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Early phase development of PI3kinase inhibitors for anticancer therapies.

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Title: Early phase development of PI3kinase inhibitors for anticancer therapies.
Authors: Caputo C; Laboratory of Molecular and Precision Oncology, Institute of Genetic Research, Biogem Scarl, Ariano Irpino, Italy.; Department of Precision Medicine, University of Campania 'Luigi Vanvitelli', Naples, Italy., Lombardi A; Department of Precision Medicine, University of Campania 'Luigi Vanvitelli', Naples, Italy.; Department of Theoretical and Applied Sciences, eCampus University, Novedrate, Italy., Vicario M; Laboratory of Molecular and Precision Oncology, Institute of Genetic Research, Biogem Scarl, Ariano Irpino, Italy., Cautela D; Department of Theoretical and Applied Sciences, eCampus University, Novedrate, Italy., Addeo R; Division of Oncology, Hospital of Frattamaggiore 'S. Giovanni di Dio', Frattaminore (NA), Italy., Melisi F; Laboratory of Molecular and Precision Oncology, Institute of Genetic Research, Biogem Scarl, Ariano Irpino, Italy., Grimaldi A; U.P. Cytometric and Mutational Diagnostics, Vanvitelli Hospital, University of Campania 'Luigi Vanvitelli', Naples, Italy., Necas A; CEITEC - Central European Institute of Technology, University of Veterinary and Pharmaceutical Sciences Brno, Brno, Czechia., Amler E; Department of Biophysics, 2nd Faculty of Medicine, Charles University in Prague, Prague, Czech Republic., Sperlongano R; Department of Precision Medicine, University of Campania 'Luigi Vanvitelli', Naples, Italy., Caraglia M; Laboratory of Molecular and Precision Oncology, Institute of Genetic Research, Biogem Scarl, Ariano Irpino, Italy.; Department of Precision Medicine, University of Campania 'Luigi Vanvitelli', Naples, Italy.
Source: Expert opinion on investigational drugs [Expert Opin Investig Drugs] 2025 Nov; Vol. 34 (11), pp. 905-920. Date of Electronic Publication: 2025 Nov 06.
Publication Type: Journal Article; Review
Journal Info: Publisher: Taylor & Francis Country of Publication: England NLM ID: 9434197 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-7658 (Electronic) Linking ISSN: 13543784 NLM ISO Abbreviation: Expert Opin Investig Drugs Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Early phase development of PI3kinase inhibitors for anticancer therapies.
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  Data: <searchLink fieldCode="AU" term="%22Caputo+C%22">Caputo C</searchLink>; Laboratory of Molecular and Precision Oncology, Institute of Genetic Research, Biogem Scarl, Ariano Irpino, Italy.; Department of Precision Medicine, University of Campania 'Luigi Vanvitelli', Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Lombardi+A%22">Lombardi A</searchLink>; Department of Precision Medicine, University of Campania 'Luigi Vanvitelli', Naples, Italy.; Department of Theoretical and Applied Sciences, eCampus University, Novedrate, Italy.<br /><searchLink fieldCode="AU" term="%22Vicario+M%22">Vicario M</searchLink>; Laboratory of Molecular and Precision Oncology, Institute of Genetic Research, Biogem Scarl, Ariano Irpino, Italy.<br /><searchLink fieldCode="AU" term="%22Cautela+D%22">Cautela D</searchLink>; Department of Theoretical and Applied Sciences, eCampus University, Novedrate, Italy.<br /><searchLink fieldCode="AU" term="%22Addeo+R%22">Addeo R</searchLink>; Division of Oncology, Hospital of Frattamaggiore 'S. Giovanni di Dio', Frattaminore (NA), Italy.<br /><searchLink fieldCode="AU" term="%22Melisi+F%22">Melisi F</searchLink>; Laboratory of Molecular and Precision Oncology, Institute of Genetic Research, Biogem Scarl, Ariano Irpino, Italy.<br /><searchLink fieldCode="AU" term="%22Grimaldi+A%22">Grimaldi A</searchLink>; U.P. Cytometric and Mutational Diagnostics, Vanvitelli Hospital, University of Campania 'Luigi Vanvitelli', Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Necas+A%22">Necas A</searchLink>; CEITEC - Central European Institute of Technology, University of Veterinary and Pharmaceutical Sciences Brno, Brno, Czechia.<br /><searchLink fieldCode="AU" term="%22Amler+E%22">Amler E</searchLink>; Department of Biophysics, 2nd Faculty of Medicine, Charles University in Prague, Prague, Czech Republic.<br /><searchLink fieldCode="AU" term="%22Sperlongano+R%22">Sperlongano R</searchLink>; Department of Precision Medicine, University of Campania 'Luigi Vanvitelli', Naples, Italy.<br /><searchLink fieldCode="AU" term="%22Caraglia+M%22">Caraglia M</searchLink>; Laboratory of Molecular and Precision Oncology, Institute of Genetic Research, Biogem Scarl, Ariano Irpino, Italy.; Department of Precision Medicine, University of Campania 'Luigi Vanvitelli', Naples, Italy.
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  Data: <searchLink fieldCode="JN" term="%229434197%22">Expert opinion on investigational drugs</searchLink> [Expert Opin Investig Drugs] 2025 Nov; Vol. 34 (11), pp. 905-920. <i>Date of Electronic Publication: </i>2025 Nov 06.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Taylor+%26+Francis%22">Taylor & Francis </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>9434197 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1744-7658 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2213543784%22">13543784 </searchLink><i>NLM ISO Abbreviation: </i>Expert Opin Investig Drugs <i>Subsets: </i>MEDLINE
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              Text: 2025 Nov
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