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Broad H3K4me3 domains support oocyte genome silencing and maturation but are dispensable for repression in early embryos.

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Title: Broad H3K4me3 domains support oocyte genome silencing and maturation but are dispensable for repression in early embryos.
Authors: Skuland T; Department of Reproductive Medicine, Women's Clinic, Oslo University Hospital, 0855 Oslo, Norway.; Division of Gynaecology and Obstetrics, Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, 0450 Oslo, Norway.; CRESCO - Centre for Embryology and Healthy Development, Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, 0373 Oslo, Norway., Fosslie M; CRESCO - Centre for Embryology and Healthy Development, Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, 0373 Oslo, Norway.; Department of Microbiology, Division of Laboratory Medicine, Oslo University Hospital, 0373 Oslo, Norway., Khodeer S; Department of Microbiology, Division of Laboratory Medicine, Oslo University Hospital, 0373 Oslo, Norway., Alemu EA; Department of Microbiology, Division of Laboratory Medicine, Oslo University Hospital, 0373 Oslo, Norway., Johansen JV; Biotech Research & Innovation Centre (BRIC), University of Copenhagen, 2200 Copenhagen, Denmark., Indahl M; Department of Reproductive Medicine, Women's Clinic, Oslo University Hospital, 0855 Oslo, Norway.; CRESCO - Centre for Embryology and Healthy Development, Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, 0373 Oslo, Norway., Castroviejo BC; Department of Reproductive Medicine, Women's Clinic, Oslo University Hospital, 0855 Oslo, Norway.; CRESCO - Centre for Embryology and Healthy Development, Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, 0373 Oslo, Norway., Li Y; CRESCO - Centre for Embryology and Healthy Development, Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, 0373 Oslo, Norway.; Department of Microbiology, Division of Laboratory Medicine, Oslo University Hospital, 0373 Oslo, Norway., Lerdrup M; CRESCO - Centre for Embryology and Healthy Development, Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, 0373 Oslo, Norway.; DNRF Centre for Chromosome Stability, Department of Cellular and Molecular Medicine, University of Copenhagen, 2200 Copenhagen, Denmark., Dahl JA; CRESCO - Centre for Embryology and Healthy Development, Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, 0373 Oslo, Norway.; Department of Microbiology, Division of Laboratory Medicine, Oslo University Hospital, 0373 Oslo, Norway., Fedorcsak PZ; Department of Reproductive Medicine, Women's Clinic, Oslo University Hospital, 0855 Oslo, Norway.; Division of Gynaecology and Obstetrics, Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, 0450 Oslo, Norway.; CRESCO - Centre for Embryology and Healthy Development, Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, 0373 Oslo, Norway., Greggains GD; Department of Reproductive Medicine, Women's Clinic, Oslo University Hospital, 0855 Oslo, Norway.; CRESCO - Centre for Embryology and Healthy Development, Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, 0373 Oslo, Norway.
Source: Development (Cambridge, England) [Development] 2025 Nov 01; Vol. 152 (21). Date of Electronic Publication: 2025 Oct 27.
Publication Type: Journal Article
Journal Info: Publisher: Company Of Biologists Limited Country of Publication: England NLM ID: 8701744 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1477-9129 (Electronic) Linking ISSN: 09501991 NLM ISO Abbreviation: Development Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Broad H3K4me3 domains support oocyte genome silencing and maturation but are dispensable for repression in early embryos.
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  Data: <searchLink fieldCode="AU" term="%22Skuland+T%22">Skuland T</searchLink>; Department of Reproductive Medicine, Women's Clinic, Oslo University Hospital, 0855 Oslo, Norway.; Division of Gynaecology and Obstetrics, Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, 0450 Oslo, Norway.; CRESCO - Centre for Embryology and Healthy Development, Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, 0373 Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Fosslie+M%22">Fosslie M</searchLink>; CRESCO - Centre for Embryology and Healthy Development, Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, 0373 Oslo, Norway.; Department of Microbiology, Division of Laboratory Medicine, Oslo University Hospital, 0373 Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Khodeer+S%22">Khodeer S</searchLink>; Department of Microbiology, Division of Laboratory Medicine, Oslo University Hospital, 0373 Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Alemu+EA%22">Alemu EA</searchLink>; Department of Microbiology, Division of Laboratory Medicine, Oslo University Hospital, 0373 Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Johansen+JV%22">Johansen JV</searchLink>; Biotech Research & Innovation Centre (BRIC), University of Copenhagen, 2200 Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Indahl+M%22">Indahl M</searchLink>; Department of Reproductive Medicine, Women's Clinic, Oslo University Hospital, 0855 Oslo, Norway.; CRESCO - Centre for Embryology and Healthy Development, Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, 0373 Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Castroviejo+BC%22">Castroviejo BC</searchLink>; Department of Reproductive Medicine, Women's Clinic, Oslo University Hospital, 0855 Oslo, Norway.; CRESCO - Centre for Embryology and Healthy Development, Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, 0373 Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Li+Y%22">Li Y</searchLink>; CRESCO - Centre for Embryology and Healthy Development, Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, 0373 Oslo, Norway.; Department of Microbiology, Division of Laboratory Medicine, Oslo University Hospital, 0373 Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Lerdrup+M%22">Lerdrup M</searchLink>; CRESCO - Centre for Embryology and Healthy Development, Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, 0373 Oslo, Norway.; DNRF Centre for Chromosome Stability, Department of Cellular and Molecular Medicine, University of Copenhagen, 2200 Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Dahl+JA%22">Dahl JA</searchLink>; CRESCO - Centre for Embryology and Healthy Development, Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, 0373 Oslo, Norway.; Department of Microbiology, Division of Laboratory Medicine, Oslo University Hospital, 0373 Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Fedorcsak+PZ%22">Fedorcsak PZ</searchLink>; Department of Reproductive Medicine, Women's Clinic, Oslo University Hospital, 0855 Oslo, Norway.; Division of Gynaecology and Obstetrics, Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, 0450 Oslo, Norway.; CRESCO - Centre for Embryology and Healthy Development, Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, 0373 Oslo, Norway.<br /><searchLink fieldCode="AU" term="%22Greggains+GD%22">Greggains GD</searchLink>; Department of Reproductive Medicine, Women's Clinic, Oslo University Hospital, 0855 Oslo, Norway.; CRESCO - Centre for Embryology and Healthy Development, Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, 0373 Oslo, Norway.
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              Text: 2025 Nov 01
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