaling and necroptosis in keratinocytes.

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Title: RIPK3 promotes skin inflammation by enhancing IL-36α signaling and necroptosis in keratinocytes.
Authors: Li QQ; The Institute of Clinical Pharmacology, Anhui Medical University, Key Laboratory of Anti-inflammatory and Immune Medicine, Ministry of Education, Anhui Collaborative Innovation Center of Anti-inflammatory and Immune Medicine, Hefei, China.; State Key Laboratory of Chemical Biology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China., Yang T; State Key Laboratory of Chemical Biology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.; School of Pharmacy, University of Chinese Academy of Sciences, Beijing, China., Ren JJ; The Institute of Clinical Pharmacology, Anhui Medical University, Key Laboratory of Anti-inflammatory and Immune Medicine, Ministry of Education, Anhui Collaborative Innovation Center of Anti-inflammatory and Immune Medicine, Hefei, China.; State Key Laboratory of Chemical Biology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China., Hui ZZ; School of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing, China., Lei SY; State Key Laboratory of Chemical Biology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.; School of Pharmacy, University of Chinese Academy of Sciences, Beijing, China., Feng CL; State Key Laboratory of Chemical Biology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China., Yang XQ; State Key Laboratory of Chemical Biology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China., Tang W; The Institute of Clinical Pharmacology, Anhui Medical University, Key Laboratory of Anti-inflammatory and Immune Medicine, Ministry of Education, Anhui Collaborative Innovation Center of Anti-inflammatory and Immune Medicine, Hefei, China. tangwei@simm.ac.cn.; State Key Laboratory of Chemical Biology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China. tangwei@simm.ac.cn.; School of Pharmacy, University of Chinese Academy of Sciences, Beijing, China. tangwei@simm.ac.cn.; School of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing, China. tangwei@simm.ac.cn.
Source: Cell death & disease [Cell Death Dis] 2025 Oct 24; Vol. 16 (1), pp. 759. Date of Electronic Publication: 2025 Oct 24.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: RIPK3 promotes skin inflammation by enhancing IL-36α signaling and necroptosis in keratinocytes.
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  Data: <searchLink fieldCode="AU" term="%22Li+QQ%22">Li QQ</searchLink>; The Institute of Clinical Pharmacology, Anhui Medical University, Key Laboratory of Anti-inflammatory and Immune Medicine, Ministry of Education, Anhui Collaborative Innovation Center of Anti-inflammatory and Immune Medicine, Hefei, China.; State Key Laboratory of Chemical Biology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Yang+T%22">Yang T</searchLink>; State Key Laboratory of Chemical Biology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.; School of Pharmacy, University of Chinese Academy of Sciences, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Ren+JJ%22">Ren JJ</searchLink>; The Institute of Clinical Pharmacology, Anhui Medical University, Key Laboratory of Anti-inflammatory and Immune Medicine, Ministry of Education, Anhui Collaborative Innovation Center of Anti-inflammatory and Immune Medicine, Hefei, China.; State Key Laboratory of Chemical Biology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Hui+ZZ%22">Hui ZZ</searchLink>; School of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing, China.<br /><searchLink fieldCode="AU" term="%22Lei+SY%22">Lei SY</searchLink>; State Key Laboratory of Chemical Biology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.; School of Pharmacy, University of Chinese Academy of Sciences, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Feng+CL%22">Feng CL</searchLink>; State Key Laboratory of Chemical Biology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Yang+XQ%22">Yang XQ</searchLink>; State Key Laboratory of Chemical Biology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China.<br /><searchLink fieldCode="AU" term="%22Tang+W%22">Tang W</searchLink>; The Institute of Clinical Pharmacology, Anhui Medical University, Key Laboratory of Anti-inflammatory and Immune Medicine, Ministry of Education, Anhui Collaborative Innovation Center of Anti-inflammatory and Immune Medicine, Hefei, China. tangwei@simm.ac.cn.; State Key Laboratory of Chemical Biology, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, China. tangwei@simm.ac.cn.; School of Pharmacy, University of Chinese Academy of Sciences, Beijing, China. tangwei@simm.ac.cn.; School of Chinese Materia Medica, Nanjing University of Chinese Medicine, Nanjing, China. tangwei@simm.ac.cn.
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  Data: <searchLink fieldCode="JN" term="%22101524092%22">Cell death & disease</searchLink> [Cell Death Dis] 2025 Oct 24; Vol. 16 (1), pp. 759. <i>Date of Electronic Publication: </i>2025 Oct 24.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Pub%2E+Group%22">Nature Pub. Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101524092 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2041-4889 (Electronic) <i>NLM ISO Abbreviation: </i>Cell Death Dis <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41136377
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        Value: 10.1038/s41419-025-08096-9
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              Text: 2025 Oct 24
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