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SARS-CoV-2 Infection of Lung Epithelia Leads to an Increase in the Cleavage and Translocation of RNase-III Drosha; Loss of Drosha Is Associated with a Decrease in Viral Replication.

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Title: SARS-CoV-2 Infection of Lung Epithelia Leads to an Increase in the Cleavage and Translocation of RNase-III Drosha; Loss of Drosha Is Associated with a Decrease in Viral Replication.
Authors: Winters MT; Department of Microbiology, Immunology and Cell Biology, West Virginia University School of Medicine, West Virginia University, Morgantown, WV 26506, USA., Westemeier-Rice ES; West Virginia University Cancer Institute, West Virginia University, Morgantown, WV 26506, USA., Rawson TW; Department of Microbiology, Immunology and Cell Biology, West Virginia University School of Medicine, West Virginia University, Morgantown, WV 26506, USA., Patel KJ; West Virginia University School of Medicine, West Virginia University, Morgantown, WV 26506, USA., Sankey GM; Department of Microbiology, Immunology and Cell Biology, West Virginia University School of Medicine, West Virginia University, Morgantown, WV 26506, USA., Dixon-Gross M; Department of Biology, West Virginia University, Morgantown, WV 26506, USA., McHugh OR; Department of Microbiology, Immunology and Cell Biology, West Virginia University School of Medicine, West Virginia University, Morgantown, WV 26506, USA., Hashemipour N; West Virginia University Cancer Institute, West Virginia University, Morgantown, WV 26506, USA., Carroll ML; West Virginia University Cancer Institute, West Virginia University, Morgantown, WV 26506, USA., Wilkerson IR; Department of Microbiology, Immunology and Cell Biology, West Virginia University School of Medicine, West Virginia University, Morgantown, WV 26506, USA., Martinez I; Department of Microbiology, Immunology and Cell Biology, West Virginia University School of Medicine, West Virginia University, Morgantown, WV 26506, USA.; West Virginia University Cancer Institute, West Virginia University, Morgantown, WV 26506, USA.
Source: Genes [Genes (Basel)] 2025 Oct 20; Vol. 16 (10). Date of Electronic Publication: 2025 Oct 20.
Publication Type: Journal Article
Journal Info: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101551097 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4425 (Electronic) Linking ISSN: 20734425 NLM ISO Abbreviation: Genes (Basel) Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: SARS-CoV-2 Infection of Lung Epithelia Leads to an Increase in the Cleavage and Translocation of RNase-III Drosha; Loss of Drosha Is Associated with a Decrease in Viral Replication.
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  Data: <searchLink fieldCode="AU" term="%22Winters+MT%22">Winters MT</searchLink>; Department of Microbiology, Immunology and Cell Biology, West Virginia University School of Medicine, West Virginia University, Morgantown, WV 26506, USA.<br /><searchLink fieldCode="AU" term="%22Westemeier-Rice+ES%22">Westemeier-Rice ES</searchLink>; West Virginia University Cancer Institute, West Virginia University, Morgantown, WV 26506, USA.<br /><searchLink fieldCode="AU" term="%22Rawson+TW%22">Rawson TW</searchLink>; Department of Microbiology, Immunology and Cell Biology, West Virginia University School of Medicine, West Virginia University, Morgantown, WV 26506, USA.<br /><searchLink fieldCode="AU" term="%22Patel+KJ%22">Patel KJ</searchLink>; West Virginia University School of Medicine, West Virginia University, Morgantown, WV 26506, USA.<br /><searchLink fieldCode="AU" term="%22Sankey+GM%22">Sankey GM</searchLink>; Department of Microbiology, Immunology and Cell Biology, West Virginia University School of Medicine, West Virginia University, Morgantown, WV 26506, USA.<br /><searchLink fieldCode="AU" term="%22Dixon-Gross+M%22">Dixon-Gross M</searchLink>; Department of Biology, West Virginia University, Morgantown, WV 26506, USA.<br /><searchLink fieldCode="AU" term="%22McHugh+OR%22">McHugh OR</searchLink>; Department of Microbiology, Immunology and Cell Biology, West Virginia University School of Medicine, West Virginia University, Morgantown, WV 26506, USA.<br /><searchLink fieldCode="AU" term="%22Hashemipour+N%22">Hashemipour N</searchLink>; West Virginia University Cancer Institute, West Virginia University, Morgantown, WV 26506, USA.<br /><searchLink fieldCode="AU" term="%22Carroll+ML%22">Carroll ML</searchLink>; West Virginia University Cancer Institute, West Virginia University, Morgantown, WV 26506, USA.<br /><searchLink fieldCode="AU" term="%22Wilkerson+IR%22">Wilkerson IR</searchLink>; Department of Microbiology, Immunology and Cell Biology, West Virginia University School of Medicine, West Virginia University, Morgantown, WV 26506, USA.<br /><searchLink fieldCode="AU" term="%22Martinez+I%22">Martinez I</searchLink>; Department of Microbiology, Immunology and Cell Biology, West Virginia University School of Medicine, West Virginia University, Morgantown, WV 26506, USA.; West Virginia University Cancer Institute, West Virginia University, Morgantown, WV 26506, USA.
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  Data: <searchLink fieldCode="JN" term="%22101551097%22">Genes</searchLink> [Genes (Basel)] 2025 Oct 20; Vol. 16 (10). <i>Date of Electronic Publication: </i>2025 Oct 20.
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