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Monkeypox Virus Is Inhibited by Nucleoside Analogues Including the Acyclic Phosphonates Adefovir and Tenofovir In Vitro.

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Title: Monkeypox Virus Is Inhibited by Nucleoside Analogues Including the Acyclic Phosphonates Adefovir and Tenofovir In Vitro.
Authors: Lee J; Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine, Center for ViroScience and Cure, Atlanta, Georgia, USA.; Children's Healthcare of Atlanta, Atlanta, Georgia, USA., Zhang H; Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine, Center for ViroScience and Cure, Atlanta, Georgia, USA.; Children's Healthcare of Atlanta, Atlanta, Georgia, USA., Boggs EA; Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine, Center for ViroScience and Cure, Atlanta, Georgia, USA.; Children's Healthcare of Atlanta, Atlanta, Georgia, USA., Kilcullen J; Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine, Center for ViroScience and Cure, Atlanta, Georgia, USA.; Children's Healthcare of Atlanta, Atlanta, Georgia, USA., Moriarty M; Poxvirus and Rabies Branch, National Center for Emerging Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Division of High-Consequence Pathogens and Pathology, Atlanta, Georgia, USA., Du Y; Department of Pharmacology and Chemical Biology, Emory University School of Medicine, Atlanta, Georgia, USA.; Emory University School of Medicine, Emory Chemical Biology Discovery Center, Atlanta, Georgia, USA.; Winship Cancer Institute of Emory University, Atlanta, Georgia, USA., Fu H; Department of Pharmacology and Chemical Biology, Emory University School of Medicine, Atlanta, Georgia, USA.; Emory University School of Medicine, Emory Chemical Biology Discovery Center, Atlanta, Georgia, USA.; Winship Cancer Institute of Emory University, Atlanta, Georgia, USA.; Department of Hematology and Medical Oncology, Emory University, Atlanta, Georgia, USA., Lan S; Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine, Center for ViroScience and Cure, Atlanta, Georgia, USA.; Children's Healthcare of Atlanta, Atlanta, Georgia, USA., Hutson CL; Poxvirus and Rabies Branch, National Center for Emerging Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Division of High-Consequence Pathogens and Pathology, Atlanta, Georgia, USA., Satheshkumar PS; Poxvirus and Rabies Branch, National Center for Emerging Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Division of High-Consequence Pathogens and Pathology, Atlanta, Georgia, USA., Tedbury PR; Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine, Center for ViroScience and Cure, Atlanta, Georgia, USA.; Children's Healthcare of Atlanta, Atlanta, Georgia, USA., Sarafianos SG; Laboratory of Biochemical Pharmacology, Department of Pediatrics, Emory University School of Medicine, Center for ViroScience and Cure, Atlanta, Georgia, USA.; Children's Healthcare of Atlanta, Atlanta, Georgia, USA.
Source: Journal of medical virology [J Med Virol] 2025 Nov; Vol. 97 (11), pp. e70669.
Publication Type: Journal Article
Journal Info: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 7705876 Publication Model: Print Cited Medium: Internet ISSN: 1096-9071 (Electronic) Linking ISSN: 01466615 NLM ISO Abbreviation: J Med Virol Subsets: MEDLINE
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